Vexol Side Effects

Generic Name: rimexolone ophthalmic

Note: This page contains side effects data for the generic drug rimexolone ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Vexol.

It is possible that some side effects of Vexol may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to rimexolone ophthalmic: ophthalmic suspension

As well as its needed effects, rimexolone ophthalmic (the active ingredient contained in Vexol) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking rimexolone ophthalmic, check with your doctor or nurse as soon as possible:

Less common or rare
  • Blurred vision or other change in vision
  • eye discharge, discomfort, dryness, or tearing
  • eye redness, irritation, or pain
  • feeling of something in the eye
  • itching
  • sore throat
  • stuffy or runny nose
  • swelling of the lining of the eyelids

Some rimexolone ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare
  • Browache
  • change in taste
  • crusting in corner of eye
  • dizziness, lightheadedness, or faintness
  • headache
  • increased sensitivity of eyes to light
  • sticky sensation of eyelids
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rimexolone ophthalmic: ophthalmic suspension

Ocular

Ocular side effects have included blurred vision, discharge, ocular pain and discomfort, increased intraocular pressure, foreign body sensation, pruritus, and hyperemia in 1% to 5% of patients. Dry eye, tearing, conjunctival and corneal edema, keratitis, photophobia, corneal erosion, corneal ulcer, corneal staining, increased fibrin, tearing, photophobia, edema, irritation, browache, lid margin crusting, and infiltrate have been reported in less than 1% of patients. In addition, prolonged use of rimexolone ophthalmic (the active ingredient contained in Vexol) solution (and other ophthalmic corticosteroids) has caused ocular hypertension/glaucoma, optic nerve damage, defects in visual acuity and fields of vision, posterior subcapsular cataract formation, and secondary infections of the eye. The use of topical corticosteroids has caused perforation of the globe where there is preexisting thinning of the cornea or sclera.[Ref]

Nervous system

Nervous system side effects have included headache in less than 2% of patients.[Ref]

Respiratory

Respiratory side effects have included rhinitis and pharyngitis in less than 2% of patients.[Ref]

Cardiovascular

Cardiovascular side effects have included hypotension in less than 2% of patients.[Ref]

Other

Other side effects have included taste perversion in less than 2% of patients.[Ref]

References

1. Leibowitz HM, Bartlett JD, Rich R, Mcquirter H, Stewart R, Assil K "Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids." Arch Ophthalmol 114 (1996): 933-7

2. "Product Information. Vexol (rimexolone ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

3. Foster CS, Alter G, Debarge LR, Raizman MB, Crabb JL, Santos CI, Feiler LS, Friedlaender MH "Efficacy and safety of rimexolone 1% ophthalmic suspension vs 1% prednisolone acetate in the treatment of uveitis." Am J Ophthalmol 122 (1996): 171-82

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