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Medications for Premenstrual Syndrome

Other names: PMS; PMT; Premenstrual Tension

What is Premenstrual Syndrome:  Premenstrual syndrome (PMS) refers to a wide range of physical or emotional symptoms that typically occur about 5 to 11 days before a woman starts her monthly menstrual cycle. The symptoms usually stop when menstruation begins, or shortly thereafter.

Medications to treat Premenstrual Syndrome

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Pamprin Multi-Symptom Menstrual Relief N N X Add review Rate

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
acetaminophen / pamabrom / pyrilamine N N X 1 review
9.0

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Brand names:  Pamprin Multi-Symptom Menstrual Relief, Pamprin Maximum Pain, Midol PMS Maximum Strength, Premsyn PMS, Menstrual PMS, Menstrual Pain Relief

Drug class: analgesic combinations

For consumers: interactions, side effects

 
LoSeasonique Off Label X N X 3 reviews
4.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Pamprin Maximum Pain N N X Add review Rate

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Vestura Off Label X N X Add review Rate

Generic name: drospirenone / ethinyl estradiol systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Midol PMS Maximum Strength N N X Add review Rate

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Premsyn PMS N N X 1 review
9.0

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
pamabrom N N 1 review
8.0

Generic name: pamabrom systemic

Brand names:  Diurex Water Capsules, Aqua-Ban, Diurex Aquagels

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

 
acetaminophen / caffeine / pyrilamine N N X 1 review
5.0

Generic name: acetaminophen / caffeine / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
drospirenone / ethinyl estradiol Off Label X N X Add review Rate

Generic name: drospirenone / ethinyl estradiol systemic

Brand name:  Vestura

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
Menstrual PMS N N X Add review Rate

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Diurex Water Capsules N N Add review Rate

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

 
ethinyl estradiol / levonorgestrel Off Label X N X 11 reviews
3.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Brand names:  LoSeasonique, Falmina, Chateal, Myzilra, CamreseLo, Kurvelo, Amethia Lo

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
Falmina Off Label X N X Add review Rate

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Chateal Off Label X N X 1 review
3.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Tylenol Women's Menstrual Relief N N X Add review Rate

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Midol Maximum Strength Teen Formula N N X Add review Rate

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Aqua-Ban N N Add review Rate

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

 
Myzilra Off Label X N X Add review Rate

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
CamreseLo Off Label X N X Add review Rate

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Kurvelo Off Label X N X Add review Rate

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Diurex Aquagels N N Add review Rate

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

 
acetaminophen / pamabrom N N X Add review Rate

Generic name: acetaminophen / pamabrom systemic

Brand names:  Tylenol Women's Menstrual Relief, Midol Maximum Strength Teen Formula, Cramp Tabs

Drug class: analgesic combinations

For consumers: interactions, side effects

 
Amethia Lo Off Label X N X Add review Rate

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Cramp Tabs N N X Add review Rate

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

 
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Learn more about Premenstrual Syndrome

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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