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Trace elements with selenium and iodide Disease Interactions

There are 6 disease interactions with trace elements with selenium and iodide.

Moderate

Chromium/selenium/zinc (applies to trace elements with selenium and iodide) renal dysfunction

Moderate Potential Hazard, Moderate plausibility.

The trace metals, chromium and zinc, are excreted primarily in the urine. Selenium is partially excreted in the urine. Supplemental doses of these agents may need to be adjusted, reduced, or omitted in patients with renal dysfunction.

References

  1. "Product Information. Galzin (zinc acetate)." Teva Pharmaceuticals USA PROD (2001):
  2. "Product Information. Chroma-Pak (chromic chloride hexahydrate)." Apothecon Inc (2022):
  3. "Product Information. Sele-Pak (selenium)." Fujisawa PROD
Moderate

Copper/manganese (applies to trace elements with selenium and iodide) elimination

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Biliary Obstruction, Liver Disease, Biliary Obstruction, Liver Disease

The trace elements, copper and manganese, are excreted in the bile. Copper and manganese doses may need to be adjusted, reduced, or omitted in patients with liver disease or biliary obstruction.

References

  1. "Product Information. Copper Sulfate (copper sulfate)." Humco Holding Group PROD (2001):
  2. "Product Information. Manganese Chloride (manganese chloride)." Abbott Pharmaceutical PROD (2001):
  3. "Product Information. Manganese Sulfate (manganese sulfate)." American Regent Laboratories Inc PROD (2001):
Moderate

Iodine (applies to trace elements with selenium and iodide) thyroid/metabolic abnormality

Moderate Potential Hazard, High plausibility. Applicable conditions: Hypothyroidism, Hyperthyroidism

Elevated serum iodine levels can lead to altered thyroid function and metabolic abnormalities in patients receiving oral iodine therapy as well as topical therapy. Iodine should be used cautiously in patients with thyroid disorders. Monitoring thyroid function is recommended.

References

  1. "Product Information. Betadine (povidone iodine topical)." Akorn Inc PROD
  2. "Product Information. Betadine (povidone iodine topical)." Purdue Frederick Company PROD
  3. "Product Information. Iodopen (sodium iodide)." Fujisawa PROD (2001):
Moderate

Manganese preparations (applies to trace elements with selenium and iodide) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Manganese sulfate and manganese chloride preparations contain aluminum and may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which also contain aluminum. Patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration. Caution is advised in patients with renal impairment, particularly in premature or neonates patients.

References

  1. "Product Information. Manganese Chloride (manganese chloride)." Abbott Pharmaceutical PROD (2001):
  2. "Product Information. Manganese Sulfate (manganese sulfate)." American Regent Laboratories Inc PROD (2001):
Moderate

Sodium iodide (applies to trace elements with selenium and iodide) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Sodium iodide is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.

References

  1. "Product Information. Iodopen (sodium iodide)." Fujisawa PROD (2001):
Moderate

Trace metals (applies to trace elements with selenium and iodide) malabsorption syndromes

Moderate Potential Hazard, Moderate plausibility.

The trace metals manganese, chromium, copper, selenium, and zinc are absorbed in the GI tract from dietary sources and following administration of oral supplements. GI absorption may be decreased in patients with malabsorption syndromes. Therefore, larger dosages may be required when these supplements are given orally. Parenteral administration may be appropriate.

References

  1. "Product Information. Galzin (zinc acetate)." Teva Pharmaceuticals USA PROD (2001):
  2. "Product Information. Chroma-Pak (chromic chloride hexahydrate)." Apothecon Inc (2022):
  3. "Product Information. Sele-Pak (selenium)." Fujisawa PROD
  4. "Product Information. Copper Sulfate (copper sulfate)." Humco Holding Group PROD (2001):
  5. "Product Information. Manganese Chloride (manganese chloride)." Abbott Pharmaceutical PROD (2001):
  6. "Product Information. Manganese Sulfate (manganese sulfate)." American Regent Laboratories Inc PROD (2001):
View all 6 references

Trace elements with selenium and iodide drug interactions

There are 141 drug interactions with trace elements with selenium and iodide.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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