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Nystatin User Reviews & Ratings

Brand names: Bio-Statin

Nystatin has an average rating of 4.7 out of 10 from a total of 97 reviews on Drugs.com. 30% of reviewers reported a positive experience, while 47% reported a negative experience.

Reviews for Nystatin

  • Kay...
  • June 30, 2019

For Oral Thrush "I was on antibiotics for an extended time and after 4 months, I developed thrush. After starting this medicine, I noticed my mouth became extremely dry, especially at night while sleeping. My tongue had a funny burning sensation and everything tasted odd. Has anyone else had this same problem? Also, I got really bad diarrhea and stomach cramps."

2 / 10
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218 Report
  • Regis...
  • Taken for 1 to 6 months
  • December 13, 2020

For Oral Thrush "I have used Nystatin twice in 6 months because I take an inhaled corticosteroid, which has caused thrush on tongue especially in the posterior of the tongue. A couple of things to note: be sure to swish nystatin aggressively and gargle as well to help access the very back of the tongue. Then do not eat or drink for 30 mins. Lastly, using a tongue scraper to remove loose debris and clean the tongue."

9 / 10
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133 Report
  • Chris...
  • Taken for less than 1 month
  • May 13, 2020

For Oral Thrush "Laryngitis for 6 weeks that gets worse as the day goes on to the point that by the end of the day it physically hurts to talk. But with COVID, I was scared to see a doctor. No other COVID symptoms. Finally saw a doctor, no COVID, no strep. 2 weeks later, no improvement. Tested for COVID again, negative again but this time, doctor diagnosed thrush (no idea how you get that???) and gives me nystatin 4 times a day. Day 2, voice sounds better, lump feeling in throat almost feels gone. I can talk, throat not so painful but tongue feels like I ate a bag of sour candy. When I take the nystatin, it tingles on my tongue - is this normal? Should my tongue hurt like this afterwards as well?"

6 / 10
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130 Report

Frequently asked questions

  • Maia
  • Taken for less than 1 month
  • April 26, 2019

For Oral Thrush "I had oral thrush on my tongue. The Nystatin cleared it in a few days, but since then (6 weeks ago), nothing tastes the same anymore. It's as if it's affected my taste buds and mucous membranes. My tongue feels strange, slightly scalded, and very squeaky against my teeth and the inside of my mouth. It's as if there's enough saliva, but it's not slippery enough. It's really unpleasant. I'm assuming it was the Nystatin that caused it and really hope it returns to normal soon as I don't enjoy anything I eat or drink."

5 / 10
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148 Report
  • Kim
  • November 20, 2019

For Oral Thrush "I've had oral thrush for approximately 3 months. I got it from being extremely stressed and anxious. (Yes, I never knew you could get it that way either.) I was on Diflucan for 7 weeks, and it didn't touch it. I'm beyond frustrated with this. Today, I quit the Diflucan and went to nystatin 5 times a day. Please pray this goes away from me."

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124 Report

Are you taking this medicine?

  • Jimpe...
  • July 26, 2019

For Oral Thrush "Prescribed Nystatin for oral thrush after 10 days on Amoxicillin. My throat was red and raw, my tongue hurts, sores on back/sides of tongue. Nystatin made a huge difference within just a couple of days. It has slowly improved each day as I have taken it 4x/day. I’m on day 7 today, and I would say it’s almost gone... still getting some discomfort on the tongue on and off - taking Advil for that. I’m confident it’ll be all gone by day 10 of the medication. I’m extremely hopeful."

9 / 10
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120 Report
  • Shay
  • February 3, 2021

For Oral Thrush "This is my second round with nystatin, which came back about a month after having thrush for 3 months because I was put on antibiotics for a staph infection. I combine the nystatin with holistic measures, #1 being diet. No carbs, sugar, or alcohol, as candida thrives on sugar, and carbs and alcohol break down into sugar in the body. The last thing you want to do is feed the candida fungus. The first round didn't work at all, and I suspected it actually made it worse. This time I caught it early and started right away on the diet, Candida-Killer tea, baking soda swishes, and hydrogen peroxide swishes. I didn't start with the nystatin until a few days in. I noticed after 24 hours that it had gotten worse, so I researched the ingredients. First ingredient: alcohol! It also contains sugar! Nystatin also contains saccharin, which upsets the flora system... again, the last thing we need. In a nutshell, nobody should take this medication as it is counterproductive."

1 / 10
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81 Report
  • Jin...
  • Taken for less than 1 month
  • July 5, 2019

For Oral Thrush "I am using Nystatin Oral 4 times a day for 7 days. Been on many rounds of antibiotics for recurrent UTI infections and such... So, the end result is thrush. So, Nystatin is not working for me at all. I have been on 3 bottles of it already, and it's made very little difference. I switched to a natural apple cider vinegar remedy, and it seems to clear it way faster than the Nystatin."

3 / 10
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97 Report
  • brain...
  • July 11, 2009

For Oral Thrush "My father, a brain tumor patient, had oral thrush, which is very common for those taking long-term Dilantin. This swish-and-swallow medication worked wonders for him, within about 3 days. Be sure to take it for the full prescription period, usually 14 days. Also, the longer you can hold the gargle, the longer the contact between drug and organisms. Thrush can also move from the mouth into the throat, and it can recur quickly, so out of sight doesn't necessarily mean anything. Again, take it for the full period recommended by the doctor."

10 / 10
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202 Report
  • Ash
  • April 2, 2020

For Oral Thrush "I developed oral thrush for the first time after taking Macrobid (generic for UTI). The antibiotic made me outrageously ill from all of the extreme side effects I experienced. I was able to get nystatin over the phone. However, I immediately had a severe reaction of chest tightness and a rapid and abnormal heart rate. Luckily, about 24 hours later, it seems to have subsided, but now I’ve been trying everything I can OTC. Nothing is giving me relief. The feeling in my throat is horrible, and sometimes it’s unbearable and impossible to swallow. I’m definitely dehydrated as I cannot even force myself to sip, let alone drink water. Doctors have been less than helpful as they don’t want to see patients due to social distancing guidelines from COVID. I’m hoping the use of baking soda and saline mouthwashes, as well as acidophilus probiotic pills, will start being effective, as I can’t take much more of all of these issues. (Within 15 mins, the nystatin reaction set in)"

1 / 10
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67 Report
  • JanieK
  • October 11, 2019

For Oral Thrush "I was on Nystatin for about 10 days. Unfortunately, no one, including Walgreens, caught the fact that it is contraindicated when one is taking Warfarin blood thinner, i.e., there is a drug interaction between Nystatin and Warfarin. Had a GI bleed. Almost did not survive this screw-up. Look up every medication prescribed, and if you have questions or weird symptoms, ask for extra info before ingesting. We have wonderful medical technology, but screw-ups are rampant."

1 / 10
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67 Report
  • Amanda
  • Taken for less than 1 month
  • May 4, 2020

For Oral Thrush "I actually developed oral thrush from something really bizarre. So because I had to work during this coronavirus crisis, every time I came in, I was so paranoid about something being in my mouth, like virus particles that I was rinsing with an extremely heavy alcohol mouthwash. I developed thrush because of this. I have been taking this medication for about 2 days. So far, it has not helped. I noticed that somebody else wrote something which is actually happening to me also, which makes me a little nervous. I have been having some kind of weird twinges in my chest. I am really paranoid that the infection has spread down my esophagus and into my lungs. This is a possible complication of thrush. I will give it another 2 or 3 days, and then I will go back to the doctor. The only problem is I'm really scared because I have to go to urgent care, and with everything that is going on, I am so paranoid about going to urgent care."

3 / 10
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59 Report
  • Joe
  • Taken for 1 to 6 months
  • June 5, 2020

For Oral Thrush "Nystatin is absolute garbage. I’m now on my 4th bottle with no sign of it doing anything. I’ve also pumped myself with probiotics and limited alcohol. Very frustrating, and Nystatin seems to do nothing. Tastes good at least, but not effective. Based on so many other negative reviews, it’s surprising how popular this is prescribed to adults with oral thrush."

1 / 10
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51 Report
  • Dwain
  • Taken for less than 1 month
  • November 27, 2019

For Oral Thrush "Well, I didn't use nystatin, I use essential oils, not a fanatic user of, but knowing tea tree oil is a fungi killer. So salt water, tea tree oil with a splash of mint spray, and water is working great. Just trying to stay off the sugar and yeast, the Candida diet is hard, but the essential oils are working. Was prescribed prednisone and antibiotics for 5+ days after 4 days in the hospital with double pneumonia."

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  • Awano
  • Taken for less than 1 month
  • September 13, 2020

For Oral Thrush "On 2nd bottle of Nystatin for oral thrush at back of tongue, it seemed to work initially, but symptoms are getting worse now. I'm struggling with bad breath, metallic taste, sore tongue, and loss of appetite. I guess I have to go back to the GP."

1 / 10
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46 Report
  • Verym...
  • Taken for less than 1 month
  • July 25, 2017

For Oral Thrush "Maan, is this medicine a gift from GOD!!! It works wonders and I am only on day 3. I've been suffering with unknown candida for 4 years, with it now affecting my stomach, throat, and tongue. The coughing has subsided, and my tongue is amazingly clear! I thought I was an alien of some sort, dealing with a weird-looking tongue all of these years, but thanks to my doctor's diagnosis and prescribing nystatin, I feel so much better. I suffer from systemic lupus, and all of my medicines are causing the thrush. Amazing product, and it doesn't taste half bad either. My only gripe is that nothing tastes the same anymore, but maybe that's temporary."

10 / 10
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67 Report
  • Waf
  • Taken for less than 1 month
  • November 8, 2019

For Oral Thrush "I'm currently having chemo, and with my low WCC, developed a lovely case of oral thrush. It was really sore to swallow, and the back of my throat was pretty coated. Been taking nystatin for 2 days and have already noted a great improvement, so thumbs up from me. It doesn't taste too bad either."

8 / 10
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42 Report
  • Kano
  • Taken for less than 1 month
  • October 26, 2020

For Oral Thrush "I've not had oral thrush before. I am a smoker, though not real heavy. I also have dentures that don't fit correctly. So, Dr. put me on nystatin because the back/side of my tongue hurt on both sides. I finally looked at it in the mirror and saw white spots. It started spreading on the back of my throat and tongue. I took one dose 4 times a day faithfully. It started clearing up after about my 5th day of taking the medication. So everything was fine until 3 days after my medication ran out. It's now back and starting the same way as last time, with my tongue hurting on both sides. The doctor is going to do another treatment, the same as the last one. If it doesn't stay away, they want to send me to an ear, nose, and throat doctor and have a biopsy done. Now I'm really freaked out and anxious. I didn't get any side effects from this medication and feel it worked well, but I don't understand why it came back."

8 / 10
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35 Report
  • Illin...
  • Taken for less than 1 month
  • July 30, 2014

For Oral Thrush "63 yrs old, was prescribed liquid nystatin 100,000 units/ml, 2 tsp. four times a day as needed for thrush that was in my throat, and I believe going into my esophagus. It was not in my mouth this time (I had it 6 years ago). I read where hydrogen peroxide kills it and had been using toothpaste with hydrogen peroxide in it, so it wasn't on my tongue. But my throat hurt, and I was actually coughing up blood in my sputum. After only two doses, my throat and chest don't hurt, coughing has lessened, and I believe the bleeding has stopped! I noticed the dose is for kids, but I'm 63. However, it is working! I could hardly swallow, it hurt so much. Not hurting after only 2 doses. Amazing medicine! I was given a 3-day supply."

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  • Meme
  • May 24, 2018

For Oral Thrush "I was diagnosed with oral thrush after first being told the sores on the corners of my mouth were caused by drooling in my sleep. It was a year or so after I rinsed my mouth out with mouthwash that my tongue developed sores and became so painful and my throat tried to close that I saw my doctor. She diagnosed oral thrush and gave me Nystatin. This is the second day, and already the knot is gone from my throat. This is truly a wonder drug for this horrible condition. I smoke, take other meds, and wear dentures, which makes me a candidate for the thrush. If it comes back after I get it healed, I will get more Nystatin."

10 / 10
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44 Report
  • Dale
  • Taken for 1 to 6 months
  • September 6, 2020

For Oral Thrush "Just finished my 2nd bottle of nystatin for oral thrush. Ever since then, I wake up with severe dry mouth. My heart even skips a lot now. This dry mouth is so bad, when I sleep, it is horrible. Now, not sure if the oral thrush is even gone. Now on my 3rd 14-day treatment with this junk... Seems to get rid of thrush for only a week or so. May have to do pill next. Pill can cause heart issues though, so trying to avoid it."

1 / 10
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30 Report
  • Suz
  • Taken for less than 1 month
  • April 8, 2021

For Oral Thrush "This medicine is awful. Took 5ml and it burned and made my cheeks swell and mouth burn. Told my Dr. He said just try out a little more so I only used .5ml. My tongue hurts so bad. Feels like I've been chemically burned. Called pharmacist. He said stop taking it immediately. This stuff isn't good for me."

1 / 10
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25 Report
  • Kiki
  • Taken for less than 1 month
  • April 21, 2020

For Oral Thrush "I’ve been on Nystatin for 7 days after being diagnosed with dry mouth. I have not seen any improvement for oral thrush. I am going back to the Dr to ask for a stronger medication for this damn white tongue."

1 / 10
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29 Report
  • Cjano
  • Taken for less than 1 month
  • November 4, 2019

For Oral Thrush "Taking Nystatin for thrush that was caused by Protonix. Sadly, this is giving me chest pain and causing my heart to race for 1.5-2 hours after taking it and only intensifies every time I take it. The pharmacist recommended that I stop taking it and call my doctor. I hope something else can clear the oral thrush."

1 / 10
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31 Report
  • Invad...
  • Taken for less than 1 month
  • June 15, 2021

For Oral Thrush "So far I’ve been on Nystatin “mouthwash” for 4 days and it’s been miserable. My mouth is so dry it’s uncomfortable and my tongue feels raw and dry. Nothing is helping so I’m beginning to wonder if this side effect isn’t from overusing. My thrush cleared in 2 days with this, so by all means it’s amazing for oral thrush, but I’m beginning to wonder if it’s not just burning my tongue since there’s no longer thrush in my mouth to fight?? That rubber banana flavor is quite literally vomit worthy, my tummy has been making LOUD noises and like others, I’ve had a few strange heart palpitations(?) after taking it..but it DID work (4ml 4x daily) to clear the icky. I cannot wait to be done with it."

10 / 10
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22 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.