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Estradiol User Reviews & Ratings (Page 4)

Brand names: Estrace, Estradiol Patch, Dotti, Estrogel, Vivelle-Dot, Climara, Minivelle, Divigel, Femring, Estraderm, Delestrogen, Lyllana, Alora, Depo-Estradiol Evamist Elestrin Menostar Estra Pellets …show all brand names

Estradiol has an average rating of 5.7 out of 10 from a total of 548 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Estradiol

  • lrond...
  • Taken for less than 1 month
  • February 4, 2024

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I am in perimenopause and started having horrible hot flashes 4 months ago. 10 a day at least. Crazy fluctuations between hot flashes and cold chills and shivering. Night sweats at night. Was miserable. Finally found a GYN who is current with the research and she prescribed the patch and progesterone pills. She initially prescribed a brand name 2x a week 0.05 patch. Well the manufacturers are all discontinuing making the brand name patch because the patent is up and insurance will only pay for generic. Furthermore, there is a patch shortage nationwide, so there was only one generic available - Mylan. I Googled and read not so pleasant things and was super freaked out but had no other options, so I tried it. After one week, I noticed I had fewer hot flashes. After 2 weeks, I had ZERO hot flashes. OMG, what a relief. It’s wonderful not to have crazy temperature changes all day and night. Yes, it irritates my skin, but the patch has a lot fewer risks than pills, so it's okay."

9 / 10
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4 Report
  • primad
  • October 2, 2008

Evamist (estradiol) for Postmenopausal Symptoms "I haven't seen much mentioned about the personality change (i.e. edginess and sometimes just plain meaness) that occurs with perimenopause. I have found that using this spray it takes that edginess away. My family can tell when I forget to spray it in the morning. I don't like being mean, my nature is typically laid back and normally a nice person. It has been a big help to me and my family by giving the nice Mom back to the family."

10 / 10
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89 Report
  • Anonymous
  • March 21, 2012

Evamist (estradiol) for Postmenopausal Symptoms "I was through menopause by age 46. The hot flashes were so frequent they disrupted my quality of life. I urge you to discuss with your doctor but if you are concerned about the side effects of HRT, this is a very low dose spray. As my physician pointed out, even with one spray a day I still have less estrogen than most women my age. What do I notice? Almost no hot flashes. More energy, improved mood, fuller hair (unexpected benefit), less vaginal dryness, better sleep (use with progesterone). If you are suffering with postmenopausal symptoms and are worried about HRT, this may be a good cautious step and all you really need to stop suffering!"

10 / 10
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73 Report
  • Ali
  • Taken for 1 to 6 months
  • October 9, 2020

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I have been on Vivelle Dot for 8 years. Love it and no issues at all. I cannot find it anymore and have checked several pharmacies. I had to switch to Mylan generic. Absolutely awful. It does not stick well and comes off. It leaves red marks on my skin and is itchy. I do not feel I am getting the same amount of hormones and my body can tell the difference. I have used it for 2 months. The patch is supposed to last 3 1/2 days and I am sometimes changing after 2 days. Not happy with this. I hope to find Vivelle again. I am looking for other options."

3 / 10
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29 Report
  • Annoyed
  • June 2, 2020

Estradiol Patch (estradiol) for Oophorectomy "I had a hysterectomy/bilateral oophorectomy in February 2019. Immediately after surgery I had hot flashes and high blood pressure. I was put on Climara and everything was better. My employer changed insurance providers 1/2020 and they no longer covered Climara. They substituted Sandoz. I started Sandoz in March 2020 after Climara ran out. I noticed right away that the Sandoz patches do not stick. After being on them a few weeks, I’ve had a 20lb weight gain, pitting edema in my legs, hot flashes, and headaches. Went to my Dr and all bloodwork was normal. Thyroid function is ok. The problem is the Sandoz patches. They are faulty. They curl even under hydrocolloid dressings. The inconsistent hormone level is wrecking havoc on my body. I filed a complaint with Sandoz. I now have to pay $150 for climara instead of the $25 for Sandoz. If Sandoz isn’t working for you, file a grievance with the company. They are putting out an inferior product. I’m also filing a complaint with the FDA."

1 / 10
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31 Report

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  • Unhappy
  • Taken for less than 1 month
  • September 9, 2020

Estraderm (estradiol) for Postmenopausal Symptoms "This patch is not the same as their competitor. They ran out of my usual brand. So I have been on Estroderm for 2 weeks, I am bleeding, my anxiety is through the roof. I am exhausted. All the symptoms I had before starting the Oestrogen patch . So who knows what is in this patch ."

1 / 10
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29 Report
  • dawnc...
  • Taken for 1 to 6 months
  • August 15, 2012

Divigel (estradiol) for Postmenopausal Symptoms "After a surgically induced menopause, the onset on hot flashes and night sweats was so fierce asked my nurse practitioner what works. She mentioned Divigel. I started on the lowest dose and actually felt like myself again within one week of use. Keeping in mind you want to stay on the lowest dose possible, she reminded me that this is to cut down only on the severity of those hot flashes, not get rid of them entirely. I am so happy on this HRT. Just apply to your upper thigh once daily and that's it!"

10 / 10
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69 Report
  • RCano
  • October 18, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "I was so upset when insurance bumped my price on Minivelle and forced me to go to this generic patch. It’s terrible. Leaves an awful rash, itches and doesn’t stick. I think it should be illegal to sell these as a comparable product!!! Bring back Minivelle please!! It works perfect!"

1 / 10
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34 Report
  • kdano
  • May 2, 2021

Dotti (estradiol) for Postmenopausal Symptoms "I switched pharmacy and was given the Dotti patch rather than the Sandoz patch like I had before. Immediately my energy level dropped, chills, headache and drenching night sweats. This is not for me!"

1 / 10
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25 Report
  • KDS
  • October 8, 2020

Estradiol Patch (estradiol) for Oophorectomy "After my hysterectomy, I was having post-menopausal symptoms. My gynecologist mentioned options and I chose the transdermal patch. Initially, I used Climara because the generics were not on the market. Climara was great. Eventually, I was switched to Sandoz-manufactured patch which also worked great. This year, my prescription was filled with the Mylan-manufactured patch and those patches just fall off. It is ridiculous -- a HUGE waste of money plus all of the symptoms returned. So, I asked my pharmacy if they could get the Sandoz brand but it was on backorder until I believe this month (Nov. 2020). They recommended I check with other pharmacy chains so I did. I eventually found a pharmacy with Sandoz patches in stock. Each pharmacy that did not have the Sandoz brand told me it was on backorder. So I was lucky to find a pharmacy that had the Sandoz brand available. As soon as I started wearing their patch again, my symptoms vanished. I do intend to report the Mylan brand to the FDA."

10 / 10
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28 Report
  • Cyndi
  • Taken for 2 to 5 years
  • June 13, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "For three years I used the small clear Alvogen estradiol patch with no problems. I am no longer been able to get them because I understand they stopped making them. I am now using the Mylan estrogen patch and it is horrible. It's big, ugly, it stinks and it will not stay on. I will have to figure out something else to use because this is intolerable."

2 / 10
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35 Report
  • Anony...
  • Taken for 2 to 5 years
  • October 27, 2021

Femring (estradiol) for Postmenopausal Symptoms "Femring 0.1 is the only thing that has really worked for all my symptoms, especially moodiness, depression. After trying everything else, I was so pleased to find it. However, it definitely doesn't last for 90 days. I've notice the past year it has lasted 8 or 9 weeks at most. This round it lasted 6 weeks and I immediately know when it's not working. I literally feel terrible over night - hot flashes, irritable, depressed, food cravings. I'm desperate to somehow stock pile it! I wish the company making it could address this. But like so many women's health issues, it's not that important to anyone but us."

10 / 10
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21 Report
  • quiet...
  • Taken for 2 to 5 years
  • November 29, 2014

For Gender Dysphoria "After spending over two decades without any treatment, I sought help for my transsexualism; my doctor first prescribed spironolactone, followed by estradiol. It took a bit of time to find the proper dose to balance my estrogen levels, but patience paid off--no negatives! With estradiol, I've finally been able to start building a life for myself!"

10 / 10
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56 Report
  • Alli
  • Taken for 1 to 6 months
  • October 9, 2019

Estradiol Patch (estradiol) for Hypoestrogenism "The generic Mylan estradiol 7 day patch is useless. It does not stick for more than two days, it itches, makes my skin red, and makes me feel unwell. I agree with the poor experiences previously reported by others. I called Mylan to file a formal complaint, and suggest that you do too. Maybe they will get the message."

1 / 10
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32 Report
  • Anony...
  • Taken for 10 years or more
  • April 30, 2021

Climara (estradiol) for Postmenopausal Symptoms "Had a complete hysterectomy at 40 years old and have been on the patch for 23 years. It has been a lifesaver. Docs have tried to wean me off of it and menopause symptoms came back within 2 days. Sweating, mood swings/irritability, can't sleep, overall misery. Being on the patch, I feel close to normal and have good skin for 63 years old. I went off the patch for a week and had to get back on as quality of life was horrible without it. I felt best on .5 and was on it for 20 yrs but Doc reduced the dosage to .375 and wants me to be off them permanently because they claim it's risky for cardiovascular health (even though it's supposed to be good for bone health)."

9 / 10
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23 Report
  • Noopt...
  • August 16, 2015

Estradot 50 (estradiol) for Postmenopausal Symptoms "I have tried all the sequi and Conti HRT tablets and the best was Femoston Conti which I was on for a year before it started giving me bad side effects such as painful breasts and mood swings. Now on Estradot 50 patch with Utrogestan capsules 200 per day for 2 weeks of cycle. Feel fantastic and know I will be on these for a long time. I am 54."

10 / 10
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51 Report
  • Terrea
  • Taken for 5 to 10 years
  • February 27, 2022

Vivelle-Dot (estradiol) for Postmenopausal Symptoms "I am 65 yo. I have no uterus but both ovaries. Menopause began around 55. Severe mood swings, disabling hot flashes all day and night, unable to sleep, severe brain fog (I couldn't put two sentences together), dry skin. I was miserable. My poor husband. I went to 6 female doctors ( I figured a male Doc would be clueless), always asking the front desk if the Dr treated menopause...they usually have no idea and just say yes. I actually had one Ob/Gyn tell me she doesn't do menopause she just delivers babies. Finally with some luck and persistence I found one. I began vivelle dot estradiol transdermal patch system 2 times a week. .025, no effect. .050 no effect. .075....boom. Within 3 days no hot flashes, within a week no mood swings & fog cleared. Dry skin gone. Went on Medicare. Medicare wouldn't cover it. I appealed. My doctor appealed. I went back to miserable for 4 months. They wanted me to pay $580 for 3 months supply. Generic off brand labels want me to pay $68 per month."

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18 Report
  • del
  • February 13, 2021

Climara (estradiol) for Postmenopausal Symptoms "I have used the Climara patch since 2003 with no problem sticking but now since later 2020 I have a terrible problem on wrinkling and coming off. I know why, they have cut down on the thickness of the plastic so therefore are putting less glue or what ever they put to stick on the patch, they're saving money but causing us [problems. Now I have to put a large banded over the patch to make sure it will stay on. I have called the company and reported it to my drug store CVS now have to wait to see what they will do."

8 / 10
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24 Report
  • txtalk
  • October 14, 2012

Vivelle-Dot (estradiol) for Postmenopausal Symptoms "I had a total hysterectomy and experienced terrible hot flashes. I began with a dosage of .05 but the hot flashes continued, although less severe. My doctor changed the dosage to .1 and the hot flashes are a thing of the past. I've only been on this medication for 3 months but haven't experienced any side effects so far."

9 / 10
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62 Report
  • Kords...
  • March 26, 2017

For Postmenopausal Symptoms "At 46, I had a Total Abdominal hysterectomy 6 months ago due to adenomyosis and severe endometriosis. Had no hormone therapy at first the doctor took a wait and see approach. One month ago I started having intense hot flashes and joint inflammation. Doctor prescribed 1 mg estradiol a week ago and I noticed my symptoms vanished almost completely by day 2. I learned after trial in error that taking it in the morning works best for me as it gives me a ton of energy. I'm starting to feel human again."

10 / 10
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43 Report
  • Anonymous
  • Taken for less than 1 month
  • September 27, 2016

For Postmenopausal Symptoms "I have been using Estradiol for a week now and I only wish I would have gone and seen my doctor sooner. After one day I could tell a difference with my moods. I don't feel so wired or on edge any more. I did not notice my mood swings but I'm sure my family did...lol My hot flashes are gone. Thank you!"

10 / 10
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44 Report
  • Elaine
  • Taken for 5 to 10 years
  • September 11, 2014

Estrace (estradiol) for Hypoestrogenism "I had a total/full Hysterctomy in Jan of 2006. I was put on Estrace/Estradoil 1mg at the time. Pending on the person, we are all different. 1 mg, I still had bad hot flashes, terrible or nasty temper, dizziness, feeling faint, very moody, feelings of rage. My Gyn put me up to a 2mg tablet. It worked, the rage feelings, dizziness, and most of the sweating and hot flashes eased or went away. I felt human again, and in control of my thoughts, and actions. It feels good not to have that terrible rage. I was at this time not receiving the right dose, it was to low. This week my gyn put me back on 1mg of Estrace, all those horrible feelings came back and quickly. My body again, was not getting enough hormone of estrogen and back on 2mg's."

10 / 10
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53 Report
  • menop...
  • Taken for 1 to 6 months
  • February 25, 2023

Estraderm (estradiol) for Postmenopausal Symptoms "First time using these patches this month and they are absolutely awful They keep falling off, and will not stay on for the 3 days. Been using other brand patches for over a year and never had this problem. Definitely not fit for purpose."

1 / 10
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11 Report
  • Flash...
  • Taken for 6 months to 1 year
  • June 4, 2019

Estradiol Patch (estradiol) for Postmenopausal Symptoms "The Alvogen small, clear, thin patches worked very well. For some time, my pharmacy has been filling my prescription with Mylan. As a medication, I notice no difference. But I hate the Mylan patches anyway because they are large, thick, brown, and irritate my skin far more and far longer than the Alvogen. Clearly this is a shared experience. Will Mylan take note?"

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32 Report
  • godde...
  • Taken for 10 years or more
  • January 19, 2013

Vivelle-Dot (estradiol) for Oophorectomy "I had ovarian cancer and had an oopherectomy, my oncologist wanted me to use this drug for at least 10 years, started with higher dose and have gone down to 0.05, have tried dropping it to 0.025, but noticed I was having the hot flashes and lack of sleep at night, gone back to the 0.05 and enjoy it so much more, although I am now going on my 12th year of taking it. Trying to wean off of it but without the ovaries it is hard. Love this patch!!"

10 / 10
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59 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.