Ludiomil Side Effects
Generic Name: maprotiline
Note: This page contains side effects data for the generic drug maprotiline. It is possible that some of the dosage forms included below may not apply to the brand name Ludiomil.
It is possible that some side effects of Ludiomil may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to maprotiline: oral tablet
Along with its needed effects, maprotiline (the active ingredient contained in Ludiomil) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking maprotiline:More common
- Skin rash, redness, swelling, or itching
- Constipation (severe)
- nausea or vomiting
- shakiness or trembling
- seizures (convulsions)
- unusual excitement
- weight loss
- Breast enlargement—in males and females
- confusion (especially in the elderly)
- difficulty in urinating
- hallucinations (seeing, hearing, or feeling things that are not there)
- inappropriate secretion of milk—in females
- irregular heartbeat (pounding, racing, skipping)
- sore throat and fever
- swelling of testicles
- yellow eyes or skin
- Convulsions (seizures)
- dizziness (severe)
- drowsiness (severe)
- fast or irregular heartbeat
- muscle stiffness or weakness (severe)
- restlessness or agitation
- trouble in breathing
Some side effects of maprotiline may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Blurred vision
- decreased sexual ability
- dizziness or lightheadedness (especially in the elderly)
- dryness of mouth
- increased or decreased sexual drive
- tiredness or weakness
- Constipation (mild)
- increased appetite and weight gain
- increased sensitivity of skin to sunlight
- increased sweating
- trouble in sleeping
- weight loss
After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:
For Healthcare Professionals
Applies to maprotiline: oral tablet
Gastrointestinal side effects including dry mouth (22%), constipation (6%), and nausea (2%) have been reported. Vomiting, epigastric distress, diarrhea, bitter taste, abdominal cramps, increased salivation, and dysphagia have rarely been reported.
Nervous system side effects including drowsiness (16%), dizziness (8%), and tremor (3%) have been reported. Numbness, tingling, motor hyperactivity, akathisia, seizures, EEG alterations, tinnitus, extrapyramidal symptoms, ataxia, and dysarthria have rarely been reported.
Psychiatric side effects including nervousness (6%), anxiety (3%), insomnia (2%), and agitation (2%) have been reported. Confusion (especially in the elderly), hallucinations, disorientation, delusions, restlessness, nightmares, hypomania, mania, exacerbation of psychosis, decrease in memory, and feelings of unreality have rarely been reported.
General side effects including weakness and fatigue (4%), headache (4%), and drug fever have been reported. Weight loss or gain has rarely been reported.
Ocular side effects including blurred vision (4%) have been reported. Accommodation disturbances and mydriasis have rarely been reported.
Cardiovascular side effects including hypertension, hypotension, tachycardia, edema, arrhythmia, heart block, palpitation, and syncope have rarely been reported.
Genitourinary side effects including urinary retention and delayed micturition have been reported. Urinary frequency has rarely been reported.
Dermatologic side effects including skin rash, petechiae, itching, alopecia, excessive perspiration, flushing, and photosensitization have rarely been reported.
Endocrine side effects including increased or decreased libido, impotence, and elevation or depression of blood sugar levels have rarely been reported.
Hepatic side effects including altered liver function and jaundice have rarely been reported.
Respiratory side effects including several cases of interstitial pneumonitis have been reported. Nasal congestion has rarely been reported.
In some of the cases, the interstitial pneumonitis was associated with eosinophilia and increased liver enzymes. However, no clear causal relationship to maprotiline has been established.
More about Ludiomil (maprotiline)
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