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Trelstar Side Effects

Generic name: triptorelin

Medically reviewed by Drugs.com. Last updated on Jan 1, 2024.

Note: This document provides detailed information about Trelstar Side Effects associated with triptorelin. Some dosage forms listed on this page may not apply specifically to the brand name Trelstar.

Applies to triptorelin: intramuscular powder for suspension, intramuscular powder for suspension 6 month.

Serious side effects of Trelstar

Along with its needed effects, triptorelin (the active ingredient contained in Trelstar) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking triptorelin:

More common

For children

  • diarrhea
  • loss of appetite
  • nausea
  • stomach pain
  • weakness

Less common

For children

  • anxiety
  • body aches or pain
  • chest tightness
  • chills
  • cough
  • cough producing mucus
  • difficulty with breathing
  • ear congestion
  • fever
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of voice
  • mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness
  • muscle aches and pains
  • nasal congestion
  • runny nose
  • shivering
  • sneezing
  • sore throat
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

For adult men

Incidence not known

For children

  • blurred or loss of vision
  • change in ability to see colors, especially blue or yellow
  • depression
  • difficulty with swallowing
  • disturbed color perception
  • dizziness
  • double vision
  • eye pain
  • halos around lights
  • hives, itching, skin rash
  • nervousness
  • night blindness
  • overbright appearance of lights
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seizures
  • slow or fast heartbeat
  • thoughts of killing oneself

For adult men

Other side effects of Trelstar

Some side effects of triptorelin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For children

  • bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • stuffy or runny nose

For adult men

Less common

For children

  • change in hearing
  • dryness or soreness of the throat
  • ear drainage
  • earache
  • hoarseness
  • itching of the ears
  • pain or tenderness around the eyes and cheekbones
  • tender, swollen glands in the neck
  • voice changes

For adult men

For Healthcare Professionals

Applies to triptorelin: intramuscular powder for injection, intramuscular powder for injection extended release.

General

The most common adverse events were hot flushes, impotence, decreased libido, skeletal pain, and headache.[Ref]

Cardiovascular

Genitourinary

At the beginning of treatment, endometriosis symptoms including pelvic pain and dysmenorrhea are commonly exacerbated due to an initial transient increase in plasma estradiol levels. These symptoms are transient and usually disappear in one to two weeks.[Ref]

Psychiatric

Hematologic

Hepatic

Metabolic

Renal

Respiratory

Musculoskeletal

Nervous system

Other

Dermatologic

Hypersensitivity

Local

Gastrointestinal

Ocular

Oncologic

Tumor flare occurred in 5% or less of patients, usually manifested by an increase in urinary symptoms and metastatic pain.[Ref]

Endocrine

The majority of pituitary apoplexy cases occurred within 2 weeks of the first dose, some within the first hour. In these cases, pituitary apoplexy presented as sudden headache, vomiting, visual changes, ophthalmoplegia, altered mental status, and sometimes cardiovascular collapse. Immediate medical attention has been required.[Ref]

References

1. (2001) "Product Information. Trelstar (triptorelin)." Pharmacia and Upjohn

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Frequently asked questions

Further information

Trelstar side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.