Medication Guide App

Ustekinumab Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Psoriasis

For use in the treatment of patients with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy:

100 kg (220 lbs) or less:
Initial dose: 45 mg subcutaneously once initially and 4 weeks later
Maintenance dose: 45 mg subcutaneously once every 12 weeks

Greater than 100 kg (220 lbs):
Initial dose: 90 mg subcutaneously once initially and 4 weeks later
Maintenance dose: 90 mg subcutaneously once every 12 weeks

In subjects weighing greater than 100 kg, 45 mg was also shown to be effective. However, 90 mg resulted in greater efficacy.

The safety and efficacy of ustekinumab have not been evaluated beyond two years.

Usual Adult Dose for Psoriatic Arthritis

Initial dose: 45 mg subcutaneously once initially and 4 weeks later
Maintenance dose: 45 mg subcutaneously once every 12 weeks

For patients with co-existent moderate-to-severe plaque psoriasis weighing greater than 100 kg (220 lbs):
Initial dose: 90 mg subcutaneously once initially and 4 weeks later
Maintenance dose: 90 mg subcutaneously once every 12 weeks

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

Data not available

Other Comments

Administration advice: After proper training in subcutaneous injection technique, a patient may self inject ustekinumab if a physician determines that it is appropriate. Refer to the manufacturer's product information for complete administration instructions.

Storage requirements: Keep refrigerated at 36F to 46F (2C to 8C). Protect from light. Store vials upright. Do not freeze. Do not shake.

Reconstitution/preparation techniques: Refer to the manufacturer's product information.

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