Skip to Content

Rimexolone ophthalmic Side Effects

For the Consumer

Applies to rimexolone ophthalmic: ophthalmic suspension

As well as its needed effects, rimexolone ophthalmic may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking rimexolone ophthalmic, check with your doctor or nurse as soon as possible:

Less common or rare
  • Blurred vision or other change in vision
  • eye discharge, discomfort, dryness, or tearing
  • eye redness, irritation, or pain
  • feeling of something in the eye
  • itching
  • sore throat
  • stuffy or runny nose
  • swelling of the lining of the eyelids

Some rimexolone ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common or rare
  • Browache
  • change in taste
  • crusting in corner of eye
  • dizziness, lightheadedness, or faintness
  • headache
  • increased sensitivity of eyes to light
  • sticky sensation of eyelids
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rimexolone ophthalmic: ophthalmic suspension


Ocular side effects have included blurred vision, discharge, ocular pain and discomfort, increased intraocular pressure, foreign body sensation, pruritus, and hyperemia in 1% to 5% of patients. Dry eye, tearing, conjunctival and corneal edema, keratitis, photophobia, corneal erosion, corneal ulcer, corneal staining, increased fibrin, tearing, photophobia, edema, irritation, browache, lid margin crusting, and infiltrate have been reported in less than 1% of patients. In addition, prolonged use of rimexolone ophthalmic solution (and other ophthalmic corticosteroids) has caused ocular hypertension/glaucoma, optic nerve damage, defects in visual acuity and fields of vision, posterior subcapsular cataract formation, and secondary infections of the eye. The use of topical corticosteroids has caused perforation of the globe where there is preexisting thinning of the cornea or sclera.[Ref]

Nervous system

Nervous system side effects have included headache in less than 2% of patients.[Ref]


Respiratory side effects have included rhinitis and pharyngitis in less than 2% of patients.[Ref]


Cardiovascular side effects have included hypotension in less than 2% of patients.[Ref]


Other side effects have included taste perversion in less than 2% of patients.[Ref]


1. Leibowitz HM, Bartlett JD, Rich R, Mcquirter H, Stewart R, Assil K "Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids." Arch Ophthalmol 114 (1996): 933-7

2. Foster CS, Alter G, Debarge LR, Raizman MB, Crabb JL, Santos CI, Feiler LS, Friedlaender MH "Efficacy and safety of rimexolone 1% ophthalmic suspension vs 1% prednisolone acetate in the treatment of uveitis." Am J Ophthalmol 122 (1996): 171-82

3. "Product Information. Vexol (rimexolone ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

It is possible that some side effects of rimexolone ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.