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Creatine use while Breastfeeding

Creatine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Creatine is used as a dietary supplement to increase muscle mass and improve exercise performance. Although creatine is a normal component of human milk, milk levels of creatine have not been measured after exogenous administration in humans. Creatine is converted into creatinine in the mother's and infant's bodies. It may increase the infant's serum creatinine, which may alter estimations of the infant's kidney function.[1] Some authors speculate that creatine supplementation of nursing mothers might help avoid creatine deficiency syndromes, but no studies are available that test this hypothesis.[2] Until more data are available, it is probably best to avoid creatine supplementation unless it is prescribed by a healthcare professional.

Drug Levels

Milk levels of creatine have not been measured after exogenous administration in humans. Creatine is a normal component of human milk.

Maternal Levels. One study found the concentration of creatine to average 25.8 mg/L in normal mothers 3 to 5 days postpartum (n = 3), 18.7 mg/L in mothers 6 to 14 days postpartum (n = 16), and 11.5 mg/L in individual mothers over 15 days postpartum (n = 16). The creatine concentration was 10.1 mg/L in pooled milk from mothers over 15 days postpartum (n = 10).[1]

The creatine concentration in the breastmilk of 3 women was measured. The average concentration was 113 mg/L.[3] Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1. Hulsemann J, Manz F, Wember T, Schoch G. [Administration of creatine and creatinine with breast milk and infant milk preparations]. Klin Padiatr. 1987;199:292-5. PMID: 3657037

2. Wallimann T, Tokarska-Schlattner M, Schlattner U. The creatine kinase system and pleiotropic effects of creatine. Amino Acids. 2011;40:1271-96. PMID: 21448658

3. Peral MJ, Galvez M, Soria ML, Ilundain AA. Developmental decrease in rat small intestinal creatine uptake. Mech Ageing Dev. 2005;126:523-30. PMID: 15722111

Creatine Identification

Substance Name

Creatine

CAS Registry Number

57-00-1

Drug Class

Complementary Therapies

Administrative Information

LactMed Record Number

937

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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