Generic Name: Tigecycline (tye ge SYE kleen)
Brand Name: Tygacil
Medically reviewed by Drugs.com. Last updated on Aug 31, 2020.
- A larger number of deaths happened in people taking Tygacil (tigecycline) compared to people taking other drugs used to treat infections. The cause of this risk is not known. This medicine is only for use when other drugs cannot be used.
- Some products have maltose in them, which may affect certain glucose tests. False results of glucose tests may cause problems when treating high or low blood sugar. This may lead to long-lasting effects or death. Talk with the doctor about which blood sugar tests are best to use.
Uses of Tygacil:
- It is used to treat bacterial infections.
What do I need to tell my doctor BEFORE I take Tygacil?
- If you are allergic to Tygacil (tigecycline); any part of Tygacil (tigecycline); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have a hole in the GI (gastrointestinal) tract.
This is not a list of all drugs or health problems that interact with Tygacil (tigecycline).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Tygacil (tigecycline) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Tygacil?
- Tell all of your health care providers that you take Tygacil (tigecycline). This includes your doctors, nurses, pharmacists, and dentists.
- Allergic reactions have happened with Tygacil (tigecycline). Rarely, some reactions can be very bad or life-threatening. Talk with the doctor.
- Do not use longer than you have been told. A second infection may happen.
- This medicine may make you sunburn more easily. Use care if you will be in the sun. Tell your doctor if you sunburn easily while taking this drug.
- Do not give to a child younger than 18 years of age unless other drugs cannot be used or have not worked. Talk with the doctor.
- This medicine may change tooth color to yellow-gray brown if taken by children younger than 8 years old, or in the unborn baby if taken during some parts of pregnancy. If this change of tooth color happens, it will not go away. Other tooth problems have also happened. Bone growth may also be affected in these people taking Tygacil (tigecycline). If you have questions, talk with the doctor.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking Tygacil (tigecycline).
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Tygacil) best taken?
Use Tygacil (tigecycline) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of too much acid in the blood (acidosis) like confusion; fast breathing; fast heartbeat; a heartbeat that does not feel normal; very bad stomach pain, upset stomach, or throwing up; feeling very sleepy; shortness of breath; or feeling very tired or weak.
- Feeling very tired or weak.
- Not able to pass urine or change in how much urine is passed.
- Diarrhea is common with antibiotics. Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea.
- Severe and sometimes deadly pancreas problems (pancreatitis) have happened with Tygacil (tigecycline). This could happen at any time during treatment. Signs of pancreatitis include very bad stomach pain, very bad back pain, or very upset stomach or throwing up. Call your doctor right away if you have any of these signs.
- Raised pressure in the brain has happened with drugs like this one. Most of the time, this went back to normal after the drug was stopped. Sometimes, loss of eyesight happened and did not go away even after the drug was stopped. Call your doctor right away if you have a headache or eyesight problems like blurred eyesight, seeing double, or loss of eyesight.
What are some other side effects of Tygacil?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Stomach pain or diarrhea.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
How do I store and/or throw out Tygacil?
- If you need to store Tygacil (tigecycline) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Tygacil (tigecycline), please talk with your doctor, nurse, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Tygacil (tigecycline)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Generic Availability
- Drug class: glycylcyclines
- FDA Alerts (2)
- FDA Approval History