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Methylxanthines

What are Methylxanthines?

Methylxanthines are a unique class of drug that are derived from the purine base xanthine. Xanthine is produced naturally by both plants and animals. The methylxanthines, theophylline, and dyphylline are used in the treatment of airways obstruction caused by conditions such as asthma, chronic bronchitis, or emphysema. Caffeine (present in coffee) and theobromine (present in chocolate) are also methylxanthines.

Theophylline is the most well known and most commonly used methylxanthine. At low dosages, it has an immunomodulatory, anti-inflammatory and bronchoprotective effect. Higher dosages are needed for its bronchodilator effect; however, higher dosages are often associated with toxicity.

Experts are not sure exactly how methylxanthines work but research has shown they inhibit the enzyme phosphodiesterase, antagonize adenosine receptors, and at lower dosages, their effects on histone deacetylase activity are believed to contribute to their immunomodulatory effects.

The main role of theophylline and dyphylline is to help maintain good airway control in chronic, persistent, airways disease.

List of Methylxanthines:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Uniphyl (Pro)
Generic name: theophylline
9.5
3 reviews
Theo-24 (Pro)
Generic name: theophylline
9.5
2 reviews
Quibron-T (Pro)
Generic name: theophylline
1.0
2 reviews
Truxophyllin
Generic name: theophylline
No reviews
Theolair
Generic name: theophylline
No reviews
Theochron
Generic name: theophylline
No reviews
TheoCap
Generic name: theophylline
No reviews
Theo-Time
Generic name: theophylline
No reviews
Theo-Dur
Generic name: theophylline
8.0
No reviews
Quibron-T / SR (Pro)
Generic name: theophylline
No reviews
Phyllocontin
Generic name: aminophylline
No reviews
Lufyllin-400
Generic name: dyphylline
No reviews
Lufyllin (Pro)
Generic name: dyphylline
No reviews
Elixophyllin (Pro)
Generic name: theophylline
No reviews
Dylix
Generic name: dyphylline
No reviews
Dilor-400
Generic name: dyphylline
No reviews
Dilor
Generic name: dyphylline
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with methylxanthines:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.