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Rocuronium Side Effects

It is possible that some side effects of rocuronium may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to rocuronium: parenteral injection

Side effects include:

Skeletal muscle weakness.

For Healthcare Professionals

Applies to rocuronium: intravenous solution

Cardiovascular

Uncommon (0.1% to 1%): Arrhythmia, abnormal electrocardiogram, tachycardia
Rare (0.01% to 0.1%): Hypotension, hypertension
Very rare (less than 0.01%): Circulatory collapse and shock, flushing[Ref]

Dermatologic

Rare (0.01% to 0.1%): Injection site edema, pruritus
Very rare (less than 0.01%): Angioneurotic edema, urticaria, rash, erythematous rash[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, vomiting[Ref]

Hypersensitivity

Very rare (less than 0.01%): Hypersensitivity, anaphylactic reaction, anaphylactoid reaction, anaphylactic shock, anaphylactoid shock[Ref]

Respiratory

Uncommon (0.1% to 1%): Asthma (bronchospasm, wheezing, or rhonchi), hiccup
Very rare (less than 0.01%): Bronchospasm
Postmarketing reports: Increased pulmonary vascular resistance[Ref]

Local

Rare (less than 0.1%): Injection site pain, injection site reaction[Ref]

Musculoskeletal

Rare (less than 0.1%): Prolonged neuromuscular block
Very rare (less than 0.01%): Muscular weakness
Frequency not reported: Residual paralysis, myopathy[Ref]

Nervous system

Very rare (less than 0.01%): Flaccid paralysis[Ref]

Other

Uncommon (0.1% to 1%): Drug ineffective, drug effect/therapeutic response decreased, drug effect/therapeutic response increased
Frequency not reported: Malignant hyperthermia[Ref]

References

1. "Product Information. Zemuron (rocuronium)." Organon, West Orange, NJ.

2. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

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