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Related terms: Hemoglobin SS disease (Hb SS), Sickle Cell Anemia, Sickle Cell Disease, Hemoglobin SS disease, Hb SS

Endari (L-Glutamine) Supplement May Ease the Pain of Sickle Cell Disease

Posted 19 Jul 2018 by Drugs.com

WEDNESDAY, July 18, 2018 – An FDA-approved supplement reduces episodes of severe pain in people with sickle cell disease, a new clinical trial shows. Endari, a medicine-grade version of the dietary supplement L-glutamine, reduced sickle cell patients' number of acute pain crises by 25 percent compared with a placebo, the researchers found. In addition, the supplement reduced hospitalizations by ...

AHA: New Insights Into Sickle Cell and Stroke Risk

Posted 19 Jun 2018 by Drugs.com

TUESDAY, June 19, 2018 (American Heart Association) – Sickle cell disease increases the risk of stroke for African Americans – but recent research shows carrying the genetic trait for sickle cell doesn't. It's a new layer on the study and treatment of these inherited conditions affecting red blood cells, and experts say it should prompt doctors to dig deeper. Past studies have suggested there ...

FDA Approves Endari (L-glutamine oral powder) for Sickle Cell Disease

Posted 3 May 2018 by Drugs.com

July 7, 2017 – The U.S. Food and Drug Administration today approved Endari (L-glutamine oral powder) for patients age five years and older with sickle cell disease to reduce severe complications associated with the blood disorder. "Endari is the first treatment approved for patients with sickle cell disease in almost 20 years," said Richard Pazdur, M.D., acting director of the Office of ...

Kids Who Need Sickle Cell Antibiotics Don't Always Get Them

Posted 16 Feb 2018 by Drugs.com

FRIDAY, Feb. 16, 2018 – Less than a fifth of U.S. children with sickle cell anemia are getting the antibiotics that could save their lives, a new study finds. "Longstanding recommendations say children with sickle cell anemia should take antibiotics daily for their first five years of life," the study's lead author, Sarah Reeves, said in a news release from Michigan Medicine. These antibiotics ...

FDA Approves New Drug, Endari, for Sickle Cell Disease

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – The U.S. Food and Drug Administration on Friday approved the first new drug for sickle cell disease in nearly two decades. Endari (L-glutamine oral powder) helps reduce severe complications associated with the blood disorder, the agency said. Sickle cell disease is an inherited disorder in which the red blood cells are shaped like a sickle, which limits the flow of vital ...

Sickle Cell Trait Tied to Higher Kidney Failure Risk for Blacks

Posted 9 Mar 2017 by Drugs.com

THURSDAY, March 9, 2017 – Black people with a trait for sickle cell anemia appear to have double the risk of kidney failure that requires dialysis, new research suggests. "Although you cannot change the genes you are born with, doctors can use this information to start screening for kidney disease earlier and to aggressively treat any other risk factors you may have such as diabetes or high ...

Gene Therapy: A Breakthrough for Sickle Cell Anemia?

Posted 2 Mar 2017 by Drugs.com

WEDNESDAY, March 1, 2017 – Researchers are reporting early success using gene therapy to treat, or even potentially cure, sickle cell anemia. The findings come from just one patient, a teenage boy in France. But more than 15 months after receiving the treatment, he remained free of symptoms and his usual medications. That's a big change from his situation before the gene therapy, according to ...

Sickle Cell Trait in Blacks Can Skew Diabetes Test Results

Posted 7 Feb 2017 by Drugs.com

TUESDAY, Feb. 7, 2017 – A blood test commonly used to diagnose and treat diabetes may be less accurate in black people who have the sickle cell anemia trait, a new study says. The test is called hemoglobin A1C (HbA1C). An A1C reading of 5.7 or more indicates prediabetes or diabetes; below 5.7 is normal, says the American Diabetes Association. But, the current study found that for blacks with a ...

New Drug Might Reduce Sickle Cell Pain Crises

Posted 4 Dec 2016 by Drugs.com

SATURDAY, Dec. 3, 2016 – An experimental drug may help reduce episodes of pain associated with sickle cell disease, a new study finds. Results of an early trial showed the drug – called SelG1 for now – reduced episodes of sickle cell-related pain crises by 45 percent. In addition, the drug appeared safe and was well-tolerated, researchers say. "Patients with sickle cell disease have ...

Sickle Cell Trait Not Linked to Early Death in Study

Posted 3 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 3, 2016 – New research challenges the long-held belief that people with sickle cell trait, who are born with only a single copy of the sickle cell gene variant, are at risk of premature death. People with the sickle cell gene variant do not have sickle cell disease, a blood disorder that shortens life span and causes sudden episodes of severe pain. People with the disease carry ...

Drug Protects Lung Function in Kids With Sickle Cell: Study

Posted 18 May 2016 by Drugs.com

WEDNESDAY, May 18, 2016 – Children with sickle cell disease may breathe easier when they're given hydroxyurea – an effective, but underused, drug for the disease, new research suggests. In a study of 94 young people with sickle cell, researchers found that hydroxyurea helped slow the decline in lung function that is typical of the disease. The study appears to be the first to show that ...

Sickle Cell Drug Doesn't Relieve Pain Crises: Study

Posted 8 Dec 2015 by Drugs.com

TUESDAY, Dec. 8, 2015 – The anti-clotting drug prasugrel does little to reduce the risk of pain crises in children with sickle cell disease, a new study shows. The research included 341 patients in 13 countries in Africa, the Americas, Asia, Europe and the Middle East. About half took prasugrel (Effient) for between nine and 24 months. The other half took a placebo. There was little difference ...

Health Tip: Recognizing Signs of Anemia

Posted 18 Jun 2015 by Drugs.com

-- Anemia occurs when there are insufficient red blood cells, or they don't function properly. The American Society of Hematology says warning signs include: Feeling weak or dizzy. Having colder hands and feet. Having pale skin or a yellow tint. Feeling short of breath. Having an irregular or fast heartbeat. Hearing a whooshing sound or pounding in the ears. Having frequent chest pain or ...

Woman Gives Birth Using Ovary Tissue Frozen in Childhood

Posted 10 Jun 2015 by Drugs.com

WEDNESDAY, June 10, 2015 – In what researchers are hailing as a medical breakthrough, a 27-year-old woman gave birth to a healthy baby conceived from ovarian tissue that had been surgically removed and frozen when she was a child. Although this procedure has been used in adults, it wasn't clear if freezing immature ovarian tissue would be able to successfully restore fertility later. The ...

Few Sickle Cell Patients Receiving Beneficial Drug, Study Finds

Posted 28 Apr 2015 by Drugs.com

TUESDAY, April 28, 2015 – Few U.S. adults with sickle cell anemia are getting a recommended medication that can help them manage pain, breathing problems and other debilitating symptoms, according to a new study. Using a national database, researchers found that less than one-quarter of sickle cell patients who should have been taking a drug called hydroxyurea actually were. "This is a ...

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