Benzocaine/phenol/povidone iodine topical Disease Interactions
There are 2 disease interactions with benzocaine / phenol / povidone iodine topical.
Benzocaine (applies to benzocaine/phenol/povidone iodine topical) methemoglobinemia
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: G-6-PD Deficiency
Rarely, benzocaine has induced methemoglobinemia resulting in respiratory distress and cyanosis. Therapy with benzocaine should be administered cautiously to patients with or predisposed to methemoglobinemia. If life-threatening or severe methemoglobinemia develops, methylene blue infused at a dosage of 1 to 2 mg/kg body weight will rapidly reverse or improve the condition except in G-6-PD-deficient patients.
Iodine (applies to benzocaine/phenol/povidone iodine topical) thyroid/metabolic abnormality
Moderate Potential Hazard, Low plausibility. Applicable conditions: Hypothyroidism, Hyperthyroidism
Elevated serum iodine levels can lead to altered thyroid function and metabolic abnormalities in patients receiving oral iodine therapy as well as topical therapy. Iodine should be used cautiously in patients with thyroid disorders. Monitoring thyroid function is recommended.
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Benzocaine/phenol/povidone iodine topical drug interactions
There are 55 drug interactions with benzocaine / phenol / povidone iodine topical.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.