Maribavir Dosage
Medically reviewed by Drugs.com. Last updated on Mar 30, 2022.
Applies to the following strengths: 200 mg
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for CMV Infection
400 mg orally twice a day
Use: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet
Usual Pediatric Dose for CMV Infection
12 years or older:
- At least 35 kg: 400 mg orally twice a day
Use: For the treatment of patients with posttransplant CMV infection/disease refractory to treatment (with or without genotypic resistance) with ganciclovir, valganciclovir, cidofovir, or foscarnet
Renal Dose Adjustments
Mild, moderate, or severe renal dysfunction: No adjustment recommended.
ESRD: Data not available
Liver Dose Adjustments
Mild (Child-Pugh A) or moderate (Child-Pugh B) liver dysfunction: No adjustment recommended.
Severe liver dysfunction: Data not available
Dose Adjustments
Coadministration with carbamazepine: Maribavir 800 mg orally twice a day
Coadministration with phenytoin or phenobarbital: Maribavir 1200 mg orally twice a day
Precautions
CONTRAINDICATIONS: None
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
ESRD on dialysis: Data not available
Comments:
- This drug is highly bound to plasma proteins; significant removal via dialysis is unlikely.
Other Comments
Administration advice:
- Administer with or without food.
Storage requirements:
- Store at 20C to 25C (68F to 77F); brief exposure to 15C to 30C (59F to 86F) permitted.
Patient advice:
- Read the US FDA-approved patient labeling (Patient Information).
More about maribavir
- Check interactions
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- During pregnancy
- Drug class: miscellaneous antivirals
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