Betamethasone/Calcipotriene Topical Dosage

Usual Adult Dose for Psoriasis

betamethasone-calcipotriene topical ointment:
Psoriasis vulgaris: apply to the affected areas once daily for up to four weeks. The maximum weekly dose should not exceed 100 g.

betamethasone-calcipotriene topical suspension:
Psoriasis vulgaris of the scalp: apply to the affected areas once daily for 2 weeks or until cleared. Treatment may be continued for up to 8 weeks. The maximum weekly dose should not exceed 100 g.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Treatment of more than 30% body surface area is not recommended.

Betamethasone-calcipotriene ointment should not be applied to the face, axillae, or groin.

Safety and effectiveness in pediatric patients have not been established. Due to a higher ratio of skin surface area to body mass, pediatric patients are at greater risk of systemic adverse effects when treated with a topical medication.

Hypercalcemia has been observed with use of betamethasone-calcipotriene ointment. If elevation of serum calcium outside the normal range occurs, treatment should be discontinued until normal calcium levels are restored.

Hypothalamic-pituitary-adrenal (HPA) axis suppression has been observed with the use of betamethasone-calcipotriene ointment. Patients receiving a large dose of a potent steroid applied to a large surface area should be monitored for evidence of HPA axis suppression using the Cosyntropin Stimulation Test.

If concomitant skin infections are present or develop after treatment initiation, an appropriate antifungal or antibacterial agent should be used. If improvement is not seen, use of betamethasone-calcipotriene ointment should be discontinued until the infection is adequately controlled.

Dialysis

Data not available

See also...