Zofran ODT for Nausea/Vomiting User Reviews (Page 2)
Zofran ODT has an average rating of 7.0 out of 10 from a total of 52 reviews for the treatment of Nausea/Vomiting. 63% of reviewers reported a positive experience, while 29% reported a negative experience.
Reviews for Zofran ODT
- Dmp
- April 11, 2017
"This stuff works like a dream and quickly! I take over 20 meds a month, and sometimes I just get flat out nauseated from my "cocktail from hell". I have also had it administered in an IV, and it cant be beat. The only downfall is the cost...the last I heard it is $20 per pill, and Medicaid balks at paying for it."
- Renee
- Taken for 10 years or more
- March 9, 2022
"I have been taking Ondansetron, 4 mg ODT for years to treat severe nausea after I eat too many carbs during a meal. When I feel the nausea starting, I put 2 tablets under my tongue followed by a Chewy Tum and a Prilosec ODT. I was given Promethazine before Zofran was available to me which worked fantastic cuz it puts you to sleep and you sleep thru the nausea episode which is not practical when you are working. Zofran saved me by allowing me to recover from nausea episodes taking 30 minutes out of my day vs 1/2 or entire day off work. Great drug!!!"
Frequently asked questions
- Abby
- Taken for 1 to 2 years
- December 26, 2021
"I have been suffering with cyclic vomiting syndrome for around 5-6 years now and zofran is the only thing that works. My nausea and vomiting is so severe that I do need to take double the recommended dose, however it does work. I have never had a single side effect from Zofran. I understand this drug might not work for some people, but for me it is great!"
- Lila...
- April 27, 2017
"First time I took it I felt better almost instantly- it was truly crazy! The second time was the same but the third time it didn't help as much. However, it helped some and has so far kept me a little less feeling like I'm gonna puke. Better than nothing."
Are you taking this medicine?
- Anonymous
- April 20, 2012
"I am/was taking this medicine to combat nausea from post chemo treatments and I found that it did give me a headache and I could not stand the taste it left in my mouth when the medicine disintegrated on my tongue. "
- Gastr...
- Taken for 1 to 2 years
- May 20, 2017
"I use this when I am driving and have nausea and was under doctor's instructions to take it twice a day until I was prescribed the scolopamine patch for nausea. Now, I just take it on the times I feel nauseated with the patch, which is not much. I like the dissolvable tablets because they are quicker than the pills to absorb and I can just carry them with me in my purse, unlike the phenergan suppositories, which have to be refrigerated or kept in a cooler when going somewhere."
- Anonymous
- Taken for 6 months to 1 year
- November 30, 2021
"Zofran is a miracle drug for me. I always have some on hand. I suffer from GERD, IBS, gastritis, malabsorption, endometriosis, and the list goes on. Nausea is a nagging symptom that I have often, and I vomit on a regular basis. Zofran has kept me out of the ER on many occasions due to severe vomiting. It also gets me through the occasional rounds of antibiotics as they really mess with my stomach. It does cause some pretty bad headaches when taken on a regular basis, but I will take a headache over vomiting any day. Could not recommend enough! It has been a total lifesaver!"
- Tori
- Taken for 2 to 5 years
- March 1, 2024
"I take Zofran as part of my treatment for panic disorder that often causes nausea. This drug has never failed me. It always cures my nausea within an hour, and I've never thrown up while taking it. Only problem is it makes me constipated, and sometimes gives me a headache."
- MDDMom
- Taken for 10 years or more
- December 13, 2021
"Frequent migraines and Cervicogenic headaches often make me extremely nauseous, which subsequently may cause me to vomit, not a good occurrence with massive headaches. I’ve also had intractable vomiting, and received zofran IV or suppository (effective but unpleasant). I’ve tried other anti nausea medications to little effect. 1 dissolving tablet at the onset of pain-related nausea works extremely well for me. In over a decade of taking it (including while pregnant) I’ve had no side effects despite being on a number of medications."
- LilMi...
- Taken for 10 years or more
- February 1, 2024
"I have taken Zofran for migraines and cyclical vomiting syndrome for nearly 2 decades. The last 8 years, I have taken it daily. It worked wonders for several years; however, my health has rapidly declined from chronic illness and a couple of autoimmune disorders. Now, when I take it, I throw up in a matter of minutes. I'm wondering if I'm reacting badly because I've taken it for so long? I think I'll talk to my doctor about stopping it for a while to see if it's causing me more trouble than it's worth. Overall, it worked wonders for me for 10-15 years. I'm deducting points for taste and possible long-term side effects."
- Disso...
- Taken for less than 1 month
- November 22, 2021
"I took ondansetron swallow-pill at 4mg and it was starting to help. My physician increased the dose to 8mg but it was now a mouth dissolving-format and made my nausea FAR WORSE. Pharmacy says the can distribute 8mg in the swallow pill form, but the doctor has to prescribe it in that format."
- Stomach...
- Taken for less than 1 month
- January 8, 2022
"Took for a few days after getting food poisoning which turned into a stomach virus. It worked for a hour or two, but the nausea came back worse. No vomiting surprisingly but didn’t really help my nausea."
- Bjcg
- Taken for 1 to 6 months
- December 27, 2016
"The directions say to dissolve in the mouth but it's very bitter. Does anyone else have this problem?"
- Erynnj
- August 19, 2014
"Only thing that works! I have MSK and vertigo and BOTH cause nausea with flare ups and this is my life saver!"
- Chantel
- August 18, 2016
"This medicine did nothing except constipated me and give me a headache!"
- Googe
- July 10, 2016
"Had kidneys stone. Took pain meds for it. Got super nauseous at night. Took zofran, and within 10 minutes I was not nauseated at all. Amazing medicine."
- Wingnut
- July 29, 2019
"I have nausea and vomiting from the flu and this medication either did nothing or made me more nauseous."
- Lithh
- Taken for 2 to 5 years
- April 19, 2016
"Best nausea medication in my opinion. I use it for nausea associated with my migraine headaches and it works extremely fast and well."
- Hatchet
- Taken for less than 1 month
- August 21, 2018
"Works well with me. Stopped my nausea and vomiting right away"
- Evilm...
- Taken for 6 months to 1 year
- October 9, 2018
"This medication is amazing! The dissolving version is so convenient and I can carry 1 part of a blister pack in my wallet."
- Anonymous
- November 11, 2008
"This works very well"
- pookie...
- September 1, 2012
"After surgery long term nausea due to pain medicines"
- Anonymous
- July 12, 2010
"Medicine serves it's purpose; but gives me SEVERE headaches. Like "hangover" headaches in the morning or shortly after I take them (1 hour or so)."
- Brad...
- Taken for 2 to 5 years
- April 19, 2016
"I have a lot of GI, p"
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Nausea/Vomiting
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More about Zofran ODT (ondansetron)
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- During pregnancy
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- Drug class: 5HT3 receptor antagonists
- Breastfeeding
"I've been traveling and taking Zofran. In the past if I took Zofran once, it seemed to be okay. But after taking multiple doses, these last few days of travel, I've been having nausea, vomiting, diarrhea, muscle spasms and numbness/tingling in my limbs. When I would feel a little off, I would take Zofran not realizing that it was making things worse for me!!! I also looked up any possible drug interactions and it appears that it has a major negative interaction with Zoloft (which I take!). It's ruined the first part of my trip and I'm praying that I can start feeling better so I can enjoy the trip that I have dreamed about for decades now!"