Pregnancy Warnings

Estradiol Pregnancy and Breast Feeding Warnings

Estradiol is also known as: Adgyn Estro, Aerodiol, Alora, Bedol, Climara, Climaval, Climodien, Clinagen LA 40, Delestrogen, Delidose, Dep Gynogen, Depo-Estradiol, Depogen, Dermestril, Dermestril - Septem, Dermestril Septem, Dioval 40, Dioval XX, Divigel, Dura-Estrin, Duragen, Elestrin, Elleste Solo, Esclim, Estra-C, Estra-V 40, Estrace, Estraderm, Estradiol G GAM, Estradiol Patch, Estradot, Estradot 100, Estradot 37.5, Estradot 50, Estradot 75, Estragyn LA 5, Estrapatch, Estrasorb, Estreva, Estring, Estro-Cyp, Estro-LA, Estro-Span 40, Estrofem, Estrogel, Estrogen Patches, Evamist, Evorel, Fematrix, Fempatch, Femring, Femsept, FemSeven, FemSeven Sequi Phase I, FemTab, Femtrace, Femtran, Gynodiol, Gynogen LA 20, Medidiol 10, Menaval-20, Menorest, Menorest Patch, Menostar, Nuvelle TS Phase I, Oesclim, Oestradiol, Oestradiol Implants, Oestrodose, Oestrogel, Oestrogel Pump-Pack, Organon Oestradiol, Oromone, Primogyn Depot, Progynova, Progynova TS, Provames, Sandrena, Systen, Thais, Thaissept, Valergen, Vivelle, Vivelle-Dot, Zumenon

Overview

Do not use Estradiol Gel Packets if you are pregnant. If you think you may be pregnant, contact your doctor right away. Estradiol Gel Packets is found in breast milk. If you are or will be breast-feeding while you use Estradiol Gel Packets, check with your doctor. Discuss any possible risks to your baby.

Estradiol Pregnancy Warnings

Estradiol has been assigned to pregnancy category X by the FDA. There are no controlled data in human pregnancy. Estradiol is contraindicated during pregnancy.

Estrogenic agents have been associated with urogenital abnormalities in offspring that manifest later in life. Vaginal adenosis, squamous cell dysplasia of the uterine cervix and vaginal cancer have developed later in life in female offspring. In male offspring, the risks of urogenital abnormalities and testicular cancer later in life are increased.

Estradiol Lactation Warnings

Limited data are available on the excretion of estradiol into human milk. The American Academy of Pediatrics considers estradiol to be usually compatible with breast-feeding despite reports of "withdrawal" and "vaginal bleeding". Estradiol has been shown to decrease to quantity and quality of the milk. Estrogens are not indicated for the prevention of postpartum breast engorgement. The manufacturer recommends that caution be used when administering estradiol to nursing women.

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