Generic name: cilostazol 50mg
Dosage form: tablet
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The recommended dosage of PLETAL is 100 mg twice daily taken at least half an hour before or two hours after breakfast and dinner.
A dose reduction to 50 mg twice daily should be considered during co-administration with strong or moderate CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin and diltiazem) and during co‑administration with CYP2C19 inhibitors (e.g., ticlopidine, fluconazole and omeprazole. (see PRECAUTIONS AND Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions)
Patients may respond as early as 2 to 4 weeks after the initiation of therapy, but treatment for up to 12 weeks may be needed before a beneficial effect is experienced. If symptoms are unimproved after 3 months, discontinue Pletal.