Medication Guide App

Suprane Side Effects

Generic Name: desflurane

Note: This page contains side effects data for the generic drug desflurane. It is possible that some of the dosage forms included below may not apply to the brand name Suprane.

It is possible that some side effects of Suprane may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to desflurane: inhalation liquid, inhalation solution

As well as its needed effects, desflurane (the active ingredient contained in Suprane) may cause unwanted side effects that require medical attention.

Some desflurane side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Coughing
  • nausea or vomiting
Less common or rare
  • Dizziness
  • headache
  • irritated or red eyes
  • nervousness and restlessness
  • sore throat

For Healthcare Professionals

Applies to desflurane: inhalation liquid


Respiratory side effects including coughing (34%), breathholding (up to 30%), apnea (15%), increased secretions, laryngospasm, oxyhemoglobin desaturation, pharyngitis, increased cough, dyspnea, respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis, and hypoxia have been reported.[Ref]


Gastrointestinal side effects including nausea (27%), vomiting (16%), acute pancreatitis, and abdominal pain have been reported.[Ref]


Cardiovascular side effects including bradycardia, hypertension, nodal arrhythmia, tachycardia, arrhythmia, bigeminy, abnormal electrocardiogram, myocardial ischemia, vasodilation, hemorrhage, cardiac arrest, Torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hypotension,
and myocardial infarct have been reported.[Ref]

Nervous system

Nervous system side effects including increased salivation, agitation, convulsion, and dizziness have been reported.[Ref]


Hepatic side effects including hepatitis, hepatic failure, hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, abnormal hepatic function, liver disorder, increased transaminases, increased alanine aminotransferase, and increased aspartate aminotransferase
have been reported.


General side effects including shock, malignant hyperthermia, asthenia, malaise, headache, and fever have been reported.[Ref]


Ocular side effects including conjunctivitis (conjunctival hyperemia) and ocular icterus have been reported.[Ref]


Metabolic side effects including hyperkalemia, hypokalemia, metabolic acidosis, and increased creatinine phosphokinase have been reported.[Ref]


Musculoskeletal side effects including myalgia and rhabdomyolysis have been reported.[Ref]


Dermatologic side effects including urticaria, erythema, and pruritus have been reported.[Ref]


Hematologic side effects including coagulopathy have been reported.


1. "Product Information. Suprane (desflurane)." Baxter Pharmaceutical Products, Inc, New Providence, NJ.

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