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Medications for Plaque Psoriasis

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
apremilast 5.3 308 reviews for apremilast to treat Plaque Psoriasis
Rx C N
Generic name:
apremilast systemic
Brand name:
Otezla
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Otezla 5.2 291 reviews for Otezla to treat Plaque Psoriasis
Rx C N
Generic name:
apremilast systemic
Drug class:
antirheumatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ixekizumab 7.5 127 reviews for ixekizumab to treat Plaque Psoriasis
Rx N
Generic name:
ixekizumab systemic
Brand name:
Taltz
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Taltz 7.4 125 reviews for Taltz to treat Plaque Psoriasis
Rx N
Generic name:
ixekizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
secukinumab 7.0 116 reviews for secukinumab to treat Plaque Psoriasis
Rx B N
Generic name:
secukinumab systemic
Brand name:
Cosentyx
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Cosentyx 7.1 113 reviews for Cosentyx to treat Plaque Psoriasis
Rx B N
Generic name:
secukinumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
betamethasone / calcipotriene 7.4 59 reviews for betamethasone / calcipotriene to treat Plaque Psoriasis
Rx C N
Generic name:
betamethasone / calcipotriene topical
Brand names:
Taclonex, Enstilar, Taclonex Scalp, Wynzora
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enstilar 7.3 44 reviews for Enstilar to treat Plaque Psoriasis
Rx C N
Generic name:
betamethasone / calcipotriene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
guselkumab 7.9 44 reviews for guselkumab to treat Plaque Psoriasis
Rx N
Generic name:
guselkumab systemic
Brand name:
Tremfya
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Tremfya 7.7 41 reviews for Tremfya to treat Plaque Psoriasis
Rx N
Generic name:
guselkumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adalimumab 5.8 37 reviews for adalimumab to treat Plaque Psoriasis
Rx B N
Generic name:
adalimumab systemic
Brand names:
Humira, Hyrimoz, Abrilada, Amjevita, Cyltezo, Hadlima, Hulio, Idacio, Simlandi, Yuflyma, Yusimry
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Humira 5.8 37 reviews for Humira to treat Plaque Psoriasis
Rx B N
Generic name:
adalimumab systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tapinarof 8.0 32 reviews for tapinarof to treat Plaque Psoriasis
Rx N
Generic name:
tapinarof topical
Brand name:
Vtama
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph
Vtama 8.0 31 reviews for Vtama to treat Plaque Psoriasis
Rx N
Generic name:
tapinarof topical
Drug class:
topical antipsoriatics
For consumers:
dosage, side effects
For professionals:
Prescribing Information
risankizumab 8.0 21 reviews for risankizumab to treat Plaque Psoriasis
Rx N
Generic name:
risankizumab systemic
Brand name:
Skyrizi
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
roflumilast 9.0 21 reviews for roflumilast to treat Plaque Psoriasis
Rx N
Generic name:
roflumilast topical
Brand name:
Zoryve
Drug class:
selective phosphodiesterase-4 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Zoryve 9.0 21 reviews for Zoryve to treat Plaque Psoriasis
Rx N
Generic name:
roflumilast topical
Drug class:
selective phosphodiesterase-4 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Skyrizi 8.1 18 reviews for Skyrizi to treat Plaque Psoriasis
Rx N
Generic name:
risankizumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enbrel 8.3 16 reviews for Enbrel to treat Plaque Psoriasis
Rx B N
Generic name:
etanercept systemic
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
etanercept 8.3 16 reviews for etanercept to treat Plaque Psoriasis
Rx B N
Generic name:
etanercept systemic
Brand names:
Enbrel, Erelzi, Eticovo
Drug class:
antirheumatics, TNF alfa inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
brodalumab 7.7 15 reviews for brodalumab to treat Plaque Psoriasis
Rx N
Generic name:
brodalumab systemic
Brand name:
Siliq
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Duobrii 8.0 14 reviews for Duobrii to treat Plaque Psoriasis
Rx N
Generic name:
halobetasol / tazarotene topical
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
halobetasol / tazarotene 8.0 14 reviews for halobetasol / tazarotene to treat Plaque Psoriasis
Rx N
Generic name:
halobetasol / tazarotene topical
Brand name:
Duobrii
Drug class:
topical antipsoriatics
For consumers:
dosage, interactions, side effects
Siliq 7.5 14 reviews for Siliq to treat Plaque Psoriasis
Rx N
Generic name:
brodalumab systemic
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ustekinumab 8.7 10 reviews for ustekinumab to treat Plaque Psoriasis
Rx B N
Generic name:
ustekinumab systemic
Brand names:
Stelara, Selarsdi, Wezlana
Drug class:
interleukin inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Frequently asked questions

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.