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Medications for Premenstrual Syndrome

Other names: PMS; PMT; Premenstrual Tension

About Premenstrual Syndrome

Premenstrual syndrome (PMS) refers to a wide range of physical or emotional symptoms that typically occur about 5 to 11 days before a woman starts her monthly menstrual cycle. The symptoms usually stop when menstruation begins, or shortly thereafter.

Drugs used to treat Premenstrual Syndrome

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Pamprin Multi-Symptom Menstrual Relief Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Midol PMS Maximum Strength Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

ethinyl estradiol / levonorgestrel Off-label 4.5 16 reviews
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Brand names:  LoSeasonique, Falmina, CamreseLo, Kurvelo, Chateal, Amethia Lo, Myzilra …show all

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off-label: Yes

Midol 5.0 3 reviews
OTC N N X

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Pamprin Maximum Pain Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

acetaminophen / pamabrom / pyrilamine 9.0 1 review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Brand names:  Pamprin Multi-Symptom Menstrual Relief, Midol PMS Maximum Strength, Pamprin Maximum Pain, Premsyn PMS, Menstrual PMS, Menstrual Pain Relief …show all

Drug class: analgesic combinations

For consumers: interactions, side effects

Premsyn PMS 9.0 1 review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

acetaminophen / caffeine / pyrilamine 5.0 1 review
OTC N N X

Generic name: acetaminophen / caffeine / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

For professionals: A-Z Drug Facts

LoSeasonique Off-label 4.3 3 reviews
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Falmina Off-label 9.0 1 review
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

pamabrom 8.0 1 review
OTC N N

Generic name: pamabrom systemic

Brand names:  Diurex Water Capsules, Aqua-Ban, Diurex Aquagels

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

Diurex Water Capsules Rate Add review
OTC N N

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

CamreseLo Off-label Rate Add review
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Kurvelo Off-label Rate Add review
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Chateal Off-label 4.0 4 reviews
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Amethia Lo Off-label Rate Add review
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Menstrual PMS Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Myzilra Off-label Rate Add review
Rx X N X

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Midol Teen Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Menstrual Pain Relief Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom / pyrilamine systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Aqua-Ban Rate Add review
OTC N N

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

Diurex Aquagels Rate Add review
OTC N N

Generic name: pamabrom systemic

Drug class: miscellaneous diuretics

For consumers: interactions, side effects

Tylenol Women's Menstrual Relief Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

acetaminophen / pamabrom 5.0 3 reviews
OTC N N X

Generic name: acetaminophen / pamabrom systemic

Brand names:  Midol, Midol Teen, Tylenol Women's Menstrual Relief, Cramp Tabs …show all

Drug class: analgesic combinations

For consumers: interactions, side effects

Cramp Tabs Rate Add review
OTC N N X

Generic name: acetaminophen / pamabrom systemic

Drug class: analgesic combinations

For consumers: interactions, side effects

Learn more about Premenstrual Syndrome

IBM Watson Micromedex

Symptoms and treatments

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.