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FDA Clears Expanded Use of Cooling Cap to Reduce Hair Loss During Chemotherapy

Posted 19 days ago by Drugs.com

July 3, 2017 – Today, the U.S. Food and Drug Administration cleared the expanded use of a cooling cap, DigniCap Cooling System, to reduce hair loss (alopecia) during chemotherapy. This is the first cooling cap cleared by the agency for use in cancer patients with solid tumors. “We are pleased to expand the use of this product for cancer patients with solid tumors to potentially minimize chemotherapy-induced hair loss,” said Binita Ashar, M.D., director, Division of Surgical Devices, in the FDA’s Center for Devices and Radiological Health. “Managing the side effects of chemotherapy is a critical component to overall health and quality of life.” Hair loss is a common side effect of certain types of chemotherapy and is commonly associated with the treatment of most solid tumor cancer. Hair may fall out entirely, gradually, in sections, or may become thin. Hair loss due to cancer treatmen ... Read more

Related support groups: Taxotere, Docetaxel, Solid Tumors, Idamycin, Idamycin PFS, Idarubicin, Docefrez

'Couch Potatoes' May Face Higher Risk of Kidney, Bladder Cancers

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – Add greater risk of kidney and bladder cancer to the long list of why a lifetime of sitting on the sofa isn't good for your health, a new study suggests. Specifically, lifetime recreational inactivity was associated with a 73 percent increased risk of bladder cancer and a 77 percent increased risk of kidney cancer. The findings add to growing evidence that inactivity may be a significant risk factor for cancer, the researchers said. "We hope that findings like ours will motivate inactive people to engage in some form of physical activity," said study senior author Kirsten Moysich. She is a professor of oncology at Roswell Park Cancer Institute in Buffalo, N.Y. "You don't have to run marathons to reduce your cancer risk, but you have to do something – even small adjustments like taking the stairs instead of the elevator, walking around the block a couple of ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Renal Failure, Renal Cell Carcinoma, Chronic Kidney Disease, Bladder Cancer, Solid Tumors, Urothelial Carcinoma

FDA Approves Keytruda (pembrolizumab) as First Cancer Treatment for any Solid Tumor with a Specific Genetic Feature

Posted 25 May 2017 by Drugs.com

May 23, 2017 – The U.S. Food and Drug Administration today granted accelerated approval to a treatment for patients whose cancers have a specific genetic feature (biomarker). This is the first time the agency has approved a cancer treatment based on a common biomarker rather than the location in the body where the tumor originated. Keytruda (pembrolizumab) is indicated for the treatment of adult and pediatric patients with unresectable or metastatic solid tumors that have been identified as having a biomarker referred to as microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR). This indication covers patients with solid tumors that have progressed following prior treatment and who have no satisfactory alternative treatment options and patients with colorectal cancer that has progressed following treatment with certain chemotherapy drugs. “This is an important f ... Read more

Related support groups: Keytruda, Pembrolizumab, Solid Tumors

Survival Continues to Improve for Most Cancers

Posted 31 Mar 2017 by Drugs.com

FRIDAY, March 31, 2017 – Overall cancer death rates in the United States continue to fall, but racial gaps persist, a new report says. Death rates fell between 2010 and 2014 for 11 of the 16 most common cancers in men and for 13 of the most common types in women, including lung, colon, prostate and breast cancers. However, death rates rose for cancers of the liver, pancreas and brain in men and for the liver and uterus in women. And improvements in cancer survival weren't equal for all Americans. "While this report found that five-year survival for most types of cancer improved among both blacks and whites over the past several decades, racial disparities for many common cancers have persisted, and they may have increased for prostate cancer and female breast cancer," said Dr. Lynne Penberthy. She's associate director of the U.S. National Cancer Institute's Surveillance Research ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Renal Cell Carcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Melanoma, Pancreatic Cancer, Skin Cancer, Ovarian Cancer, Osteosarcoma, Endometrial Cancer, Small Cell Lung Cancer, Breast Cancer - Adjuvant, Bladder Cancer, Cervical Cancer, Melanoma - Metastatic

Zejula Approved for Certain Female Cancers

Posted 28 Mar 2017 by Drugs.com

TUESDAY, March 28, 2017 – Zejula (niraparib) has been approved by the U.S. Food and Drug Administration to treat adult women with recurring cancers of the ovaries, fallopian tubes or abdominal wall (peritoneum) whose tumors have shrunk in response to platinum-based chemotherapy. Citing the National Cancer Institute, the FDA said in a news release that more than 22,000 women are expected to be diagnosed with these cancers this year, and more than 14,000 will die of these diseases. Zejula is designed to block an enzyme involved in repairing damaged DNA. The thought is that by blocking this enzyme, cancer cells would die and slow down or stop tumor growth, the FDA said. The drug was evaluated in clinical studies involving 553 people with any of these recurring cancers who had had their tumors shrunk by at least two doses of platinum-based chemotherapy. The average progression-free ... Read more

Related support groups: Cancer, Ovarian Cancer, Zejula, Peritoneal Cancer, Solid Tumors, Niraparib

Another Study Ties Obesity to Certain Cancers

Posted 1 Mar 2017 by Drugs.com

WEDNESDAY, March 1, 2017 – Carrying extra weight increases the risk of a number of cancers, a new review reports. Additional pounds appear to particularly influence the risk of cancers related to the digestive organs or those driven by hormonal abnormalities, according to the review's European authors. The evidence is so strong at this point that important organizations such as the International Agency for Research on Cancer describe "excess body weight as an important cause of cancers," said Susan Gapstur. She's vice president of epidemiology at the American Cancer Society. The new evidence review was led by Maria Kyrgiou, of Imperial College London's Department of Surgery and Cancer. The review found that a jump in a person's body mass index (BMI) of 5 was associated with a higher cancer risk in the esophagus, bone marrow, biliary tract system, pancreas and kidneys. BMI is a rough ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, Colorectal Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Stomach Cancer, Gastric Cancer, Wilms' Tumor, Peritoneal Cancer, Solid Tumors, Insulinoma, Giant Cell Tumor of Bone, Neoplasm of Bone

Cancer Survivors Gain From Web-Based Health Care

Posted 10 Feb 2017 by Drugs.com

FRIDAY, Feb. 10, 2017 – Online- and phone-based health care offers a number of benefits for cancer survivors, British researchers report. The new study looked at previous research on cancer survivors' experiences with online and phone health contacts – what the researchers call telehealth. The review found that patients liked the flexibility and convenience of this method of staying in touch with their care providers because they could do so in a familiar, comfortable setting and with minimum disruption to their lives. The perceived anonymity of telehealth reduced patients' sense of vulnerability and some said they were more comfortable raising concerns in this setting than in face-to-face appointments. Negative aspects of telehealth mentioned by patients included not being able to meet their health care providers in person, while other patients said they couldn't use the service due ... Read more

Related support groups: Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Skin Cancer, Ovarian Cancer, Small Cell Lung Cancer, Bladder Cancer, Cervical Cancer, Stomach Cancer, Breast Cancer, Prevention, Head and Neck Cancer, Breast Cancer - Palliative, Testicular Cancer, Zollinger-Ellison Syndrome, Wilms' Tumor, Solid Tumors

Benign 'Toothlet' Tumor Found in 255 Million-Year-Old Fossil

Posted 8 Dec 2016 by Drugs.com

THURSDAY, Dec. 8, 2016 – A fossil of a distant ancestor of today's mammals – which include humans – shows evidence of a benign tumor of the jaw, scientists report. The finding pushes back by hundreds of millions of years the advent of these "toothlet" tumors, called odontomas, says a team from the University of Washington in Seattle. The researchers discovered the compound odontoma tumor in the fossilized jaw of a gorgonopsian, a precursor to mammals that lived 255 million years ago. The fossil was unearthed in Tanzania in 2007. Previously, the earliest known evidence of odontomas was in fossils of creatures living less than 1 million years ago. According to the research team, gorgonopsian were distant mammal relatives and the top predators in the pre-dinosaur Permian era when they existed. These animals ranged in size from 2 feet to 10 feet in length, and were known as the "saber ... Read more

Related support groups: Cancer, Head and Neck Cancer, Solid Tumors

Worldwide Cancer Rates Up More Than One-Third in Past Decade: Report

Posted 4 Dec 2016 by Drugs.com

SATURDAY, Dec. 3, 2016 – Cancer cases rose 33 percent worldwide in the past 10 years, a new study shows. In 2015, there were 17.5 million diagnoses and 8.7 million deaths in the world from the disease, the researchers found. The rise in cancer cases was mainly due to population aging and growth, along with changes in age-specific cancer rates, according to the Global Burden of Disease Cancer Collaboration study. The lifetime risk of developing cancer was one in three for men and one in four for women, the researchers said. Prostate cancer was the most common type of cancer in men (1.6 million cases), and tracheal, bronchus and lung cancer was the leading cause of cancer death in men. Breast cancer was the most common cancer for women (2.4 million cases), and the leading cause of cancer death in women. The most common cancers in children were leukemia, other neoplasms, non-Hodgkin ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Lymphoma, Melanoma, Skin Cancer, Ovarian Cancer, Cervical Cancer, Head and Neck Cancer, Testicular Cancer, Salivary Gland Cancer, Solid Tumors

Archeological Finds Push First Known Cancer Back 2 Million Years

Posted 29 Jul 2016 by Drugs.com

FRIDAY, July 29, 2016 – Researchers report that they have unearthed the earliest evidence of bone tumors and cancers, dating back almost 2 million years. The discoveries challenge the belief that cancer is a disease of modern life, the study authors said. "Modern medicine tends to assume that cancers and tumors in humans are diseases caused by modern lifestyles and environments. Our studies show the origins of these diseases occurred in our ancient relatives millions of years before modern industrial societies existed," said researcher Edward Odes. He is a doctoral candidate at the University of the Witwatersrand (Wits) in Johannesburg, South Africa. First, a 1.7-million-year-old foot bone with cancer was found at the Swartkrans cave in South Africa. The exact species is unknown, but it is a hominin, or bipedal human relative, the researchers said. Scientists also found a benign tumor ... Read more

Related support groups: Cancer, Osteosarcoma, Diagnosis and Investigation, Osteolytic Bone Metastases of Solid Tumors, Solid Tumors, Osteogenic Sarcoma

Cancer Patients, Doctors Often Disagree About Prognosis

Posted 15 Jul 2016 by Drugs.com

FRIDAY, July 15, 2016 – Cancer patients and their doctors often hold different opinions about the patient's chances for survival and how long he or she might live, according to a new study. And, in many cases, patients are unaware there's any misunderstanding. "First, some patients might know the doctor's prognosis estimate but the patient chooses to disagree, often because they believe other sources. And second, some patients think that their doctor agrees with their opinion about prognosis but, in fact, the doctor doesn't," said study co-author Dr. Ronald Epstein. He is a professor of family medicine, psychiatry and oncology at the University of Rochester Medical Center in New York. For the study, researchers asked 236 patients with advanced cancer about their prognosis. The 38 doctors who treated them independently said they would "not have been surprised" if their patients died ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Brain Tumor, Melanoma, Ovarian Cancer, Melanoma - Metastatic, Cervical Cancer, Stomach Cancer, Head and Neck Cancer, Testicular Cancer, Solid Tumors

Weight Loss Might Reduce Cancer Risk: Study

Posted 14 Jul 2016 by Drugs.com

THURSDAY, July 14, 2016 – Overweight and obese women who lose weight may lower their odds of developing cancer as their levels of cancer-linked proteins drop, a new study suggests. These proteins – VEGF, PAI-1 and PEDF – promote the growth of blood vessels, a process that is necessary to help tumors thrive. The more weight the women lost, the greater the drop in the levels of these proteins, the researchers found. "It's another piece of evidence in the jigsaw of the benefits of losing weight, and how important weight loss is to prevent cancer," said lead researcher Catherine Duggan. She is a principal staff scientist in the public health sciences division of the Fred Hutchinson Cancer Research Center in Seattle. In general, losing weight reduces the risk of breast, colon and prostate cancer by as much as 20 percent, she said. This might be due to a reduction in inflammatory factors ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Solid Tumors

U.S. Cancer Survivors Living Longer

Posted 1 Jul 2016 by Drugs.com

FRIDAY, July 1, 2016 – As the American population ages, more older adults will survive cancer and live with other chronic conditions that will burden the health care system, U.S. government health officials report. "Increasingly, we are seeing the impact of an aging population – fueled by maturing baby boomers – on major diseases, including cancer," said lead researcher Shirley Bluethmann, a cancer prevention fellow at the U.S. National Cancer Institute. In 2016, nearly 62 percent of almost 16 million cancer survivors are aged 65 or older, the researchers said. By 2040, an estimated 73 percent of 26 million cancer survivors will be 65 or older. "This steady and dramatic growth will affect the health care system, and so is sometimes referred to as the 'silver tsunami,' " Bluethmann said. "It not only has implications for older people who are at higher risk for cancer, it also means ... Read more

Related support groups: Cancer, Breast Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Ovarian Cancer, Melanoma - Metastatic, Solid Tumors

Cancer's Heavy Financial Burden

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – Many cancer patients can't afford to see their doctor or take the medications they've been prescribed, a new study finds. And the problem will likely only get worse as the cost of cancer treatments continues to rise, the study authors said. "You can prescribe the best drug in the world, but if patients can't afford it and they can't get it, then it won't be effective," said study author Dr. Greg Knight. He is chief fellow with the University of North Carolina School of Medicine's division of hematology and oncology. "We saw a significant portion of patients in our study who were stretching their prescriptions or not coming to the doctor's office," Knight said in a university news release. The researchers reviewed survey results from nearly 2,000 patients at the N.C. Cancer Hospital in Chapel Hill, N.C. The participants were all 18 and older, and had been ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Gleevec, Lung Cancer, Colorectal Cancer, Votrient, Brain Tumor, Tarceva, Melanoma, Avastin, Nausea/Vomiting - Chemotherapy Induced, Skin Cancer, Ovarian Cancer, Tasigna, Sutent, Endometrial Cancer, Sprycel, Herceptin, Afinitor

Global Recession May Have Contributed to Cancer Deaths

Posted 26 May 2016 by Drugs.com

THURSDAY, May 26, 2016 – The 2008 global economic crisis has been linked to a sharp rise in deaths from cancer, a new study reports. Unemployment and cuts in public health-care spending were associated with more than 260,000 additional cancer deaths by 2010. Most of those deaths – 160,000 – were in the European Union, the researchers said. The study included 70 countries and a total of more than 2 billion people, according to the report published online May 25 in The Lancet. "Cancer is a leading cause of death worldwide, so understanding how economic changes affect cancer survival is crucial," lead author Dr. Mahiben Maruthappu, of Imperial College London, said in a journal news release. "We found that increased unemployment was associated with increased cancer mortality, but that universal health coverage protected against these effects. This was especially the case for treatable ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Brain Tumor, Melanoma, Pancreatic Cancer, Skin Cancer, Ovarian Cancer, Endometrial Cancer, Bladder Cancer, Cervical Cancer, Melanoma - Metastatic, Stomach Cancer, Breast Cancer - Palliative, Testicular Cancer, Gastric Cancer, Peritoneal Cancer

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