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Pavagen Disease Interactions

There are 2 disease interactions with Pavagen (papaverine).

Major

Papaverine derivatives (applies to Pavagen) complete AV heart block

Major Potential Hazard, High plausibility.

The use of papaverine and papaverine derivatives is contraindicated in patients with complete AV heart block. When conduction is depressed, these agents can induce transient ectopic rhythms of ventricular origin, either premature beats or paroxysmal tachycardia. Therapy with these agents should be administered cautiously in patients with conduction disturbances, including sinus bradyarrhythmia and partial or first-degree AV block.

References

  1. (2001) "Product Information. Papacon (papaverine)." Hoechst Marion Roussel
Moderate

Papaverine derivatives (applies to Pavagen) glaucoma

Moderate Potential Hazard, High plausibility. Applicable conditions: Glaucoma/Intraocular Hypertension

The use of papaverine derivatives has been associated with an increase in intraocular pressure. Therapy with papaverine derivatives should be administered cautiously in patients with glaucoma.

References

  1. (2001) "Product Information. Papacon (papaverine)." Hoechst Marion Roussel

Pavagen drug interactions

There are 349 drug interactions with Pavagen (papaverine).

Pavagen alcohol/food interactions

There is 1 alcohol/food interaction with Pavagen (papaverine).

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More about Pavagen (papaverine)

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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