Cabergoline Side Effects
Some side effects of cabergoline may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to cabergoline: oral tablet
Get emergency medical help if you have any of these signs of an allergic reaction while taking cabergoline: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using cabergoline and call your doctor at once if you have a serious side effect such as:
feeling short of breath on exertion;
chest discomfort, dry cough or hack;
feeling weak or tired, loss of appetite, rapid weight loss;
feeling like you might pass out;
lower back pain;
urinating less than usual or not at all; or
swelling in your ankles or feet.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking cabergoline.
Less serious side effects of cabergoline may include:
nausea, vomiting, stomach pain, gas, indigestion, constipation;
headache, depressed mood;
dizziness, spinning sensation;
numbness or tingly feeling; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to cabergoline: oral tablet
Gastrointestinal side effects including nausea (10% to 31%), constipation (7% to 10%), abdominal pain (5% to 7%), dyspepsia (2% to 5%), vomiting (2% to 4%), dry mouth (2%), diarrhea (2%), and flatulence (2%), throat irritation (1%), and toothache (1%) have been reported.
Nervous system effects including headache (13% to 30%), dizziness (13% to 25%), postural hypotension (4%), vertigo (1% to 4%), and paresthesia (1% to 2%) have been reported.
Other side effects including fatigue (5% to 13%), asthenia (4% to 9%), somnolence (5%), hot flashes (1% to 3%), syncope (1%), influenza-like symptoms (1%), malaise (1%), periorbital edema (1%), and facial edema (less than 1%) have been reported.
Psychiatric side effects including somnolence (2% to 5%), depression (3%), nervousness (1% to 2%), anorexia (1%), anxiety (1%), insomnia (1%), and impaired concentration (1%) have been reported.
Psychiatric side effects reported during postmarketing surveillance have included aggression and psychotic disorder.
Cardiovascular effects including hypotension (1%), dependent edema (1%), palpitation (1%), and syncope (less than 1%) have been reported. Valvulopathy has been reported following long-term administration of cabergoline. A case of mitral valve regurgitation has also been reported.
Genitourinary side effects including breast pain (1% to 4%), dysmenorrhea (1%) and increased libido (less than 1%) have been reported. A case of recurrent penile erections had also been reported.
Musculoskeletal side effects including pain (2%) and arthralgia (1%) have been reported.
Dermatologic side effects including acne (1%), pruritus (1%), and alopecia have been reported. A case of erythema nodosum has been reported. A case of scalp irritation has also been reported which, (along with facial edema) lead to discontinuation of therapy.
Respiratory side effects including rhinitis (1%), nasal stuffiness (less than 1%), and epistaxis (less than 1%) have been reported. Pleural effusion and pulmonary fibrosis have been reported following long-term administration of cabergoline. A case of progressive pleuropulmonary abnormalities and systemic illness possibly caused by cabergoline has been reported.
Ocular side effects including abnormal vision (1%) have been reported.
Metabolic side effects including both weight loss (less than 1%) and weight gain (less than 1%) have been reported.
Oncologic side effects have been reported in animal studies which showed a slight increase in the incidence of both cervical and uterine leiomyomas as well as uterine leiomyosarcomas in mice. Studies also showed a slight increase in malignant tumors of the cervix and uterus and interstitial cell adenomas in rats.
Endocrine side effects have included recurrence of hyperprolactinemia following withdrawal of long-term cabergoline therapy.
More cabergoline resources
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.