Loratadine Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 3, 2023.

Applies to loratadine: oral capsule liquid filled, oral solution, oral syrup, oral tablet, oral tablet chewable, oral tablet disintegrating.

Serious side effects of loratadine

Along with its needed effects, loratadine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking loratadine:

Incidence not known

• drowsiness

For healthcare professionals

Applies to loratadine: oral capsule, oral syrup, oral tablet, oral tablet chewable, oral tablet disintegrating.

General

The most commonly reported side effects included headache, somnolence nervousness, and fatigue.^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 12%)
• Common (1% to 10%): Sedation/somnolence
• Very rare (less than 0.01%): Dizziness, convulsion
• Frequency not reported: Syncope, paresthesia^[Ref]

Psychiatric

• Common (1% to 10%): Nervousness
• Uncommon (0.1% to 1%): Insomnia
• Frequency not reported: Depression, paroniria^[Ref]

Other

• Common (1% to 10%): Fatigue
• Frequency not reported: Fever, viral infection, tinnitus, malaise^[Ref]

Gastrointestinal

• Common (1% to 10%): Dry mouth
• Very rare (less than 0.01%): Nausea, gastritis
• Frequency not reported: Dyspepsia, diarrhea, constipation, abdominal/gastric pain, altered taste, increased saliva^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Increased appetite^[Ref]

Dermatologic

• Very rare (less than 0.01%): Angioedema, rash, alopecia
• Frequency not reported: Pruritus, rash on face^[Ref]

Genitourinary

• Frequency not reported: Increased frequency of urination, urine discoloration, menstruation delay^[Ref]

Cardiovascular

• Very rare (less than 0.01%): Tachycardia, palpitation
• Frequency not reported: Hypertension, hypotension, chest pain^[Ref]

Hypersensitivity

• Very rare (less than 0.01%): Hypersensitivity reactions, anaphylaxis^[Ref]

Hepatic

• Very rare (less than 0.01%): Abnormal hepatic function^[Ref]

Respiratory

• Frequency not reported: Epistaxis, nasal dryness, pharyngitis, coughing^[Ref]

Musculoskeletal

• Frequency not reported: Myalgia^[Ref]

Frequently asked questions

• What are the most common skin conditions? (with photos)
• Can you give loratadine to dogs?
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• Can you take 10mg of loratadine twice a day?
• Can you take antihistamines when pregnant?

Further information

Loratadine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer