Cascara Sagrada use while Breastfeeding
Drugs containing Cascara Sagrada: Natures Remedy, Caroid Laxative
Cascara Sagrada Levels and Effects while Breastfeeding
Summary of Use during Lactation
Maternal cascara intake might cause loose stools in some breastfed infants and should be avoided. Other laxatives are preferred.
After administration of 65 mg of cascara sagrada as cascara fluidextract, cascara was qualitatively detected in the breastmilk of 5 of 10 women collected over 20 hours. The sensitivity of the assay was about 1100 mg/L of cascara.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
In 2 uncontrolled studies, a total of 10 of 22 breastfed neonates appeared to have loose stools after administration of 65 mg of cascara as cascara fluidextract to their mothers.
In an observational case series, no cases of diarrhea were observed among the breastfed infants of 142 mothers who received 400 mg of cascara extract on day 3 postpartum. This result might have been because of the small amount of colostrum received by the infants of this age.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
1. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852
2. Tyson RM, Shrader EA, Perlman HH. Drugs transmitted through breast milk. Part I: laxatives. J Pediatr. 1937;11:824-32.
3. Duncan AS. Standardized senna as a laxative in the puerperium. A clinical assessment. Br Med J. 1957;1:439-41. PMID: 13396280
Cascara Sagrada Identification
CAS Registry Number
LactMed Record Number
Last Revision Date
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.