Jynneos Dosage
Generic name: VACCINIA VIRUS MODIFIED STRAIN ANKARA-BAVARIAN NORDIC NON-REPLICATING ANTIGEN 500000001 in 0.5mL
Dosage form: injection, suspension
Drug class: Viral vaccines
Medically reviewed by Drugs.com. Last updated on Mar 31, 2025.
For subcutaneous use.
2.1 JYNNEOS Presentations
JYNNEOS is supplied in two presentations, a one vial-presentation and a two-vial presentation.
One-Vial Presentation
The one-vial presentation contains JYNNEOS in a single vial with a yellow cap and does not require reconstitution before use.
Two-Vial Presentation
The two-vial presentation includes a vial with a yellow cap containing Lyophilized Antigen Component (Vial A) and a vial with a blue cap containing Diluent Component (Vial B). The Lyophilized Antigen Component must be reconstituted with the Diluent Component to form JYNNEOS prior to administration.
Preparation
Instructions for JYNNEOS One-Vial Presentation
Allow the vaccine to thaw and reach room temperature before use. Once thawed, the vaccine may be kept at +2°C to +8°C (+36°F to +46°F) for 4 weeks. Protect from light during storage.
Do not refreeze.
Swirl the vial gently before use for at least 30 seconds. Withdraw a dose of 0.5 mL into a sterile syringe for injection.
Reconstitution Instructions for JYNNEOS Two-Vial Presentation
Reconstitute the Lyophilized Antigen Component (Vial A, yellow cap) with Diluent Component (Vial B, blue cap) to form JYNNEOS, as described in Figure 1 through Figure 4.
After reconstitution, the vaccine may be stored at +2°C to +8°C (+36°F to +46°F) for 12 hours. Protect from light during storage.
2.3 Administration
JYNNEOS is a milky, light yellow to pale white colored suspension. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. If either of these conditions exist, the vaccine should not be administered.
Administer each 0.5 mL dose of JYNNEOS subcutaneously.
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