Maribavir Dosage

Medically reviewed by Drugs.com. Last updated on Mar 30, 2022.

Usual Adult Dose for CMV Infection

400 mg orally twice a day

Use: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet

Usual Pediatric Dose for CMV Infection

12 years or older:

• At least 35 kg: 400 mg orally twice a day

Use: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet

Renal Dose Adjustments

Mild, moderate, or severe renal dysfunction: No adjustment recommended.
ESRD: Data not available

Liver Dose Adjustments

Mild (Child-Pugh A) or moderate (Child-Pugh B) liver dysfunction: No adjustment recommended.
Severe liver dysfunction: Data not available

Dose Adjustments

Coadministration with carbamazepine: Maribavir 800 mg orally twice a day
Coadministration with phenytoin or phenobarbital: Maribavir 1200 mg orally twice a day

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

ESRD on dialysis: Data not available

Comments:

• This drug is highly bound to plasma proteins; significant removal via dialysis is unlikely.

Other Comments

Administration advice:

• Administer with or without food.

Storage requirements:

• Store at 20C to 25C (68F to 77F); brief exposure to 15C to 30C (59F to 86F) permitted.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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