Equaline Heartburn Relief Disease Interactions
There are 6 disease interactions with Equaline Heartburn Relief (ranitidine).
H2 antagonists (applies to Equaline Heartburn Relief) GI bleeding
Major Potential Hazard, Moderate plausibility. Applicable conditions: Gastrointestinal Hemorrhage
Histamine H2 receptor antagonists should not be used in the presence of vomit with blood, or bloody or black stools. These might be serious conditions and the diagnosis needs to be ruled out.
Ranitidine (applies to Equaline Heartburn Relief) porphyria
Major Potential Hazard, Moderate plausibility.
Ranitidine may rarely precipitate acute porphyria attacks and should be avoided in patients with a history of acute porphyria.
Ranitidine (applies to Equaline Heartburn Relief) hemodialysis
Moderate Potential Hazard, High plausibility.
Ranitidine is partially removed by hemodialysis and should be administered after dialysis.
Ranitidine (applies to Equaline Heartburn Relief) liver disease
Moderate Potential Hazard, Low plausibility.
Ranitidine is partially metabolized by the liver. Although dosage reductions are generally not necessary, therapy with ranitidine should be administered cautiously in patients with liver disease. Elevated ALT (SGPT) has been observed in patients receiving ranitidine intravenously at dosages greater than those normally recommended for 5 days or more.
Ranitidine (applies to Equaline Heartburn Relief) PKU
Moderate Potential Hazard, High plausibility. Applicable conditions: Phenylketonuria
Zantac (brand of ranitidine) 150 EFFERdose tablets and granules both contain 16.84 mg of phenylalanine per each 150 mg of ranitidine. The phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).
Ranitidine (applies to Equaline Heartburn Relief) renal dysfunction
Moderate Potential Hazard, High plausibility.
Ranitidine is primarily eliminated by the kidney. Although the drug is generally well-tolerated, the daily dosage should initially be reduced in patients with moderate to severe renal impairment (CrCl < 50 mL/min). If necessary, the daily dosage may be increased with caution.
Equaline Heartburn Relief drug interactions
There are 141 drug interactions with Equaline Heartburn Relief (ranitidine).
Equaline Heartburn Relief alcohol/food interactions
There is 1 alcohol/food interaction with Equaline Heartburn Relief (ranitidine).
More about Equaline Heartburn Relief (ranitidine)
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- During pregnancy
- Drug class: H2 antagonists
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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