SymlinPen 120 Side Effects
Generic name: pramlintide
Medically reviewed by Drugs.com. Last updated on May 28, 2023.
Note: This document contains side effect information about pramlintide. Some dosage forms listed on this page may not apply to the brand name SymlinPen 120.
Applies to pramlintide: subcutaneous solution.
Warning
Subcutaneous route (Solution)
Severe hypoglycemia has occurred within 3 hours of pramlintide injection when used concomitantly with insulin, especially in patients with type 1 diabetes. Serious injuries may happen if hypoglycemia occurs during high-risk activities, and appropriate patient selection, instruction, and insulin dose reduction are critical for reducing this risk.
Serious side effects of SymlinPen 120
Along with its needed effects, pramlintide (the active ingredient contained in SymlinPen 120) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking pramlintide:
More common
- Anxiety
- blurred vision
- chills
- cold sweats
- coma
- confusion
- cool pale skin
- cough
- depression
- difficulty with swallowing
- dizziness
- fast heartbeat
- headache
- hives, itching, or skin rash
- increased hunger
- nausea
- nightmares
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- seizures
- shakiness
- slurred speech
- tightness in the chest
- unusual tiredness or weakness
Other side effects of SymlinPen 120
Some side effects of pramlintide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Difficulty with moving
- inflicted injury
- loss of appetite
- muscle pain or stiffness
- pain in the joints
- stomach pain
- vomiting
- weight loss
Less common
- Body aches or pain
- congestion
- dryness or soreness of the throat
- fever
- hoarseness
- runny nose
- tender, swollen glands in the neck
- voice changes
For Healthcare Professionals
Applies to pramlintide: subcutaneous solution.
Metabolic
Very common (10% or more): Severe hypoglycemia (up to 16.8%), anorexia (up to 17%)[Ref]
Gastrointestinal
Very common (10% or more): Nausea (up to 48%), vomiting (up to 11%)
Common (1% to 10%): Abdominal pain
Frequency not reported: Slower gastric emptying
Postmarketing reports: Pancreatitis[Ref]
Hypersensitivity
Common (1% to 10%): Allergic reaction[Ref]
Nervous system
Very common (10% or more): Headache
Common (1% to 10%): Dizziness[Ref]
Musculoskeletal
Common (1% to 10%): Arthralgia[Ref]
Respiratory
Common (1% to 10%): Cough, pharyngitis[Ref]
General
The most commonly reported side effects were: nausea, vomiting, and severe hypoglycemia.[Ref]
Local
Postmarketing reports: Injection site reactions[Ref]
Other
Very common (10% or more): Inflicted injury (14%)
Common (1% to 10%): Fatigue[Ref]
More about SymlinPen 120 (pramlintide)
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- Dosage information
- During pregnancy
- Drug class: amylin analogs
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Patient resources
Other brands
SymlinPen 60, Symlin, Symlin Pen
Professional resources
Other brands
Related treatment guides
References
1. Product Information. Symlin (pramlintide). Amphastar Pharmaceuticals Inc. 2005.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
