Pegunigalsidase alfa Disease Interactions
There is 1 disease interaction with pegunigalsidase alfa.
Alpha-galactosidase A proteins (applies to pegunigalsidase alfa) cardiac function
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease
Appropriate medical support measures should be readily available when administering alpha-galactosidase A enzyme replacement therapy (ERT) due to the potential for severe infusion-associated reactions. Compromised cardiac function may predispose patients to a higher risk of severe complications from infusion-associated reactions. Closely monitor patients with compromised cardiac function during administration of ERT.
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Pegunigalsidase alfa drug interactions
There are 6 drug interactions with pegunigalsidase alfa.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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