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Cis Sulfur Colloid

Generic Name: technetium tc 99m sulfurcolloid (Oral route, Route Not Applicable)

tek-NEE-see-um Tc 99m SUL-fyoor-coh-loid

Commonly used brand name(s)

In the U.S.

  • Cis Sulfur Colloid
  • Technetium TC 99m TSC

Available Dosage Forms:

  • Kit

Uses For Cis Sulfur Colloid

Technetium Tc 99m sulfur colloid is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs.

Technetium Tc 99m sulfur colloid is used to help your doctor see an image of your esophagus, stomach, and lungs to see how well they are working. This medicine is used to help diagnose gastroesophageal reflux disease and pulmonary aspiration.

This medicine is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.

Before Using Cis Sulfur Colloid

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of technetium Tc 99m sulfur colloid in children.


Although appropriate studies on the relationship of age to the effects of technetium Tc 99m sulfur colloid have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.


Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:

  • Cancer—Use with caution. May make this condition worse.

Proper Use of technetium tc 99m sulfurcolloid

This section provides information on the proper use of a number of products that contain technetium tc 99m sulfurcolloid. It may not be specific to Cis Sulfur Colloid. Please read with care.

A doctor or other trained health professional will give you or your child this medicine in a hospital or clinic. This medicine is given by mouth or by a nasogastric tube.

If this medicine is given to children by mouth, it should be combined with a milk feeding. If this medicine is given to children by a nasogastric tube, it is administered into the stomach and then followed with a dextrose or milk feeding.

Precautions While Using Cis Sulfur Colloid

It is very important that your doctor check you or your child closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes. If these side effects occur, get emergency help at once.

You may be exposed to radiation when you are given this medicine. This may also increase your risk to have cancer (especially in children). Talk with your doctor if you or your child have concerns about this.

If you are a woman who can get pregnant, the imaging procedures should be done within 10 days after the start of your monthly period or a pregnancy test should be performed within 48 hours before the procedure.

Cis Sulfur Colloid Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common
  • Cold, clammy skin
  • confusion
  • cough
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • fast, weak pulse
  • hives or welts
  • itching
  • lightheadedness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rash
  • redness of the skin
  • shortness of breath
  • sweating
  • tightness in the chest
  • unusual tiredness or weakness
  • wheezing
Less common
  • Chills
  • difficult or labored breathing
  • fever
  • heart stops
  • no breathing
  • no pulse or blood pressure
  • seizures
  • unconscious

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Abdominal or stomach pain
  • feeling of warmth
  • nausea
  • numbness
  • redness of the face, neck, arms, and occasionally, upper chest
  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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