User Reviews for Pristiq
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Pristiq.
Reviews for Pristiq to treat Depression
Review by JeffR02:
I've been on Pristiq for just over a month, and I don't have the desire to do anything. I have gone days without shaving or taking a bath. I feel like a zombie unable to make decisions or take care of myself and my home. I find myself seating all day on my sofa, and sleeping most of the day-My appetite has increased and now my weight gone up rapidly. After reading a recent post on this medication, I was shocked to learn that only one other person, has had the same experienced. I am quoting this medication, today.
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October 29, 2014 1:13 PM
Review by odat:
Went from 50mg to 100mg. After 3 weeks on 50mg trying to adjust. Not getting results with tears or compulsive behavior like eating. Side effects of face flushing and hot flashes, anxiety is worse. It hasn't been 30 days on the change yet. Feel crazy.
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September 24, 2014 9:49 PM
Review by Anonymous:
I want to share my experience because I was terrified when I first started Pristiq. It was the first time I'd taken an antidepressant following a severe depressive episode. I read so many negative things about Pristiq and people over analysing it. It took 6 weeks to work and yes I had dry mouth, headaches and nausea but they passed after a few days. The anxiety went away gradually and I felt like I could control it again. The depression lifted too and I could function. I went cold turkey to come off it (Dr supervised) and yep side effects but no big deal. The brain zaps were full on but they lasted about 4 days. I feel great. Of course I'm doing lots of exercise and eating well too...but Pristiq helped.
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August 19, 2014 6:04 PM
Review by Root Beer Girl (taken for 6 months to 1 year):
This medicine has been very helpful to me. I started having extreme anxiety when I started taking Latuda. For two years I dealt with depression, severe anxiety and killer side effects from the SSRI (avoid them). In 2014 I finally said "ENOUGH!" I was a little scared to try a different medicine but life was so terrible I was willing to get some relief. I did not have any side effects when started taking the medicine. Pristiq has given some of my life back. I can function at the day program (which was in jeopardy before Pristiq) I highly recommend this medicine for those who suffer from depression and anxiety, at lease give it a try.
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August 17, 2014 2:48 AM
Review by Diggster (taken for 6 months to 1 year):
Was on Pristiq about a year ago, got of it due to, being totally grey, NO highs - No lows limited high happy moments. I know its supposed to level your moods. But I wanted off it. I weaned myself of it by buying a steel bladed pill cutter, cut the pill into
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August 16, 2014 8:26 AM
Review by Anonymous (taken for 1 to 6 months):
Bad withdrawal symptoms when trying to quit. I had horrible depression when trying to wean off. Also didn't like how I felt on it. Took my imagination away, ability to day dream. Gave me high blood pressure. You must get on medicines for high blood pressure. So either stop Pristiq or get high blood pressure meds if you need it.
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July 31, 2014 4:56 AM
Review by livebyfaith (taken for less than 1 month):
I used Pristiq to treat anxiety/panic/depression after trying a few other meds that didn't work well a few years ago. Cymbalta was one that did work better when trying to find the right one but not quite as well. I eventually switched to Prozac due to cost, after that worked well for a year or two and eventually tapered off medicines all together. Had another episode and tried Prozac again and then Celexa, neither of which worked well. I just switched back to Pristiq and feel like I can literally tell the difference after only a day. I do know you need to take each day and at the same time to avoid withdrawal symptoms but I was able to get off it pretty easy in the past by switching to Prozac and then tapering. Hoping for the best!
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July 28, 2014 2:20 PM
Review by amybintn:
I've been taking 50 mg Pristiq in combination with 300 mg Wellbutrin for two weeks, and it's the best I've tried. This week I've been able to handle family and work issues with a sense of hope and able to focus rather than anxiety/ worrying, and that's awesome. I had been taking Prozac and Wellbutrin for years but felt it wasn't working. I tried everything but other meds didn't work or had bad side effects. This made me queasy at first, but my dr. had said that would get better, and it did. I take it at night because in the morning, it makes me tired. So don't give up! There is hope. Hang in there.
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July 26, 2014 1:52 PM
Review by Alicemcn5:
Diagnosed with Cyclothymia, as severely depressed and adult ADHD. Been on Pristiq for 2 years, before that Cymbalta. Although both worked well, Pristiq has helped much more (no meds for ADHD). Had to have the dosage raised today because I must have hit a plateau and started feeling bad again. Doc says the higher dosage for six weeks should help get me back on track and then I can take the regular dose again. For anyone that has quit these medicines cold turkey, please don't do it, can cause seizures/psychotic episodes, talk to doctor. I'll be on these meds or something all my life, so feeling better-no complaints. I'm actually nicer on Pristiq and since I don't take anything for ADHD I'm still very interesting too.
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July 11, 2014 5:16 PM
Review by jji:
I could accept things better.
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June 18, 2014 8:41 PM
Review by Mel Down:
I have tried 3 different antidepressants throughout my life & I have been on Pristiq for a year now. It worked really well to help my depression but 2 downfalls for me are massively low libido and withdraws before the tablet is due to be taken. Tingling, slow vision, what seems like electric currents going off in my head. Weaning off will be the biggest challenge due to rapid onset of side effects. I have read from people who tried to wean off them & failed because they were quite unwell.
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June 4, 2014 7:54 AM
Review by kiji:
I have never been so sick on a medicine in all of my life. Perhaps I don't handle SNRIs well. I felt completely out of body, threw up, and am dealing with after effects of coming off cold turkey. If you're sensitive to medicines, don't take this. There is only 1 dose which means jumping right on to the high "therapeutic" dose without tapering up. Scary! You're better off coming up slowly on a medicine that can be slowly tapered up and down.
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May 28, 2014 3:08 PM
Review by Ga girl (taken for less than 1 month):
Been off/on antidepressants for 20 years. Been on 100 mg of Zoloft for about 5 years now and was having some adverse effects- gained a lot of weight for starters. Started Pristiq about 3 weeks ago. I feel a lot clearer in the mind- guess I didn't realize the Fog I was in on the Zoloft. I'm not hungry- lost seven pounds in the first two weeks. Had some headaches while switching over. Sleep hasn't been a problem- but I have found that I need to take the meds at the same time in the mornings or I have headaches. So far, so good. Hopefully it will continue long term. I will probably be on meds the rest of my life- I've come to terms with that. Hoping this will be the last one I'm on!
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May 27, 2014 3:06 PM
Review by TulsaXOGirl:
My Psychiatrist put me in 50mg Pristiq for compulsive, regular binge eating and anxiety/depression. The first week I was on it, my anxiety-ridden thoughts about food changed completely and I lost interest in binge eating, so I have lost a few pounds so far. I was extremely happy, with virtually no anxiety. I am now on week 2, and the anxiety is starting to creep back in and I'm not quite as happy, so I will be discussing increasing my dosage with my doctor. The loss of interest in food has persisted. Overall, I think this medication is great and I plan to stay on it.
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May 9, 2014 9:50 AM
Review by BRMAN (taken for 1 to 6 months):
I took 50mg pills for almost 5 months. I could feel the improvement in my mood and in my life as a consequence. No sexual side-effects. Unfortunately I had to stop because it was causing severe hair-loss (alopecia).
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March 24, 2014 7:26 PM
Review by vmart085 (taken for 1 to 6 months):
I rated Pristiq a 9 for the simple fact that although it was really helped me get out of depression, I have been having crazy vivid dreams. The dreams are not pleasant, or bad, just weird. I have flashbacks about them all through the day, and I can recall almost every little detail. Some might argue that this is not a bad side effect, however, because of this, I've been having poor sleep. All this said, it wouldn't be a reason for me to get off the medication. It has really given me back my life!
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March 12, 2014 9:08 AM
Review by dotts:
I have been ON EVERYTHING even when it was in test study, Prozac, etc. After being on the test study for Pristiq I begged to be put on it on a regular basis. I sleep 7-8 hours per night uninterrupted, I am high performance on my job, I have a renewed life even including exercise. However this medicine is a 4 tier on my Blue Cross supplemental and it is very expensive for a 90 day supply.
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March 3, 2014 10:16 PM
Review by Tim123:
I had been on Pristiq for about 1 year at 50mg. While on it, the feelings of depression and anxiety pretty much disappeared. However, after changing my lifestyle for the better and going off Pristiq I have been dealing with withdrawal side effects. It has been 4 weeks now and I still have the brain zaps which make me feel unsteady. These zaps have been continuous and extremely upsetting. Add to this the deep states of sadness (mention the least sad thing and I would start crying) and the nightmares....it has been a very rough 4 weeks. For the last week I have had blood pressure swings from 110/60 to 218/111 and weakness in the large muscles of my legs and arms. For those going on or off, be careful!
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February 28, 2014 9:10 AM
Review by Devilboy77 (taken for 1 to 6 months):
I have been taking this medication for 2 months, the first month I suffered almost all of the side effects from loss of appetite, headaches, dizziness, loss of concentration, loss of sex drive and not sleeping. 2 month in and I find myself having episodes of feeling really angry and crying for no reason and to the point of not eating and just sleeping. I am seeing a psychologist and am yet to discuss with them why I am still feeling depressed and now angry with or at myself.
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February 26, 2014 10:34 PM
Review by jahnj82a (taken for 6 months to 1 year):
I was desperate for something that would get me out of the dark abyss that is anxiety and depression, and get rid of the constant thoughts of suicide. I turned to Pristiq - it was new, and made out to be a miracle. And it was. I had no side effects when I started taking it. I was able to get back to work and perform better in school. Everything seemed great. I had my life back. Until, months later, I went my first day without it. The withdrawal symptoms were crippling. Paranoia, a pounding headache, vertigo, and sweating are just a few of the symptoms I experienced in my withdrawal. The headache was so severe I could do nothing but lie down. I still take. Too difficult to quit.
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February 24, 2014 9:28 PM
Review by 151Kat (taken for 6 months to 1 year):
I started taking Pristiq 50mg for Major Depression, major anxiety, Chronic pain. I took it first day and it was GREAT! First week sleep, headaches were rough but energy was good. Gradually started decreasing by itself as I kept taking the pills. 9 month's later I was still taking the pills but I was dizzy, getting brain zaps, CRS, tinnitus, major anxiety, non-stop migraine for 2 months, bed rest, and had to go to psych hospital. Psych. MD upped to 100mg Pristiq that lasted a week. My whole spine was HURTING and now I am switching over to a new SNRI that I am not happy about. And still on withdrawal from Pristiq.
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February 17, 2014 1:14 PM
Review by sbbt:
I took Pristiq for the first time today. Along side of Deplin and ADD medication. I thought it would be a good idea to take all this at night. Not so much. I am wide awake and have to start getting ready for work in 2 and a half hours. I have struggled with depression and anxiety for years now. But I must say today has been one of the best days I have had in a long time. I am sure me making a change in the right direction has something to do with it but still very happy and excited. I have had yawning already which I have experienced before on anti - depressants and I also have dry mouth. I have a pretty good cocktail going on but it had to be done.
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February 14, 2014 3:30 AM
Review by kt124 (taken for 1 to 6 months):
I was diagnosed with anxiety and major depression just over a year ago. I am a 19 year old female and have a very difficult family situation. I first tried Cipralex which made me really irritable, then I tried Wellbutrin which gave me a rash. I was then on Cymbalta for 6 months, but I had many side effects and was exhausted. Within the first week on Pristiq I began to notice a huge difference, much more energy. A month later I almost feel like my old self, lots of energy, I can control my own thoughts, and I can concentrate which is amazing because I'm in university. I'm so glad I finally found something that works for me, and I'm looking forward to more improvements over time.
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January 27, 2014 12:13 AM
Review by Zyut (taken for 5 to 10 years):
After a severe injury in the workplace, I hit rock bottom, depressed, suicidal, hopeless, really sad. I didn't understand what was going on, like someone else was at the wheel and I had to go along on this scary ride. I needed help so went to a psychiatrist who diagnosed clinical Depression, this was a relief to hear and separated me from the weirdo driving! Took 2 years of counseling and different medicines to find the right one, for me it is Pristiq. I have been on it for 8 years and now work full time. I think it takes a while for the user to live with an anti-depressant medication, I read and hear of many who want out after 2-4 years, but I found that just hanging in there is the way to go. I see myself as complete now, no side effects.
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January 26, 2014 3:28 PM
Review by Kevin8888:
Went to the doctor complaining of anxiety. Was waking up and not falling back asleep or even worse could not fall asleep. Was also having anxiety attacks. The last time this happened I was prescribed effexor which was a nightmare and Celexa which did nothing for me. Ended up quitting my job and with time off I returned to normal. Quitting my job this time is not a option so the doctor put me on Pristiq. Noticed a positive effect within 7 days and I have been on it for a month now. This drug has worked absolute wonders for me. I have had no side effects at all (and no sexual impotency).
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January 23, 2014 7:27 PM
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More about Pristiq (desvenlafaxine)
- Other brands: Khedezla