Metformin / repaglinide Side Effects

It is possible that some side effects of metformin / repaglinide may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to metformin / repaglinide: oral tablet

As well as its needed effects, metformin / repaglinide may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking metformin / repaglinide, check with your doctor immediately:

More common
  • Anxiety
  • blurred vision
  • body aches or pain
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • cough
  • depression
  • difficulty in breathing
  • dizziness
  • ear congestion
  • fast heartbeat
  • fever
  • headache
  • increased hunger
  • loss of voice
  • nasal congestion
  • nausea
  • nervousness
  • nightmares
  • runny nose
  • seizures
  • shakiness
  • slurred speech
  • sneezing
  • sore throat
  • unusual tiredness or weakness

Some metformin / repaglinide side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Diarrhea
  • vomiting

For Healthcare Professionals

Applies to metformin / repaglinide: oral tablet


Gastrointestinal side effects have included diarrhea, nausea, and vomiting.


Hepatic side effects have included severe hepatic dysfunction including jaundice and hepatitis.


Endocrine side effects have included symptomatic hypoglycemia and pancreatitis.

Nervous system

Nervous system side effects have included headache.


Respiratory side effects have included upper respiratory tract infection.


Hematologic side effects have included hemolytic anemia.


Dermatologic side effects have included alopecia and Stevens-Johnson Syndrome.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.