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Ketalar Side Effects

Generic Name: ketamine

Note: This page contains information about the side effects of ketamine. Some of the dosage forms included on this document may not apply to the brand name Ketalar.

Not all side effects for Ketalar may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to ketamine: injection solution

In addition to its needed effects, some unwanted effects may be caused by ketamine (the active ingredient contained in Ketalar). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking ketamine, check with your doctor or nurse immediately:

Incidence not known
  • Bloody or cloudy urine
  • bluish lips or skin
  • blurred vision
  • chest pain or discomfort
  • confusion
  • confusion as to time, place, or person
  • convulsions
  • cough
  • difficult or troubled breathing
  • difficult, burning, or painful urination
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • fast, slow, or irregular heartbeat
  • frequent urge to urinate
  • hives
  • holding false beliefs that cannot be changed by fact
  • irregular, fast or slow, or shallow breathing
  • itching
  • not breathing
  • pale or blue lips, fingernails, or skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seeing, hearing, or feeling things that are not there
  • shortness of breath
  • skin rash
  • sweating
  • tightness in the chest
  • unusual excitement, nervousness, or restlessness
  • unusual tiredness or weakness

Some of the side effects that can occur with ketamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Double vision
  • dream-like state
  • flushing or redness of the skin
  • loss of appetite
  • nausea
  • pain at the injection site
  • seeing double
  • uncontrolled eye movements
  • unusually warm skin
  • vomiting
  • weight loss

For Healthcare Professionals

Applies to ketamine: compounding powder, injectable solution, intravenous solution


Cardiovascular side effects have included elevated blood pressure and pulse rate following administration of ketamine (the active ingredient contained in Ketalar) alone. However, hypotension and bradycardia have been observed. Arrhythmia has also been reported.[Ref]


Respiratory side effects have included stimulated respiration, although severe depression of respiration or apnea may occur following rapid intravenous administration of ketamine (the active ingredient contained in Ketalar) Laryngospasms and other forms of airway obstruction have occurred during ketamine anesthesia.[Ref]


Ocular side effects have included diplopia, nystagmus, and a slight elevation in intraocular pressure.[Ref]


Gastrointestinal side effects have included anorexia, nausea, and vomiting.[Ref]


Musculoskeletal side effects have included enhanced skeletal muscle tone manifested by tonic and clinic movements sometimes resembling seizures.[Ref]


Local side effects have included pain and exanthema at the injection site.[Ref]


Dermatologic side effects have included transient erythema and/or morbilliform rash.[Ref]


Psychiatric side effects have included anxiety, dysphoria, disorientation, insomnia, flashbacks, hallucinations, and psychotic episodes. A withdrawal syndrome with psychotic features has been described following discontinuation of long-term ketamine (the active ingredient contained in Ketalar) use.[Ref]


1. "Product Information. Ketalar (ketamine)." JHP Pharmaceuticals, Saddle River, NJ.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.