Estradiol User Reviews & Ratings (Page 5)

Brand names: Estrace, Estradiol Patch, Dotti, Estrogel, Vivelle-Dot, Climara, Minivelle, Divigel, Femring, Estraderm, Delestrogen, Lyllana, Alora, Depo-Estradiol Evamist Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 5.7 out of 10 from a total of 548 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Estradiol

jessn...
Taken for 1 to 6 months
November 5, 2018

For Gender Dysphoria "Estrogen It's the bestrogen Makes grow of breastrogen But seriously, I can't recommend estradiol enough. I've been taking it sublingually for around 4 months now (2mg daily for the first 3 months, increased to 4mg last month) and I feel like an entirely different person. My skin feels so much softer (even though it's still just as dry >:( ), and I've noticed a fair bit of breast growth (they look a bit bigger but feel much different due to an increased amount of tissue), as well as more fat on my face. The one downside is the mood effects; my emotional lows are pretty low. Luckily my highs are much higher than they ever were before. I'd recommend any trans woman get on estradiol ASAP (provided they're not on it already haha)"

10 / 10

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34 Report

lklein
September 5, 2008

Vivelle-Dot (estradiol) for Postmenopausal Symptoms "I started using the Vivelle-Dot patch after having a total hysterectomy. Before starting the patch, I was having vaginal burning & itching, hot flashes, and night sweats. Within a week of starting the patch, all of these symptoms were resolved. To date, I've not experienced any side effects."

10 / 10

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74 Report

Super...
Taken for 1 to 2 years
April 5, 2018

Vivelle-Dot (estradiol) for Postmenopausal Symptoms "I have more energy and have noticed that I care about my physical appearance, I am sleeping better and can find words again on the brand name vivelle dot. The pharmacy tried to give me the generic but that doesn’t seem as effective. It’s way too expensive but am paying the price for a better quality of life."

8 / 10

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36 Report

spunky...
September 11, 2015

For Postmenopausal Symptoms "In short, upon having my name brand hormone patch replaced by this awful generic, I basically had my estrogen level drop to almost nothing in less than four months. The patch didn't stick, it kept coming off, I started experiencing all post menopausal symptoms to the extreme. I didn't know what was going on at first.This generic will not do the job. I can't believe the FDA approved this generic medication! It has been the worse 6 months of my life! Since going back on the named brand, after just one month, my estrogen level is increasing and all menopausal symptoms are starting to go away. To anyone considering the money saving is cashing in their own sanity, it's not worth it! I'd give it 0, but that's not an option."

1 / 10

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47 Report

South...
Taken for 5 to 10 years
January 26, 2019

Vivelle-Dot (estradiol) for Postmenopausal Symptoms "I started the patch in 2011. Six months later I started experiencing pain from my back down to my toes. (It didn't even cross my mind it would be the patch) I went to so many doctors & had lots of test, tried a ton of medication. I've been misdiagnosed so many times. Late 2018 it's like a lightbulb went off I started ready reviews on this patch. I decided to try the hormone pellets to see if in fact Vivelle was the problem. It's been 6 months since I started the pellets & thank goodness I'm slowly getting better!!!! The pellets are expensive but at this point I have wasted 7 years of extreme pain. PLEASE STAY AWAY FROM HORMONE PATCHES!!!!!"

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32 Report

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JSano
June 18, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I have used the Alvogen product successfully for several years. When my pharmacy said it was no longer available and substituted the Mylan patch I was, frankly, shocked. What a piece of junk. It is huge, does not adhere and, compared to the generic Climara product produced by Alvogen, it is like stepping into the dark ages. I am paying extra to now use the brand name rather then generic. It appears from looking online that it is the same clear, low profile product. I agree with other reviewers who also feel strongly about this issue. I phoned Alvogen and it apologized about no longer carrying it. It is little comfort."

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30 Report

Rosel...
Taken for 1 to 6 months
January 7, 2016

Estradiol Patch (estradiol) for Oophorectomy "After using Vivelle patch for a number of years following a complete hysterectomy, my insurance company refused to pay for it at the same level due to the Mylan generic. Within a few weeks of switching to the generic, I began to develop adverse symptoms (insomnia, breathing difficulties, anxiety, constant headache). When I made the connection and switched back to Vivelle, the symptoms subsided. Unfortunately, my insurance company refuses to pay for the brand name at the same level, but this is not the same drug. Now instead of paying $40 for a 3-month supply, my cost is over $150 to obtain the brand name product."

1 / 10

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45 Report

BABS
Taken for 10 years or more
July 19, 2022

For Postmenopausal Symptoms "Ladies, I am 73-years old and have been on Birth Control pills from 18-years old to 53-years old ... I opted for a career over a family since I didn't want to be subservient to a man or financially dependent. After menopause, my OB-GYN doctor prescribed a combination of Estradiol-Norethinorone 0.5/0.1 (the lowest pill dosage possible). And I remember him saying to be careful which country you get it from because they're not all good. So I have been on estrogen replacement now for 20-years with no side effects of any kind. I moved and my new doctor and she wants to take me off of estrogen replacement and put me on an anti-depressant. Why take me off of a drug and then see what my side effects will be before putting me on another drug? Why change something that I've been happy with for YEARS with no problems or health issues. I get my yearly pap and manno tests and my health is good (no high blood pressure or cholesterol). Need I say more? I'm finding another OB-GYN that understands me."

10 / 10

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14 Report

Mar
Taken for 1 to 6 months
November 1, 2019

Dotti (estradiol) for Postmenopausal Symptoms "This Dotti patch doesn’t work! Provided no relief. Went from a stable estrogen level on another brand to 43 by the time I quit it. It doesn’t work. Went back to other brand and instantly got relief from hot flashes and mood instability."

1 / 10

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28 Report

AZNurse
Taken for 1 to 6 months
September 24, 2022

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I was prescribed the mylar estradiol patches 0.5mg twice weekly. I've had no issues with adherence, except 1 patch and that was user error. It definitely improved my symptoms of night sweats and vaginal dryness. I'm also taking 200mg of progesterone to combat insomnia. I had an ovary sparing total hysterectomy in January this year and noticed an increase in symptoms. Labs show ovaries still working, but levels up and down consistent with perimenopause at 45 years old. Don't suffer needlessly, there's help!"

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13 Report

Ramona
Taken for 5 to 10 years
February 18, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I read through many of the comments - and I could NOT agree more about the Mylan patches. I stopped using them years ago for the same reason: too big, skin reaction, and they just didn't adhere to the skin. I had received such a poor quality supply, I wrote directly to the manufacture. They did send me a refund check for two of the three months I requested. AT this point I found Alvogen brand. This has been the best estrogen patch ever- however, I just went to refill at WalMart and they said that Alvogen was no longer available for shipment to them. Was told it was discontinued being sent to WalMart. CVS did have some of what I needed on the shelf for now. I am doing some research to find out what is happening."

1 / 10

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31 Report

KPano
Taken for less than 1 month
July 22, 2021

Dotti (estradiol) for Postmenopausal Symptoms "I was so relieved to find these reviews. My doctor uses another pharmacy for "ease" and as a result I got the Dotti Estradiol patch. I used it for four days. It does not work. I got hot flashes, red patches, mood swings -- the works. It felt like life was so bleak. Less than 10 hours back on Sandoz and things are looking up again. Red patches gone. No hot flashes... Why do they even make this patch?!"

1 / 10

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19 Report

april...
Taken for 2 to 5 years
April 18, 2015

For Postmenopausal Symptoms "Been using estradiol patches for the past 2 years since my full hysterectomy. I am 39 years old. No side effects. Can't live without them. One day with no patch and hot flashes, fatigue and moodiness is back."

10 / 10

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46 Report

Delila...
Taken for 2 to 5 years
August 31, 2015

For Gender Dysphoria "so i started transitioning at 18 and after a lot of research i settled on premarin as its the closest to organic estrogen. after 2 years on that i gained too much weight for myself to continue without risking blood clots or a stroke. mydoctor said "yyou're switching to estradiol" i was like ok. after maybe 3 weeks when my sex drive came back and my weight went wayy down i knew i had made a grave mistake years ago. this may be synthetic but its most customly fit for humans. then i started developing again. this med has changed my life for the better"

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44 Report

Cathy...
April 21, 2023

Estradiol Patch (estradiol) for Postmenopausal Symptoms "The Estradiol patch has made a functional life possible for me. Please review the latest NAMS 2022 Position Statement for updated side effects. This presents a clearer and more accurate summation of increases benefits and less or null risks for the use of Estradiol transdermal patch. I will continue to use the patch as an early user and now in my 70s under close supervision of my PCP."

9 / 10

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9 Report

Anonymous
December 24, 2010

Climara (estradiol) for Postmenopausal Symptoms "I have used 0.75 patch for 6 years. To make it stick better, rub your skin with alcohol and let dry. Press on for ~20-30 secs. Really the only thing I find frustrating is the fact that by the 5th day my body is clearly not getting as much medicine, and I start having body symptoms to parallel this. Also have very sore knots in my breasts, especially the first few days. But other than this, it has been a life-saver since I have post surgical menopause."

8 / 10

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61 Report

Anonymous
Taken for 6 months to 1 year
September 22, 2020

Estradiol Patch (estradiol) for Postmenopausal Symptoms "The Estradiol Patch causes redness, severe itching and burning. I have marks that are taking months to heal. I have had other brands that do not cause this reaction. I am having a hard time getting a brand other than Mylan from my pharmacy."

1 / 10

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23 Report

Well...
Taken for less than 1 month
June 28, 2012

Vivelle-Dot (estradiol) for Primary Ovarian Failure "I am in my early forties and menopause hit me at an early age. I struggled with whether or not I should go on HRT due to the risks. With that said, the symptoms were creating shear havoc in my life (severe hot flashes, night sweats, insomnia and decreased libido-my poor husband). I am happy to say that after my first application, I slept through the night for the first time in two years! My hot flashes have decreased and I don't have that foggy feeling in my head. I am on Vivelle dot and a progesterone regimen. (light doses). I began Vivelle dot two weeks ago and would highly recommend it."

10 / 10

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55 Report

Ketty
Taken for 1 to 6 months
November 11, 2020

Divigel (estradiol) for Postmenopausal Symptoms "I have been taking Divigel .5 for 6 weeks and 100 mg progesterone pill and my mind has cleared magically. However, I have gained 3 lbs and my breast got bigger as well as my stomach. It is very upsetting because I have been 127 lbs all my life. Some one has experience the same?"

8 / 10

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22 Report

Queen...
Taken for less than 1 month
December 29, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "My complaint is against SANDOZ brand of estradiol patch specifically - they do not work for me for some reason. I've been on Alvogen for a long time and everything was great and it worked well. Pharmacy gave me Sandoz brand and I started menopause symptoms in 2 weeks. The next time I picked up my prescription they had Alvogen brand again and about a week after taking it - I started feeling better again. Then they said they didn't have Alvogen again so I tried Sandoz again and again - within two weeks, I am feeling my menopause symptoms. For those of you having problems with the patches falling off - I put the patch on my Butt/Hip area beneath my underwear. The underwear helps to keep it on."

1 / 10

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26 Report

Annie
August 21, 2020

Dotti (estradiol) for Postmenopausal Symptoms "This patch was forced on me by my pharmacy saying it worked the same as my other brand patches but was not true. After a week of using them started having horrible hot flashes and could not sleep. A waste of money. I went back to my regular ones and lost the money I paid for the Dotti."

1 / 10

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23 Report

Just...
Taken for 1 to 6 months
December 4, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I have used Estradiol patch for one month. I was hesitant given the reviews that the patch falls off. Mine sticks on great. I exercise, shower, bathe, with no issues. My symptoms have greatly improved. I use the Mylan generic."

10 / 10

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26 Report

Anony...
Taken for less than 1 month
August 11, 2013

Minivelle (estradiol) for Postmenopausal Symptoms "It has been 5 days into my dose of Minivelle. My hot flashes reduced drastically, however, the very next day I developed severe arthritis in my knees. It took me until today to realize this could be a side effect. After reading- it is. I have discontinued the patch and hopefully my knees will get better."

4 / 10

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50 Report

Mauta
Taken for 1 to 2 years
July 23, 2015

Minivelle (estradiol) for Postmenopausal Symptoms "It took about 5 weeks to start working completely. My gynecologist told me to not give up. After 3 weeks I was still getting hot flashes daily. I continued as prescribed and Zero hot flashes!! No side effects. One year using"

10 / 10

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43 Report

Anonymous
November 8, 2017

Climara (estradiol) for Oophorectomy "At the age of 43 I had a complete hysterectomy due to out of control endometriosis. One week after surgery my doctor prescribed Climara and almost 21 years later I'm still using it. I never have hot flashes or any other symptoms of menopause. The patches have occasionally come off but that's my own fault if I don't make sure to get it firmly attached. If you rub it on there really well it'll stay put all week. I don't ever plan to stop using them. I also skip using my insurance and order them from a Canadian Pharmacy and pay out of pocket. Cost with insurance in the US=$400 per month. Cost from Canada=$40 per month. It's the exact same thing, manufactured by Bayer."

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34 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.