Minoxidil/niacinamide topical Disease Interactions
There is 1 disease interaction with minoxidil / niacinamide topical.
Minoxidil topical (applies to minoxidil/niacinamide topical) systemic effects
Moderate Potential Hazard, Low plausibility. Applicable conditions: Congestive Heart Failure, Fluid Retention, Sunburn, Arrhythmias, Ischemic Heart Disease
In general, topically applied minoxidil is poorly absorbed from the normal, intact scalp. However, alteration in scalp epidermal integrity (e.g., abrasion, sunburn, psoriasis) can increase percutaneous absorption with resultant systemic effects, including sodium and water retention, local or generalized edema, pericardial effusion, pericarditis, tamponade, tachycardia, and worsening or development of angina. Therapy with minoxidil should be avoided in patients with diminished or altered scalp integrity that may lead to enhanced systemic absorption, particularly in the presence of underlying cardiovascular dysfunction or fluid retention.
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Minoxidil/niacinamide topical drug interactions
There are 39 drug interactions with minoxidil / niacinamide topical.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
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