Papaverine Disease Interactions
There are 2 disease interactions with papaverine.
Papaverine derivatives (applies to papaverine) complete AV heart block
Major Potential Hazard, High plausibility.
The use of papaverine and papaverine derivatives is contraindicated in patients with complete AV heart block. When conduction is depressed, these agents can induce transient ectopic rhythms of ventricular origin, either premature beats or paroxysmal tachycardia. Therapy with these agents should be administered cautiously in patients with conduction disturbances, including sinus bradyarrhythmia and partial or first-degree AV block.
Papaverine derivatives (applies to papaverine) glaucoma
Moderate Potential Hazard, High plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension
The use of papaverine derivatives has been associated with an increase in intraocular pressure. Therapy with papaverine derivatives should be administered cautiously in patients with glaucoma.
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Papaverine drug interactions
There are 354 drug interactions with papaverine.
Papaverine alcohol/food interactions
There is 1 alcohol/food interaction with papaverine.
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- Drug class: peripheral vasodilators
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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