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Hiberix Disease Interactions

There are 2 disease interactions with Hiberix (haemophilus b conjugate (prp-t) vaccine).

Moderate

Vaccines (applies to Hiberix) IM injection

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Thrombocytopathy, Coagulation Defect

In patients with thrombocytopenia or coagulation disorders, IM injections may produce bleeding and hematomas. Patients with a platelet count less than 50,000/mm3 are at an increased risk. Caution is advised if the vaccine (e.g., plague vaccine; hepatitis A and B vaccines; aluminum-adsorbed DTaP, DTP, DT, or Td) must be administered IM. The risk of bleeding may be minimized by vaccination immediately after the administration of replacement factor, use of a 23-gauge (or smaller) needle, and immediate application of direct pressure to the vaccination site for at least 2 minutes.

References (10)
  1. (2001) "Product Information. Plague Vaccine (plague vaccine)." Greer Laboratories Inc
  2. "Product Information. Cholera Vaccine (cholera vaccine)." Wyeth-Ayerst Laboratories
  3. "Product Information. Havrix (HepA) (hepatitis A adult vaccine)." SmithKline Beecham
  4. (2022) "Product Information. Engerix-B (HepB) (hepatitis B adult vaccine)." Apothecon Inc
  5. (2005) "Product Information. Menactra (meningococcal conjugate vaccine)." sanofi pasteur
  6. (2022) "Product Information. ActHIB (Hib) (haemophilus b conjugate (PRP-T) vaccine)." sanofi pasteur
  7. (2010) "Product Information. Imogam Rabies-HT (rabies immune globulin, human)." sanofi pasteur
  8. (2015) "Product Information. Hyperrab S/D (rabies immune globulin, human)." Grifols Therapeutics
  9. (2022) "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc
  10. (2024) "Product Information. Mresvia Prefilled Syringe (cvx 326) (RSV mRNA vaccine (cvx 326))." Moderna US, Inc
Moderate

Vaccines (live attenuated/toxoid) (applies to Hiberix) immunocompromised

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Immunodeficiency

The expected antibody responses may not be obtained when live attenuated vaccines and/or toxoids are administered to immunosuppressed persons, including those receiving immunosuppressive therapy. Caution and close monitoring is advised.

References (8)
  1. (2005) "Product Information. Menactra (meningococcal conjugate vaccine)." sanofi pasteur
  2. (2022) "Product Information. ActHIB (Hib) (haemophilus b conjugate (PRP-T) vaccine)." sanofi pasteur
  3. (2022) "Product Information. Bexsero (meningococcal group B vaccine)." Novartis Vaccines & Diagnostics Inc
  4. (2022) "Product Information. Trumenba (meningococcal group B vaccine)." Pfizer U.S. Pharmaceuticals Group
  5. (2022) "Product Information. Hiberix (Hib) (haemophilus b conjugate (PRP-T) vaccine)." GlaxoSmithKline
  6. (2016) "Product Information. Vaxchora (cholera vaccine, live)." PaxVax
  7. (2022) "Product Information. Vaxchora (cholera vaccine, live)." Emergent Travel Health, Inc
  8. (2023) "Product Information. Ixchiq (cvx 317) (chikungunya vaccine, live (cvx 317))." Valneva USA

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Hiberix drug interactions

There are 298 drug interactions with Hiberix (haemophilus b conjugate (prp-t) vaccine).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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