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Papaverine Side Effects

Applies to papaverine: oral capsule extended release, oral tablet

Other dosage forms:

Along with its needed effects, papaverine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking papaverine:


  • Abdominal pain or tenderness
  • blurred or double vision
  • change in ability to see colors, especially blue or yellow
  • clay-colored stools
  • dark urine
  • decreased appetite
  • deep, slow breathing
  • drowsiness
  • fatigue
  • fever
  • headache
  • insomnia
  • itching
  • loss of appetite
  • nausea and vomiting
  • painful or prolonged erection of the penis
  • skin rash
  • swelling of the feet or lower legs
  • trouble with breathing
  • unusual tiredness or weakness
  • vomiting
  • weakness
  • yellow eyes or skin

Some side effects of papaverine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

  • Constipation
  • diarrhea
  • dizziness or lightheadedness
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • feeling of constant movement of self or surroundings
  • flushed face
  • itching skin
  • nervousness
  • palpitations
  • pounding in the ears
  • sensation of spinning
  • sleepiness or unusual drowsiness
  • slow or fast heartbeat

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.