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Suprane Side Effects

Generic Name: desflurane

Note: This page contains side effects data for the generic drug desflurane. It is possible that some of the dosage forms included below may not apply to the brand name Suprane.

It is possible that some side effects of Suprane may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to desflurane: inhalation liquid, inhalation solution

As well as its needed effects, desflurane (the active ingredient contained in Suprane) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking desflurane, check with your doctor or nurse immediately:

More common
  • Bluish lips or skin
  • body aches or pain
  • congestion
  • cough
  • dryness or soreness of the throat
  • fever
  • hoarseness
  • not breathing
  • runny nose
  • tender, swollen glands in the neck
  • tightness in the chest
  • trouble breathing
  • trouble swallowing
  • voice changes
Less common
  • Blurred vision
  • chest pain or discomfort
  • dizziness
  • fast, pounding, or irregular heartbeat or pulse
  • headache
  • lightheadedness, dizziness, or fainting
  • nervousness
  • pounding in the ears
  • slow or irregular heartbeat
  • unusual tiredness
Rare
  • Dark urine
  • difficulty with moving
  • feeling of warmth or heat
  • flushing or redness of the skin, especially on the face and neck
  • general tiredness and weakness
  • joint pain
  • light-colored stools
  • muscle aching or cramping
  • muscle pains or stiffness
  • nausea and vomiting
  • noisy breathing
  • pain or discomfort in the arms, jaw, back, or neck
  • sweating
  • swollen joints
  • upper right abdominal or stomach pain
  • yellow eyes and skin
Incidence not known
  • Abdominal or stomach pain
  • confusion
  • convulsions
  • decreased urine
  • dry mouth
  • increased thirst
  • loss of appetite
  • no blood pressure or pulse
  • numbness or tingling in the hands, feet, or lips
  • stopping of heart
  • unconsciousness
  • weakness or heaviness of the legs

Some desflurane side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common
  • Increased watering of the mouth
  • redness of the white part of the eyes or inside of the eyelids
Rare
  • Anxiety
  • hyperventilation
  • irritability
  • itching skin
  • restlessness
  • shaking
  • trouble sleeping

For Healthcare Professionals

Applies to desflurane: inhalation liquid

Respiratory

Respiratory side effects including coughing (34%), breathholding (up to 30%), apnea (15%), increased secretions, laryngospasm, oxyhemoglobin desaturation, pharyngitis, increased cough, dyspnea, respiratory arrest, respiratory failure, respiratory distress, bronchospasm, hemoptysis, and hypoxia have been reported.[Ref]

Gastrointestinal

Gastrointestinal side effects including nausea (27%), vomiting (16%), acute pancreatitis, and abdominal pain have been reported.[Ref]

Cardiovascular

Cardiovascular side effects including bradycardia, hypertension, nodal arrhythmia, tachycardia, arrhythmia, bigeminy, abnormal electrocardiogram, myocardial ischemia, vasodilation, hemorrhage, cardiac arrest, Torsade de pointes, ventricular failure, ventricular hypokinesia, malignant hypertension, hypotension,
and myocardial infarct have been reported.[Ref]

Nervous system

Nervous system side effects including increased salivation, agitation, convulsion, and dizziness have been reported.[Ref]

Hepatic

Hepatic side effects including hepatitis, hepatic failure, hepatic necrosis, cytolytic hepatitis, cholestasis, jaundice, abnormal hepatic function, liver disorder, increased transaminases, increased alanine aminotransferase, and increased aspartate aminotransferase
have been reported.

General

General side effects including shock, malignant hyperthermia, asthenia, malaise, headache, and fever have been reported.[Ref]

Ocular

Ocular side effects including conjunctivitis (conjunctival hyperemia) and ocular icterus have been reported.[Ref]

Metabolic

Metabolic side effects including hyperkalemia, hypokalemia, metabolic acidosis, and increased creatinine phosphokinase have been reported.[Ref]

Musculoskeletal

Musculoskeletal side effects including myalgia and rhabdomyolysis have been reported.[Ref]

Dermatologic

Dermatologic side effects including urticaria, erythema, and pruritus have been reported.[Ref]

Hematologic

Hematologic side effects including coagulopathy have been reported.

References

1. "Product Information. Suprane (desflurane)." Baxter Pharmaceutical Products, Inc, New Providence, NJ.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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