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Your Biological Clock: Why Some Age Faster Than Others

Posted 9 hours ago by Drugs.com

WEDNESDAY, Sept. 28, 2016 – Some adults age faster biologically than others, and may die early even if they have healthy lifestyles, researchers report. The international team of scientists analyzed DNA in blood samples from more than 13,000 people in the United States and Europe and used an "epigenetic clock" to predict their life spans. The clock calculates the aging of blood and other tissues by tracking a natural process (methylation) that chemically alters DNA over time, the researchers explained. "We discovered that 5 percent of the population ages at a faster biological rate, resulting in a shorter life expectancy," said principal investigator Steve Horvath. He is a professor of human genetics and biostatistics at the University of California, Los Angeles. "Accelerated aging increases these adults' risk of death by 50 percent at any age," Horvath added in a university news ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Hypertension, Smoking, Insulin Resistance, Diabetes Mellitus, Hypertensive Heart Disease

Can Pregnancy Problems Foretell Future Health Risks?

Posted 2 days 4 hours ago by Drugs.com

MONDAY, Sept. 26, 2016 – Some pregnancy complications may signal a higher risk of health problems later in life, according to a heart specialist. High blood pressure (hypertension) or diabetes that develops during pregnancy usually gets better soon after delivery. But women who've had these conditions aren't off the hook, said Dr. Monika Sanghavi, a cardiologist at UT Southwestern Medical Center in Dallas. "These women are at higher risk for developing hypertension, diabetes and cardiovascular disease in the future, and should be followed long term," Sanghavi said in a hospital news release. Up to 6 percent of pregnant women develop diabetes during pregnancy (called gestational diabetes). Meanwhile, about 7 percent of women develop high blood pressure during pregnancy, according to the U.S. National Institutes of Health. "Cardiologists call pregnancy nature's stress test," said ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Obesity, Hypertension, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Gestational Diabetes, Hypertensive Heart Disease, Labor and Delivery including Augmentation

FDA Approves Invokamet XR (Canagliflozin/Metformin Hydrochloride Extended-Release) for the Treatment of Adults with Type 2 Diabetes

Posted 7 days ago by Drugs.com

RARITAN, N.J., September 21, 2016 – Janssen Pharmaceuticals, Inc. (Janssen) announced today the U.S. Food and Drug Administration (FDA) has approved Invokamet XR - a once-daily, fixed-dose combination therapy of canagliflozin and metformin hydrochloride extended-release (XR)—for first-line use as an adjunct to diet and exercise to improve blood glucose control in adults with type 2 diabetes when treatment with the two medications is appropriate.[1] Invokamet XR combines Invokana (canagliflozin), the most prescribed sodium glucose co-transporter 2 (SGLT2) inhibitor, with more than 9 million U.S. prescriptions since launch,[2] and an XR formulation of metformin. Metformin is commonly prescribed as an initial therapy for the treatment of type 2 diabetes. “Invokamet XR offers the convenience of once-daily dosing and provides physicians needed flexibility for tailoring treatment to the needs ... Read more

Related support groups: Diabetes, Type 2, Metformin, Invokana, Canagliflozin, Invokamet, Canagliflozin/metformin

Canada's First Nations People Face Greater Diabetes Risk

Posted 9 days ago by Drugs.com

MONDAY, Sept. 19, 2016 – Diabetes is more widespread among descendants of people who lived in Canada before Europeans arrived than among the general population, a new study shows. About 8 of 10 First Nations people will develop diabetes at a young age, compared to roughly half of all Canadians, the University of Calgary researchers found. More than 2.25 million people in Canada have the blood sugar disease. Researchers hope their findings will lead to new prevention programs. Lifestyle changes, such as a healthy diet and regular exercise, help reduce diabetes risk. "The changes required to achieve these objectives will need buy-in from a wide range of stakeholders. Thus, it will be important to communicate risk in a way that is understood by the general population and by health authorities," the study authors wrote. To gauge Canadians' lifetime risk of diabetes, researchers looked at ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Diagnosis and Investigation

Health Tip: Know Your Family Health History

Posted 12 days ago by Drugs.com

-- Your doctor may have asked you for your family health history, but do you know why? The U.S. Centers for Disease Control and Prevention says a family's health history, spanning at least three generations, can: Help determine your own risk of health conditions, such as cancer, diabetes or heart disease. Your risk of developing a chronic condition is higher if a close family member has had it. You can't affect your family's medical history, but you can affect your own health by not smoking, exercising and by eating healthier foods. Read more

Related support groups: Diabetes, Type 2, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction

Could Fish Oil Fatty Acids Raise a Woman's Risk for Diabetes?

Posted 12 days ago by Drugs.com

FRIDAY, Sept. 16, 2016 – Women who consume high amounts of meat, fish, eggs and other common foods rich in several different types of fatty acids may end up facing a greater risk for type 2 diabetes, a large and long-term French study suggests. The finding is sure to complicate traditional dietary thinking, given the highly touted health benefits often associated with this group of essential nutrients, which includes the omega-3 polyunsaturated acids typically found in fish. "The principal sources of the harmful fatty acids in our study were meat and fish/seafood," said study authors Guy Fagherazzi and Courtney Dow, both epidemiologists with the Center for Research in Epidemiology and Population Health at INSERM in Villejuif, France. The researchers said they believe that people could definitely cut back on their consumption of meat, because many people consume meat in quantities well ... Read more

Related support groups: Diabetes, Type 2, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus

Marriage May Help Diabetics Keep Weight Off

Posted 12 days ago by Drugs.com

FRIDAY, Sept. 16, 2016 – Spouses may be good for more than just love and companionship: A new study suggests married people with type 2 diabetes are less likely to be overweight than single people with the blood sugar disease. The researchers found that diabetic men who lived with their spouses were also less likely to suffer from metabolic syndrome, a combination of related factors including high blood pressure and high blood sugar that boost the risk of heart disease and stroke. For the study, Japanese researchers examined the medical records of 270 patients with type 2 diabetes from 2010 to 2016. The group included 180 married patients (109 men, 71 women) who were living with their spouses, and 90 single patients (46 men and 44 women). The married people had a lower average body mass index (24.5) than the single people (26.5). The index is a measurement of body fat based on height ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Obesity, Hypertension, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance

Severe Obesity and Heart Failure

Posted 12 days ago by Drugs.com

FRIDAY, Sept. 16, 2016 – Severe obesity appears to be an independent risk factor for heart failure, a new study suggests. Researchers from Johns Hopkins University in Baltimore reviewed data from more than 13,000 American adults, average age 54. After accounting for other risk factors such as high blood pressure, high cholesterol and diabetes, the researchers concluded that severe (morbid) obesity was a stand-alone risk factor for heart failure. Heart failure occurs when the heart is weakened and cannot pump blood sufficiently to take care of the body's needs. Severe obesity is defined as having a body mass index of 40 or higher, according to the U.S. Centers for Disease Control and Prevention. Body mass index is a rough estimate of a person's body fat. A BMI of 25 or below is generally considered normal weight. Someone who is 5 feet 9 inches tall would have to weigh 271 pounds or more ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Obesity, Hypertension, High Cholesterol, Heart Failure, Congestive Heart Failure, Left Ventricular Dysfunction

Study Sees Link Between Long Naps, Type 2 Diabetes Risk

Posted 14 days ago by Drugs.com

WEDNESDAY, Sept. 14, 2016 – Could long afternoon naps raise your risk of developing type 2 diabetes? It's possible but not yet proven, according to new research out of Japan. The study found that, compared with short naps or no napping at all, the risk for the blood sugar disease may be 45 percent higher if your naps last an hour or more. But if you nap less than an hour, the risk disappears, the researchers suggested. Dr. Joel Zonszein is director of the Clinical Diabetes Center at Montefiore Medical Center in New York City. He said the possible connection between long daytime naps and a risk for type 2 diabetes is interesting. But, added Zonszein, who had no part in the study, "People need to be aware that this study, and these findings, are just associations or markers of lifestyles rather that the cause of diabetes." The results of the study were to be presented Wednesday at the ... Read more

Related support groups: Diabetes, Type 2, Sleep Disorders, Fatigue

Pilots on Insulin Therapy Can Safely Fly Commercial Planes: Study

Posted 15 days ago by Drugs.com

TUESDAY, Sept. 13, 2016 – Commercial airline pilots on insulin therapy who keep their diabetes under tight control can perform their job without safety concerns, a new British study concludes. In the United States, however, pilots with insulin-dependent diabetes are prohibited from flying commercial aircraft, the researchers said. A concern is that long flights can interrupt eating and treatment routines, and could lead to low blood sugar levels. Two countries, the United Kingdom and Canada, allow people with diabetes treated with insulin to fly commercial aircraft – if they can show they understand their condition and have it under excellent control, according to the study authors. These pilots are overseen by the U.K. Civil Aviation Authority (CAA) and Irish Aviation Authority. "A growing number of insulin-treated pilots have successfully applied for commercial pilots' licenses in ... Read more

Related support groups: Diabetes, Type 2, Insulin, Diabetes, Type 1, Insulin Resistance, Diabetes Mellitus, Abnormal Glucose Tolerance, Intravenous Insulin Drip

Diabetes During Pregnancy Could Pose Harm to Baby

Posted 15 days ago by Drugs.com

TUESDAY, Sept. 13, 2016 – Babies born to women with either diabetes or gestational diabetes – diabetes that arises during pregnancy – are at greater risk for complications at birth, a new study suggests. Those complications can be serious and include low blood sugar, malformations and being born either too large or too small, according to the new Italian study. One obstetrician in the United States wasn't surprised by the findings. "This study validates what we have known for a long time and have stressed to our patients about diabetes," said Dr. Navid Mootabar, chief of obstetrics and gynecology at Northern Westchester Hospital in Mount Kisco, N.Y. "Poorly controlled diabetes can result in poor outcomes during a pregnancy," he said. For the study, a team led by Dr. Basilio Pintuadi, with the Niguarda Ca' Granda Hospital in Milan, analyzed the delivery outcomes of pregnant women with ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Insulin Resistance, Delivery, Diabetes Mellitus, Premature Labor, Gestational Diabetes, Abnormal Glucose Tolerance, Cesarean Section, Prematurity/Underweight in Infancy, Labor and Delivery including Augmentation

Many With Diabetes Missing Out on Statins

Posted 16 days ago by Drugs.com

MONDAY, Sept. 12, 2016 – Nearly all middle-aged patients with diabetes should be taking cholesterol-lowering statins, but cardiologists fail to prescribe these medications for 2 out of every 5 diabetics in their care, a new study finds. Multiple prior studies have shown that diabetics have a lower risk of heart attack and stroke if they take a statin, even those with no history of heart problems, said senior study author Dr. Salim Virani, a cardiologist at the Michael E. DeBakey VA Medical Center in Houston. "That's not debatable at this point," said Virani, who is also an associate professor at Baylor College of Medicine. "They should all be on statins." But analysis of data from 204 cardiology practices across the United States revealed that 38 percent of middle-aged diabetics have not been prescribed statins. The American College of Cardiology, the American Heart Association and the ... Read more

Related support groups: Diabetes, Type 2, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Pravachol, Prevention of Cardiovascular Disease, Livalo, Red Yeast Rice, Cardiovascular Risk Reduction, Lescol, Mevacor, Lescol XL, Fluvastatin, Pitavastatin, Altoprev

FDA Medwatch Alert: GlucaGen HypoKit (glucagon [rDNA origin] for injection) by Novo Nordisk Inc: Recall - Detached Needles on Syringe

Posted 17 days ago by Drugs.com

ISSUE: Novo Nordisk Inc. is recalling six batches of the GlucaGen HypoKit in the U.S. due to two customer complaints from the UK and Portugal involving detached needles on the syringe with Sterile Water for Injection (SWFI). A syringe with a detached needle cannot be used as prescribed. Untreated hypoglycemia can eventually lead to unconsciousness and seizures, which can prove fatal. If the blood glucose levels are not quickly restored, continuing hypoglycemia can lead to a decline in brain glucose levels which manifests through a variety of symptoms including cognitive dysfunction, sweating, tremors, convulsion and eventually coma or death. This recall includes GlucaGen HypoKit batch numbers: Batch: FS6X270, Expiry: 09/30/2017 Batch: FS6X296, Expiry: 09/30/2017 Batch: FS6X538, Expiry: 09/30/2017 Batch: FS6X597, Expiry: 09/30/2017 Batch: FS6X797, Expiry: 09/30/2017 Batch: FS6X875, ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Hypoglycemia, GlucaGen

Intensive Type 2 Diabetes Treatment Can Extend Survival: Study

Posted 8 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Intensive management of type 2 diabetes can make a difference in how long and how well you live, even if you don't start until middle age, researchers report. People who were already at risk of type 2 diabetes complications were randomly selected to continue with their normal treatment or to be placed in an aggressive and multipronged treatment group. Two decades after the study began, the researchers found that people in the aggressive treatment group lived almost eight years longer. Not only that, they lived better – their risk of heart disease, kidney disease and blindness all dropped. The only complication that didn't seem to improve was nerve damage caused by diabetes. "Early, intensified intervention in type 2 diabetes patients with microalbuminuria with both target-driven pharmacological (medication) and behavioral actions increased life span. And, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Januvia, Glucophage, Novolog, Glipizide, Humalog, Janumet, Byetta, Glyburide, Bydureon, Lantus Solostar, Invokana, Saxenda, Levemir, Actos, Glimepiride

'Glycemic Index' Too Unreliable to Manage Diabetes: Study

Posted 7 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – Glycemic index values of the same foods can vary widely and may be an unreliable indicator of blood sugar response, according to a new study. The glycemic index was created to show how fast blood sugar rises after eating a specific type of food, the study authors said. It's considered a tool to help people with diabetes control their blood sugar levels. In the study, researchers checked blood sugar responses in 63 healthy adults after eating the same amount of white bread three different times over 12 weeks. The investigators found that glycemic index values varied an average of 20 percent among individuals and 25 percent between different study participants. "Glycemic index values appear to be an unreliable indicator even under highly standardized conditions, and are unlikely to be useful in guiding food choices," said lead author Nirupa Matthan. She is a ... Read more

Related support groups: Diabetes, Type 2, Obesity, Weight Loss, Diabetes, Type 1, Insulin Resistance, Vitamin/Mineral Supplementation and Deficiency, Pre-Diabetes, Diabetes Mellitus, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Abnormal Glucose Tolerance

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