IV Infiltration
Medically reviewed by Drugs.com. Last updated on Sep 23, 2025.
AMBULATORY CARE:
IV infiltration
happens when fluid or medicine leaks into the tissue around your IV site. This can happen if the IV moves out of your vein or pokes through the vein wall. Some medicines can cause more harm than others. These include chemo, some antibiotics, contrast liquid, or blood pressure medicines.
Common signs and symptoms:
These signs and symptoms may develop at your IV site:
- Fluid leaking
- Sharp or burning pain
- Swelling, firm, or hard skin
- Cool or pale skin
- Blisters or sores
- Numbness or tingling
- Skin stays pale after you press and let go
Seek care immediately if:
- You develop a fever higher than 101ºF (38.3°C).
- Your symptoms get worse.
- You see thick or bloody drainage at the IV site.
- Your skin turns dark red, purple, or black.
- Your sores get worse or your skin starts to peel.
Call your doctor if:
- You have a fever.
- You have questions or concerns about your condition or care.
Medicines
may be given decrease pain or swelling. You may also need medicine to treat what leaked into your tissue.
How to care for your IV site at home:
- Use a cold or warm pack as directed. Your healthcare provider will tell you which to use according to the type of infiltrated fluid.
- Elevate your arm above the level of your heart as directed. This helps decrease swelling and pain. Rest your arm of pillows or soft blankets.
- Do not use soap, lotion, or cream on the area. Ask your provider what to use to clean and cover the area.
Follow up with your doctor or specialist as directed:
You may need to see your doctor each week to have your wound checked. Your doctor may refer you to a hand specialist, wound care specialist, or physical therapist. Write down your questions so you remember to ask them during your visit.
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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.
Further information
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