Cabergoline Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hyperprolactinemia

Initial dose: 0.25 mg orally twice a week. Dosage may be increased by 0.25 mg twice a week.

Maximum dose: 1 mg orally twice a week (according to patient serum prolactin level).

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

The manufacturer recommends caution when administering this drug to patients with liver dysfunction (Child-Pugh score greater than 10).

Dose Adjustments

The dosage may be increased by 0.25 mg twice a week up to a maximum dosage of 1 mg twice a week according to the patient's serum prolactin level. Increases in dosage should occur no more rapidly than every 4 weeks.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

If the patient does not respond adequately, and no additional benefit is observed with higher doses, the lowest dose that achieved maximal response should be administered and other therapeutic approaches considered. After a normal serum prolactin level has been maintained for 6 months, the drug may be discontinued with monitoring of the serum prolactin level, to determine whether treatment should be restarted.

Cabergoline may be administered without regard to meals.

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