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Enasidenib Disease Interactions

There is 1 disease interaction with enasidenib.

Moderate

Enasidenib (applies to enasidenib) hyperbilirubinemia

Moderate Potential Hazard, Moderate plausibility.

The use of enasidenib may interfere with bilirubin metabolism through inhibition of UGT1A1. It is recommended to advise patients to report any changes to the color of their skin or the whites of their eyes to their healthcare provider for further evaluation. Evaluate for signs and symptoms of jaundice to rule out any conditions that may cause hyperbilirubinemia.

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Enasidenib drug interactions

There are 82 drug interactions with enasidenib.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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