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Related terms: Bone Loss

In Mice, a Way for Stem Cells to Build Bone

Posted 31 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 31, 2016 – Researchers say they've found an easy way to spur stem cells to build bone in mice – a discovery that could lead to new treatments for bone disease. The team of scientists from the University of California, San Diego used a naturally occurring molecule called adenosine to prompt human stem cells to regenerate bone tissue. The new tissue helped repair cranial bone defects in the mice. Stem cells can become any type of cell in the body. But directing these cells to become muscle, bone or skin – a process known as differentiation – requires lengthy steps, according to the researchers. Stem-cell-derived tissues can also develop a type of tumor called teratomas – when cells differentiate the wrong way. The research team found that adding adenosine to the stem cell process helped build bone tissue in mice without any teratoma formation. The study was published ... Read more

Related support groups: Osteoporosis, Fracture, bone, Osteopenia, Bone Infection, Osteomyelitis, Diagnosis and Investigation, Osteomalacia

Injected Drug May Help Fight Osteoporosis in Women

Posted 16 Aug 2016 by Drugs.com

TUESDAY, Aug. 16, 2016 – An experimental drug appears to reduce the risk of bone fractures in postmenopausal women with osteoporosis better than a placebo and the currently available drug, a new study finds. In this phase 3 trial funded by the drug's maker, Radius Health, fewer women on the injectable drug abaloparatide had spine fractures (0.58 percent) than women receiving a placebo (4.22 percent) and slightly fewer than those taking a similar injectable drug, teriparatide (Forteo) (0.84 percent). "If this gets approved, and there is no reason to think it won't, this will be the second drug available for the treatment of high-risk osteoporosis," said lead researcher Dr. Paul Miller of the Colorado Center for Bone Research. Forteo has been in use for the past 16 years, he said. Abaloparatide works differently from Forteo and improves bone density more than Forteo, Miller said. Women ... Read more

Related support groups: Osteoporosis, Forteo, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Compression Fracture of Vertebral Column, Teriparatide, Osteomalacia, Prevention of Fractures

Health Tip: Osteoporosis Shouldn't Be Ignored

Posted 17 Jun 2016 by Drugs.com

-- Osteoporosis occurs when the bones lose density and break more easily. Though it's a common problem, osteoporosis shouldn't be ignored. The National Osteoporosis Foundation says possible complications include: Broken bones. Chronic pain. Losing height. A hunched or stooped posture. Reduced mobility, which can result in feeling depressed or lonely. The potential need for nursing home care, such as for a broken hip. Read more

Related support groups: Osteoporosis, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Caltrate 600 with D, Compression Fracture of Vertebral Column, Os-Cal 500 with D, Calcium/Vitamin D, Citracal + D, Osteomalacia, Citracal Petites, Oysco 500 with D, Calcium 600 D, Calcarb with D, Citracal Creamy Bites, Oyster Shell Calcium, Calcet, Dicalphos plus D, Citracal Maximum, Caltro with Vitamin D

Serious Illness Affects Bone Health

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – A critical illness can lead to bone loss, a new study finds. The research included 66 seniors who spent at least 24 hours on a breathing machine in an intensive care unit (ICU). One year after their ICU stay, the patients had 1.6 percent less bone density in their lower spines and 1.2 percent less bone density in their thigh bones than would be expected. This bone loss may increase their risk of fractures, according to study author Neil Orford, ICU director at University Hospital Geelong in Australia, and colleagues. The researchers said critical illness may accelerate bone resorption. This is a process that occurs when bone is broken down, and calcium and other minerals are released into the bloodstream. A year after an ICU stay, the patients' resorption had returned to normal, but they were left with lower bone density, the study showed. The impact of this ... Read more

Related support groups: Infections, Bacterial Infection, Osteoporosis, Fracture, bone, Prevention of Osteoporosis, Osteopenia, Viral Infection, ICU Agitation, Osteomalacia, Prevention of Fractures

Vitamin D Supplements Won't Strengthen Older Women's Bones: Study

Posted 3 Aug 2015 by Drugs.com

MONDAY, Aug. 3, 2015 – High doses of vitamin D do not appear to protect postmenopausal women from the dangers of osteoporosis, new research indicates. "While high-dose vitamin D did indeed increase calcium absorption, the increase was only 1 percent and [it] did not translate into gains in spine, hip or total body bone mineral density," said study author Dr. Karen Hansen. In fact, Hansen, an associate professor of medicine at the University of Wisconsin School of Medicine and Public Health in Madison, noted that she and her colleagues "did not find any benefit of vitamin D, in either high or low dose, on muscle mass, two tests of muscle fitness or fall [risk]." The team reported the results online Aug. 3 in the journal JAMA Internal Medicine. Postmenopausal women face a greater than average risk for developing osteoporosis, according to the U.S. National Institute of Arthritis and ... Read more

Related support groups: Hot Flashes, Menopausal Disorders, Osteoporosis, Postmenopausal Symptoms, Fracture, bone, Atrophic Vaginitis, Prevention of Osteoporosis, Osteopenia, Perimenopausal Symptoms, Dyspareunia, Caltrate 600 with D, Atrophic Urethritis, Compression Fracture of Vertebral Column, Os-Cal 500 with D, Calcium/Vitamin D, Citracal + D, Osteomalacia, Citracal Petites, Vaginal Dryness, Oysco 500 with D

Health Tip: You May Need a Bone Density Test

Posted 4 Jan 2013 by Drugs.com

-- A bone density test measures the amounts of calcium and other minerals in your bones, and how likely you are to develop thin and brittle bones – characteristics of a condition called osteoporosis. The womenshealth.gov website says your doctor should evaluate the following factors before recommending a bone density test: Your age, and whether you have become menopausal. How tall you are and how much you weigh. Whether you are a smoker and drink alcohol. Your family history of a broken hip, particularly among your parents. Medications you take. Whether you have a disorder that increases your risk of osteoporosis. Read more

Related support groups: Osteoporosis, Prevention of Osteoporosis, Osteopenia

Health Tip: Some Prone to Losing Bone Mass

Posted 5 Jul 2011 by Drugs.com

-- Some people are at risk for losing bone mass, but haven't progressed to full-blown osteoporosis. In other words, their bodies break down old bone faster than they can produce new bone. Doctors call this condition osteopenia. The American Academy of Family Physicians says risk factors for osteopenia include: Getting older. Starting menopause before age 45. Having surgery to remove the ovaries before menopause. Getting insufficient physical activity. Drinking too much alcohol, smoking or other use of tobacco. Having an eating disorder. Having an overactive thyroid. Read more

Related support groups: Osteopenia

Americans May Not Consume Enough Calcium: Study

Posted 2 May 2011 by Drugs.com

FRIDAY, April 29 – A new study finds that Americans may not be consuming enough calcium. Researchers analyzed data from 9,475 adults who took part in the National Health and Nutrition Examination Survey of 2003 to 2006 and found that self-reported calcium density was not sufficient to meet recommended levels. Reported calcium supplement use increased with age in both men and women, but median dietary intake among those aged 81 and older was lower by 23 percent among men and by 14 percent among women, compared to those aged 19 to 30. As people age, they consume less food (energy intake) and therefore less calcium. Median energy intake among men was 35 percent lower among those 81 and older (1,733 kcal/d) compared to those ages 19 to 30 (2,668 kcal/d), said the researchers from the University of Connecticut and Yale University. In women, median energy intake was 28 percent lower in the ... Read more

Related support groups: Dietary Supplementation, Tums, Caltrate, Osteopenia, Calcium Carbonate, Titralac, Oyster, Oyster Shell, Os-Cal 500, Os-Cal, Oyster Calcium, Tums E-X, Chooz, Oysco 500, Calcium Liquid Softgel, Oyst Cal 500, Tums Ultra, Cal Oys, Maalox Regular Strength, Rolaids Soft Chew

Breast Cancer Treatment May Lead to Hip Fracture

Posted 7 Feb 2011 by Drugs.com

FRIDAY, Feb. 4 – Middle-aged breast cancer survivors face an increased risk for hip fractures, a condition normally uncommon in women younger than 70, a new study has found. Researchers at Northwestern University in Chicago say that this may be because early menopause caused by breast cancer treatment and the effects of breast cancer drugs could weaken the bones by the time women reach middle age. The finding came from a study of six women who had survived breast cancer and, in their early 50s, were being treated for hip fractures. Most of the women did not have osteoporosis, but they did have lower-than-normal bone mineral density (osteopenia). This suggests that rapid changes in bone architecture caused by chemotherapy, early menopause and adjuvant breast cancer therapy may not be detected on a bone mineral density test, said Dr. Beatrice Edwards, an associate professor of medicine ... Read more

Related support groups: Breast Cancer, Arimidex, Femara, Anastrozole, Letrozole, Aromasin, Osteopenia, Exemestane, Cytoxan, Cyclophosphamide, Doxorubicin, Adriamycin, Teslac, Adriamycin RDF, Cytoxan Lyophilized, Neosar, Adriamycin PFS, Testolactone

Health Tip: Understanding Osteopenia

Posted 29 Oct 2010 by Drugs.com

-- Osteopenia is the medical term for low bone density. A diagnosis indicates you may be at risk of a more severe form of thinning bones called osteoporosis, according to the National Osteoporosis Foundation. If you have osteopenia, it's time to protect your bones from thinning even more. The lower your bone density, the greater your risk of a fracture. The foundation suggests performing weight-bearing exercises, getting plenty of calcium and vitamin D, limiting alcohol intake and avoiding smoking. Some people with osteopenia may need to start taking medication to stabilize or reverse loss of bone mass. They may also require regular doctor visits and bone density tests. Speak to your doctor about what he or she recommends. Read more

Related support groups: Osteopenia

A Little Drink May Be Good for Your Bones

Posted 18 Mar 2009 by Drugs.com

WEDNESDAY, March 18 – Older men and postmenopausal women who have one or two glasses of beer or wine a day appear to have stronger bones than both nondrinkers and heavy drinkers, a new study suggests. Moderate drinking has been associated with decreasing the risk for heart disease, but it also has been linked to increasing the risk for some cancers. And though their study found that beer and wine could be beneficial to bone strength, the researchers cautioned that people need to balance the risks and benefits of alcohol with their individual health concerns. "We were looking at the relationship between different types of alcohol and bone mineral density [BMD] because there is a controversy about how it might affect bone," said lead researcher Katherine L. Tucker, director of the Dietary Assessment and Epidemiology Research Program at the Jean Mayer USDA Human Nutrition Research Center ... Read more

Related support groups: Prevention of Osteoporosis, Osteopenia

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