User Reviews for Pristiq
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Pristiq.
Reviews for Pristiq to treat Depression
Review by MissArtVandelay (taken for less than 1 month):
On my first day of Pristiq, I noticed an immediate surge of energy (coupled with a racing heart and a feeling of disorientation). I am somewhat sensitive to mediciations generally so I was prepared to inherit some of the side effects. What I have experienced in my first week is tiredness, irritability/difficult sleeping, grinding teeth, nausea (vomited 5 times on night 1, which settled on second day), loss of appetite and general stiffness around my neck and back. I trust these symptoms will settle in the coming weeks but thought it may be valuable to share my first week, for those who are a little sensitive to medication. In regards to my mental state, I can safely say my mood has been moderately chilled, unfazed and without any anxiety.
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January 20, 2015 7:12 PM
Review by Glad to be back:
Was totally down in the dumps for some reason even though my life was great. Finally I could take no more as my mind was giving me nasty thoughts to end things. Immediately went to the doctors and he prescribed me 50 mg Pristiq which sent my mind out of control. Now my whole being was in trouble and refusing to go to work and being around my family. Immediately back to the doctors to be put on 100 mg and I can say I have never looked back. Totally changed my life as I am myself again. Yeah a few sexual side effects but I can live with that I'm just glad to be back .
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January 1, 2015 1:59 AM
Review by fkgajaohbv:
My wife unexpectedly told me she wanted a divorce and I was devastated. We have two small boys. I instantly saw a psychiatrist who prescribed me 50 mg of Pristiq. It seemed to help somewhat but I would still breakdown into hysterical crying fits. After 15 days she put me on 100 mg and I've been fine ever since. I feel like I can deal with this now. I have not had any negative side effects, except shaking my leg. I do have insomnia but I had that from the anxiety of the divorce and I'm prescribed something to help me sleep. I can't say for sure if the Pristiq causes the insomnia, but I do feel a little amped. Overall, it's better than I thought as I generally don't feel like I'm on something and feel like myself.
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December 29, 2014 2:16 PM
Review by trixieLb:
I have been on Pristiq for about 3 months. I had insane anxiety and depression as well as insomnia that got so bad I ended up in the ER. I don't care if I ever come off of Pristiq because it works. I am normal again. I sleep, and for about 2 months I almost forgot what it was like to feel so anxious I could hardly function at work or life. I hesitated to start this medicine because my psychiatrist told me absolutely no drinking. I do have a few drinks on weekends and have no side effects from it.
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December 18, 2014 7:40 PM
Review by dbugg91:
Pristiq for me is a life saver! The fist 2 days I took the medication I was tired, but now being on it for two weeks it is amazing. I used to cry at the drop of a hat, and I had severe anxiety. Pristiq is the only medication that has ever worked for me! Try it! It might save your life too!
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December 11, 2014 2:51 PM
Review by ccsk (taken for 1 to 2 years):
I have had depression for a long time, sometimes more serious, sometimes less serious. In the past 7 years, I think I experience a "re-entry shock" going back to the teaching profession in HK. I need to take it once per day. I did not experience any side effect like sleepiness, dizziness. I can perform my normally heavy duties in my workplace. At first my doctor ask me to take it after evening, but since it will not affect my work and need not be taken after meals, I prefer to take it right after I get up, and I can establish a routine for it easily. Soon after I have taken Pristig, all my negative thoughts and feelings disappear like miracle and many people around me commented that I am happier than before.
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December 9, 2014 11:24 PM
Review by Amanda_GT:
Finally I see hope. After being diagnosed with severe depression (took me 4 years to seek treatment), I tried 5 different medications (plus therapy). They all failed miserably and I lost the hope I didn't even know I had, then tried suicide twice. Finally I was prescribed Pristiq and let me just say... what a difference! It got easier to wake up and get through the day, my self-esteem got better, my anxiety doesn't come as often, and I can even make plans for the future. For the first time I see change is possible. Just don't ever forget to take your pills, you can't really function without them. I got no side effects except for increased hunger/libido, and a bit of difficulty falling asleep. I'm taking 150mg now.
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December 3, 2014 3:45 PM
Review by skisiks (taken for 1 to 2 years):
I have forgot to take a couple of times. I am not able to function if I skip I have to go to doctor and beg for more if I run out. I am going to ask to be taken off this medicine and prescribed something else. My last experience was horrible. I ran out for 1 night and when I awoke I was falling everywhere and could not get it under control until I took a pill.
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November 26, 2014 9:25 PM
Review by Retroesque (taken for 1 to 6 months):
Started 12 weeks ago on 50mg stuck it out for 7 weeks - not much change and decided to step up to 100mg - 5 weeks later can say a change has arrived in the last 10 days and I am over the moon. I have refused medication all my life - this was a massive decision for me ... I wish now I'd done it years ago. Critical voice gone, anxiety close to gone, depression lifting, motivation returning - hope and dreams coming back. I now laugh, play jokes and manage stress 'normally'. I have to take care to get enough sleep - some days I am still really exhausted, but that is lifting. The side effects were as expected, dry mouth, need to eat regularly, headaches and perhaps a little sleep issues - but compared to life before they are well worth it.
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November 11, 2014 12:01 PM
Review by JeffR02:
I've been on Pristiq for just over a month, and I don't have the desire to do anything. I have gone days without shaving or taking a bath. I feel like a zombie unable to make decisions or take care of myself and my home. I find myself seating all day on my sofa, and sleeping most of the day-My appetite has increased and now my weight gone up rapidly. After reading a recent post on this medication, I was shocked to learn that only one other person, has had the same experienced. I am quoting this medication, today.
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October 29, 2014 1:13 PM
Review by ElizaNYC:
This medicine saved my sanity. I had crippling anxiety/panic attack disorder that forced me to take a year and a half off of college. I was a complete and total wreck. After a year and a half of rest/therapy I decided I was ready to go back to school, within 3 weeks I was totally crumbling, and was completely overwhelmed (anxiety disorder I had worked so hard to treat was rearing its ugly head). I was scared to try another med because my old one made me gain 55lbs (despite dieting), but at this point I was so desperate. My psychiatrist gave me Pristiq and BAM a week later I was like a different person. No more constant crying and confusion. Now 10 months later I am doing really well in school and have lost 40lbs.
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October 23, 2014 6:27 PM
Review by odat:
Went from 50mg to 100mg. After 3 weeks on 50mg trying to adjust. Not getting results with tears or compulsive behavior like eating. Side effects of face flushing and hot flashes, anxiety is worse. It hasn't been 30 days on the change yet. Feel crazy.
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September 24, 2014 9:49 PM
Review by Anonymous:
I want to share my experience because I was terrified when I first started Pristiq. It was the first time I'd taken an antidepressant following a severe depressive episode. I read so many negative things about Pristiq and people over analysing it. It took 6 weeks to work and yes I had dry mouth, headaches and nausea but they passed after a few days. The anxiety went away gradually and I felt like I could control it again. The depression lifted too and I could function. I went cold turkey to come off it (Dr supervised) and yep side effects but no big deal. The brain zaps were full on but they lasted about 4 days. I feel great. Of course I'm doing lots of exercise and eating well too...but Pristiq helped.
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August 19, 2014 6:04 PM
Review by Root Beer Girl (taken for 6 months to 1 year):
This medicine has been very helpful to me. I started having extreme anxiety when I started taking Latuda. For two years I dealt with depression, severe anxiety and killer side effects from the SSRI (avoid them). In 2014 I finally said "ENOUGH!" I was a little scared to try a different medicine but life was so terrible I was willing to get some relief. I did not have any side effects when started taking the medicine. Pristiq has given some of my life back. I can function at the day program (which was in jeopardy before Pristiq) I highly recommend this medicine for those who suffer from depression and anxiety, at lease give it a try.
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August 17, 2014 2:48 AM
Review by Diggster (taken for 6 months to 1 year):
Was on Pristiq about a year ago, got of it due to, being totally grey, NO highs - No lows limited high happy moments. I know its supposed to level your moods. But I wanted off it. I weaned myself of it by buying a steel bladed pill cutter, cut the pill into
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August 16, 2014 8:26 AM
Review by Anonymous (taken for 1 to 6 months):
Bad withdrawal symptoms when trying to quit. I had horrible depression when trying to wean off. Also didn't like how I felt on it. Took my imagination away, ability to day dream. Gave me high blood pressure. You must get on medicines for high blood pressure. So either stop Pristiq or get high blood pressure meds if you need it.
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July 31, 2014 4:56 AM
Review by livebyfaith (taken for less than 1 month):
I used Pristiq to treat anxiety/panic/depression after trying a few other meds that didn't work well a few years ago. Cymbalta was one that did work better when trying to find the right one but not quite as well. I eventually switched to Prozac due to cost, after that worked well for a year or two and eventually tapered off medicines all together. Had another episode and tried Prozac again and then Celexa, neither of which worked well. I just switched back to Pristiq and feel like I can literally tell the difference after only a day. I do know you need to take each day and at the same time to avoid withdrawal symptoms but I was able to get off it pretty easy in the past by switching to Prozac and then tapering. Hoping for the best!
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July 28, 2014 2:20 PM
Review by amybintn:
I've been taking 50 mg Pristiq in combination with 300 mg Wellbutrin for two weeks, and it's the best I've tried. This week I've been able to handle family and work issues with a sense of hope and able to focus rather than anxiety/ worrying, and that's awesome. I had been taking Prozac and Wellbutrin for years but felt it wasn't working. I tried everything but other meds didn't work or had bad side effects. This made me queasy at first, but my dr. had said that would get better, and it did. I take it at night because in the morning, it makes me tired. So don't give up! There is hope. Hang in there.
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July 26, 2014 1:52 PM
Review by Alicemcn5:
Diagnosed with Cyclothymia, as severely depressed and adult ADHD. Been on Pristiq for 2 years, before that Cymbalta. Although both worked well, Pristiq has helped much more (no meds for ADHD). Had to have the dosage raised today because I must have hit a plateau and started feeling bad again. Doc says the higher dosage for six weeks should help get me back on track and then I can take the regular dose again. For anyone that has quit these medicines cold turkey, please don't do it, can cause seizures/psychotic episodes, talk to doctor. I'll be on these meds or something all my life, so feeling better-no complaints. I'm actually nicer on Pristiq and since I don't take anything for ADHD I'm still very interesting too.
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July 11, 2014 5:16 PM
Review by jji:
I could accept things better.
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June 18, 2014 8:41 PM
Review by Mel Down:
I have tried 3 different antidepressants throughout my life & I have been on Pristiq for a year now. It worked really well to help my depression but 2 downfalls for me are massively low libido and withdraws before the tablet is due to be taken. Tingling, slow vision, what seems like electric currents going off in my head. Weaning off will be the biggest challenge due to rapid onset of side effects. I have read from people who tried to wean off them & failed because they were quite unwell.
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June 4, 2014 7:54 AM
Review by kiji:
I have never been so sick on a medicine in all of my life. Perhaps I don't handle SNRIs well. I felt completely out of body, threw up, and am dealing with after effects of coming off cold turkey. If you're sensitive to medicines, don't take this. There is only 1 dose which means jumping right on to the high "therapeutic" dose without tapering up. Scary! You're better off coming up slowly on a medicine that can be slowly tapered up and down.
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May 28, 2014 3:08 PM
Review by Ga girl (taken for less than 1 month):
Been off/on antidepressants for 20 years. Been on 100 mg of Zoloft for about 5 years now and was having some adverse effects- gained a lot of weight for starters. Started Pristiq about 3 weeks ago. I feel a lot clearer in the mind- guess I didn't realize the Fog I was in on the Zoloft. I'm not hungry- lost seven pounds in the first two weeks. Had some headaches while switching over. Sleep hasn't been a problem- but I have found that I need to take the meds at the same time in the mornings or I have headaches. So far, so good. Hopefully it will continue long term. I will probably be on meds the rest of my life- I've come to terms with that. Hoping this will be the last one I'm on!
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May 27, 2014 3:06 PM
Review by TulsaXOGirl:
My Psychiatrist put me in 50mg Pristiq for compulsive, regular binge eating and anxiety/depression. The first week I was on it, my anxiety-ridden thoughts about food changed completely and I lost interest in binge eating, so I have lost a few pounds so far. I was extremely happy, with virtually no anxiety. I am now on week 2, and the anxiety is starting to creep back in and I'm not quite as happy, so I will be discussing increasing my dosage with my doctor. The loss of interest in food has persisted. Overall, I think this medication is great and I plan to stay on it.
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May 9, 2014 9:50 AM
Review by BRMAN (taken for 1 to 6 months):
I took 50mg pills for almost 5 months. I could feel the improvement in my mood and in my life as a consequence. No sexual side-effects. Unfortunately I had to stop because it was causing severe hair-loss (alopecia).
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March 24, 2014 7:26 PM
Learn more about Depression
Micromedex® Care Notes:
- Depression After Spinal Cord Injury
- Depression In Children, Ambulatory Care
- Depression, Ambulatory Care
Related encyclopedia articles:
- Adjustment disorder
- Aging changes in sleep
- Chemical dependence - resources
- Depression - older adults
- Depression - overview
- Depression - resources
- Loss of a spouse - resources
- Major depression
- Seasonal affective disorder
- Stress management
Drugs.com Health Center:
More about Pristiq (desvenlafaxine)
- Other brands: Khedezla