Generic Name: aminophylline (am-in-AHF-ih-lin)
Brand Name: Generic only. No brands available.
Aminophylline is used for:
Treating active symptoms and blockage of airway due to asthma or other lung diseases such as emphysema or bronchitis. It is used in combination with other medicines.
Aminophylline is a xanthine derivative. It works by relaxing the smooth muscle surrounding the bronchial tubes (air passages) of the lungs, allowing the tubes to widen, making breathing easier. Aminophylline improves contraction of the diaphragm (the major breathing muscle).
Do NOT use aminophylline if:
- you are allergic to any ingredient in aminophylline (including ethylenediamine), similar medicines (eg, theophylline), or xanthines (eg, caffeine, chocolate)
- you are using large amounts of other products that contain xanthine (such as chocolate or caffeinated drinks)
- you are taking dipyridamole intravenously (IV) or halothane
Contact your doctor or health care provider right away if any of these apply to you.
Before using aminophylline:
Some medical conditions may interact with aminophylline. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart problems (eg, congestive heart failure, cor pulmonale), an irregular heartbeat, ulcers or a history of ulcers, fluid in the lungs (pulmonary edema), liver problems, fever, viral infection, severe infection (eg, blood infection), thyroid problems, cystic fibrosis, increased acid levels in the body, brain or nerve problems, or seizures (eg, epilepsy)
- if you are in shock
- if you smoke, are stopping or starting smoking, or are exposed to the smoke from cigarettes or marijuana
- if you are in the last 3 months of pregnancy
Some MEDICINES MAY INTERACT with aminophylline. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aminoglutethimide, barbiturates (eg, phenobarbital), beta-blockers (eg, propranolol), carbamazepine, hydantoins (eg, phenytoin), isoproterenol, moricizine, propafenone, rifampin, or sulfinpyrazone because the effectiveness of aminophylline may be decreased
- Allopurinol, cimetidine, disulfiram, enoxacin, estrogen, fluvoxamine, interferon alpha, macrolide antibiotics (eg, clarithromycin, erythromycin), methotrexate, mexiletine, oral contraceptives (birth control pills), pentoxifylline, quinolone antibiotics (eg, ciprofloxacin), tacrine, thiabendazole, ticlopidine, troleandomycin, verapamil, viloxazine, or zileuton because the risk of side effects of aminophylline may be increased
- Ephedrine because side effects such as nausea, nervousness, and trouble sleeping may be increased
- Halothane because the risk of side effects such as irregular heartbeat may be increased
- Ketamine because the risk of seizures may be increased
- Adenosine, benzodiazepines (eg, diazepam, lorazepam), dipyridamole IV, lithium, midazolam, or nondepolarizing muscle relaxants (eg, pancuronium) because effectiveness may be decreased by aminophylline
This may not be a complete list of all interactions that may occur. Ask your health care provider if aminophylline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use aminophylline:
Use aminophylline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Aminophylline is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using aminophylline at home, carefully follow the injection procedures taught to you by your health care provider.
- If aminophylline contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
- If you miss a dose of aminophylline, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use aminophylline.
Important safety information:
- Use of alcohol may increase the risk of side effects of aminophylline. Talk to your doctor before drinking alcohol while you are taking aminophylline.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using aminophylline.
- Carry an identification card at all times that says you are taking this medication.
- Avoid large amounts of caffeine-containing foods and beverages, such as coffee, tea, cocoa, cola drinks, and chocolate.
- Notify your doctor if you develop a new illness, especially if it is accompanied by fever; if a chronic illness becomes worse; if you start or stop smoking cigarettes or marijuana; or if another doctor prescribes a new medication or tells you to stop using a medication that you have already been taking.
- Aminophylline will not stop an asthma attack once one has started. Be sure to always carry appropriate rescue medicine (eg, bronchodilator inhaler) with you in case of an asthma attack.
- If you have more than one doctor, be sure to tell each of your doctors that you are taking aminophylline.
- Diabetes patients - Aminophylline may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
- LAB TESTS, including blood theophylline levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- Use aminophylline with caution in the ELDERLY because they may be more sensitive to its effects.
- Caution is advised when using aminophylline in CHILDREN, especially newborns with kidney problems, because they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking aminophylline, discuss with your doctor the benefits and risks of using aminophylline during pregnancy. Aminophylline is excreted in breast milk. If you are or will be breast-feeding while you are using aminophylline, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of aminophylline:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Mild and temporary changes in behavior; temporary increased urination.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; diarrhea; dizziness; fast breathing; heart rhythm problems or irregular heartbeats; nausea; persistent headache; seizures; sleeplessness; tremors; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; chest pain; confusion; decreased urination; fast or irregular heartbeat; headache; increased thirst; irritability; loss of appetite; muscle pain or tenderness; nausea; nervousness; persistent increased urination; restlessness; seizures; severe or persistent diarrhea; stomach pain; tremors or twitching; vomiting, especially of blood.Proper storage of aminophylline:
Aminophylline is usually handled and stored by a health care provider. If you are using aminophylline at home, store aminophylline as directed by your pharmacist or health care provider. Keep aminophylline out of the reach of children and away from pets.
- If you have any questions about aminophylline, please talk with your doctor, pharmacist, or other health care provider.
- Aminophylline is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take aminophylline or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about aminophylline. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to aminophylline. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using aminophylline.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: methylxanthines
Other brands: Phyllocontin