Dibenzyline

Generic Name: phenoxybenzamine (fen OX ee BENZ a meen)
Brand Name: Dibenzyline

What is Dibenzyline (phenoxybenzamine)?

Phenoxybenzamine lowers blood pressure.

Phenoxybenzamine is used control blood pressure and reduce sweating in people with pheochromocytoma.

Phenoxybenzamine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Dibenzyline (phenoxybenzamine)?

You should not use this medication if you are allergic to phenoxybenzamine.

Before taking phenoxybenzamine, tell your doctor if you have coronary artery disease, a lung infection, or kidney disease.

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Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my healthcare provider before taking Dibenzyline (phenoxybenzamine)?

You should not use this medication if you are allergic to phenoxybenzamine.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

  • coronary artery disease (hardened arteries);

  • a lung infection; or

  • kidney disease.

FDA pregnancy category C. It is not known whether phenoxybenzamine is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether phenoxybenzamine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Dibenzyline (phenoxybenzamine)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take this medicine with a full glass of water.

Store phenoxybenzamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include fast heart rate, vomiting, dizziness, or fainting.

What should I avoid while taking Dibenzyline (phenoxybenzamine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine.

Dibenzyline (phenoxybenzamine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.

Less serious side effects may include:

  • stuffy nose;

  • mild dizziness or drowsiness;

  • blurred vision;

  • trouble having an orgasm;

  • upset stomach; or

  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Dibenzyline (phenoxybenzamine)?

Tell your doctor about all other medications you use, especially:

  • reserpine;

  • tizanidine (Zanaflex);

  • epinephrine (Epi-Pen), norepinephrine; or

  • blood pressure medications.

This list is not complete and there may be other drugs that can interact with phenoxybenzamine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about phenoxybenzamine.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 3.02. Revision Date: 2010-12-15, 5:01:39 PM.

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