Vexol Side Effects

Generic Name: rimexolone ophthalmic

Note: This document contains side effect information about rimexolone ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Vexol.

Some side effects of Vexol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to rimexolone ophthalmic: ophthalmic suspension

Along with its needed effects, rimexolone ophthalmic (the active ingredient contained in Vexol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking rimexolone ophthalmic:

Less common or rare
  • Blurred vision or other change in vision
  • eye discharge, discomfort, dryness, or tearing
  • eye redness, irritation, or pain
  • feeling of something in the eye
  • itching
  • sore throat
  • stuffy or runny nose
  • swelling of the lining of the eyelids

Some side effects of rimexolone ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare
  • Browache
  • change in taste
  • crusting in corner of eye
  • dizziness, lightheadedness, or faintness
  • headache
  • increased sensitivity of eyes to light
  • sticky sensation of eyelids
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rimexolone ophthalmic: ophthalmic suspension


Ocular side effects have included blurred vision, discharge, ocular pain and discomfort, increased intraocular pressure, foreign body sensation, pruritus, and hyperemia in 1% to 5% of patients. Dry eye, tearing, conjunctival and corneal edema, keratitis, photophobia, corneal erosion, corneal ulcer, corneal staining, increased fibrin, tearing, photophobia, edema, irritation, browache, lid margin crusting, and infiltrate have been reported in less than 1% of patients. In addition, prolonged use of rimexolone ophthalmic (the active ingredient contained in Vexol) solution (and other ophthalmic corticosteroids) has caused ocular hypertension/glaucoma, optic nerve damage, defects in visual acuity and fields of vision, posterior subcapsular cataract formation, and secondary infections of the eye. The use of topical corticosteroids has caused perforation of the globe where there is preexisting thinning of the cornea or sclera.

Nervous system

Nervous system side effects have included headache in less than 2% of patients.


Respiratory side effects have included rhinitis and pharyngitis in less than 2% of patients.


Cardiovascular side effects have included hypotension in less than 2% of patients.


Other side effects have included taste perversion in less than 2% of patients.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.