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Methylxanthines

What are Methylxanthines?

Methylxanthines are a unique class of drug that are derived from the purine base xanthine. Xanthine is produced naturally by both plants and animals. The methylxanthines, theophylline, and dyphylline are used in the treatment of airways obstruction caused by conditions such as asthma, chronic bronchitis, or emphysema. Caffeine (present in coffee) and theobromine (present in chocolate) are also methylxanthines.

Theophylline is the most well known and most commonly used methylxanthine. At low dosages, it has an immunomodulatory, anti-inflammatory and bronchoprotective effect. Higher dosages are needed for its bronchodilator effect; however, higher dosages are often associated with toxicity.

Experts are not sure exactly how methylxanthines work but research has shown they inhibit the enzyme phosphodiesterase, antagonize adenosine receptors, and at lower dosages, their effects on histone deacetylase activity are believed to contribute to their immunomodulatory effects.

The main role of theophylline and dyphylline is to help maintain good airway control in chronic, persistent, airways disease.

List of Methylxanthines:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Theo-24 (Pro)
generic name: theophylline
2 reviews
   
9.5
Uniphyl (Pro)
generic name: theophylline
3 reviews
   
9.5
Theo-Dur
generic name: theophylline
0 reviews
   
8.0
Quibron-T (Pro)
generic name: theophylline
1 review
   
1.0
Dilor
generic name: dyphylline
0 reviewsAdd rating
Dilor-400
generic name: dyphylline
0 reviewsAdd rating
Dylix
generic name: dyphylline
0 reviewsAdd rating
Elixophyllin (Pro)
generic name: theophylline
0 reviewsAdd rating
Lufyllin (Pro)
generic name: dyphylline
0 reviewsAdd rating
Lufyllin-400
generic name: dyphylline
0 reviewsAdd rating
Phyllocontin
generic name: aminophylline
0 reviewsAdd rating
Quibron-T / SR (Pro)
generic name: theophylline
0 reviewsAdd rating
Theo-Time
generic name: theophylline
0 reviewsAdd rating
TheoCap
generic name: theophylline
0 reviewsAdd rating
Theochron
generic name: theophylline
0 reviewsAdd rating
Theolair
generic name: theophylline
0 reviewsAdd rating
Truxophyllin
generic name: theophylline
0 reviewsAdd rating

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with methylxanthines:

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