User Reviews for Pristiq
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Pristiq.
|Major Depressive Disorder||7 reviews||44 medications|
|Depression||452 reviews||75 medications|
|Summary of Pristiq reviews||459 reviews||7.5|
Reviews for Pristiq
Review by MissArtVandelay (taken for less than 1 month):
For Depression: On my first day of Pristiq, I noticed an immediate surge of energy (coupled with a racing heart and a feeling of disorientation). I am somewhat sensitive to mediciations generally so I was prepared to inherit some of the side effects. What I have experienced in my first week is tiredness, irritability/difficult sleeping, grinding teeth, nausea (vomited 5 times on night 1, which settled on second day), loss of appetite and general stiffness around my neck and back. I trust these symptoms will settle in the coming weeks but thought it may be valuable to share my first week, for those who are a little sensitive to medication. In regards to my mental state, I can safely say my mood has been moderately chilled, unfazed and without any anxiety.
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January 20, 2015 7:12 PM
Review by 24 year old female (taken for less than 1 month):
For Major Depressive Disorder: The first two days on Pristiq I felt really heavy and out of it. I knew it was working when the initial shock to my body passed - I was ready to give something a chance for my anxiety and major depression. So, two weeks on it I'm starting to feel a lot happier. but there has been some slight apprehension along the way due to some side effects: constipation and worried about other potential SE's from SNRI's but this medication seems to be pretty mild (50mg) and has been helping to level out my Serotonin - norepinephrine levels.
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January 9, 2015 2:17 AM
Review by Glad to be back:
For Depression: Was totally down in the dumps for some reason even though my life was great. Finally I could take no more as my mind was giving me nasty thoughts to end things. Immediately went to the doctors and he prescribed me 50 mg Pristiq which sent my mind out of control. Now my whole being was in trouble and refusing to go to work and being around my family. Immediately back to the doctors to be put on 100 mg and I can say I have never looked back. Totally changed my life as I am myself again. Yeah a few sexual side effects but I can live with that I'm just glad to be back .
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January 1, 2015 1:59 AM
Review by fkgajaohbv:
For Depression: My wife unexpectedly told me she wanted a divorce and I was devastated. We have two small boys. I instantly saw a psychiatrist who prescribed me 50 mg of Pristiq. It seemed to help somewhat but I would still breakdown into hysterical crying fits. After 15 days she put me on 100 mg and I've been fine ever since. I feel like I can deal with this now. I have not had any negative side effects, except shaking my leg. I do have insomnia but I had that from the anxiety of the divorce and I'm prescribed something to help me sleep. I can't say for sure if the Pristiq causes the insomnia, but I do feel a little amped. Overall, it's better than I thought as I generally don't feel like I'm on something and feel like myself.
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December 29, 2014 2:16 PM
Review by trixieLb:
For Depression: I have been on Pristiq for about 3 months. I had insane anxiety and depression as well as insomnia that got so bad I ended up in the ER. I don't care if I ever come off of Pristiq because it works. I am normal again. I sleep, and for about 2 months I almost forgot what it was like to feel so anxious I could hardly function at work or life. I hesitated to start this medicine because my psychiatrist told me absolutely no drinking. I do have a few drinks on weekends and have no side effects from it.
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December 18, 2014 7:40 PM
Review by dbugg91:
For Depression: Pristiq for me is a life saver! The fist 2 days I took the medication I was tired, but now being on it for two weeks it is amazing. I used to cry at the drop of a hat, and I had severe anxiety. Pristiq is the only medication that has ever worked for me! Try it! It might save your life too!
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December 11, 2014 2:51 PM
Review by ccsk (taken for 1 to 2 years):
For Depression: I have had depression for a long time, sometimes more serious, sometimes less serious. In the past 7 years, I think I experience a "re-entry shock" going back to the teaching profession in HK. I need to take it once per day. I did not experience any side effect like sleepiness, dizziness. I can perform my normally heavy duties in my workplace. At first my doctor ask me to take it after evening, but since it will not affect my work and need not be taken after meals, I prefer to take it right after I get up, and I can establish a routine for it easily. Soon after I have taken Pristig, all my negative thoughts and feelings disappear like miracle and many people around me commented that I am happier than before.
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December 9, 2014 11:24 PM
Review by Amanda_GT:
For Depression: Finally I see hope. After being diagnosed with severe depression (took me 4 years to seek treatment), I tried 5 different medications (plus therapy). They all failed miserably and I lost the hope I didn't even know I had, then tried suicide twice. Finally I was prescribed Pristiq and let me just say... what a difference! It got easier to wake up and get through the day, my self-esteem got better, my anxiety doesn't come as often, and I can even make plans for the future. For the first time I see change is possible. Just don't ever forget to take your pills, you can't really function without them. I got no side effects except for increased hunger/libido, and a bit of difficulty falling asleep. I'm taking 150mg now.
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December 3, 2014 3:45 PM
Review by kbillz:
For Major Depressive Disorder: I want to start off my review by stating that everyone is different; so what worked for me may not work for you. With that said, I was suffering from severe MDD, anxiety, OCD, border lining on psychosis after I had my son last summer. I was so miserable for his first year of life, and then I was finally put on Pristiq after trying about 10 other anti-depressants/anxiety meds. I seriously feel like a normal person again. I can enjoy my family and friends, and am able to maintain my relationships with them. This has been a literal life saver for me, and because of this, I don't mind that my insurance doesn't cover it.
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December 3, 2014 1:24 PM
Review by skisiks (taken for 1 to 2 years):
For Depression: I have forgot to take a couple of times. I am not able to function if I skip I have to go to doctor and beg for more if I run out. I am going to ask to be taken off this medicine and prescribed something else. My last experience was horrible. I ran out for 1 night and when I awoke I was falling everywhere and could not get it under control until I took a pill.
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November 26, 2014 9:25 PM
Review by Anonymous (taken for 1 to 6 months):
For Major Depressive Disorder: Pristiq was a miracle for me. I was originally put on the 50mg and my mood drastically changed from depressed and anxious to happy and functioning. Do NOT forget to take it, though. I forgot to take a dose one day and I was a mess the whole day, and then when I finally took it again, it didn't work as well so I had to have the dosage doubled. Then I ran out and couldn't get in touch with my psychiatrist so I spent about a week off of it. Was extremely depressed and had to be watched closely by my family and boyfriend to make sure that I didn't hurt myself. Tried going back on it but it no longer worked. I'm not sure if I hadn't had those mishaps with taking it if I would still be on it but it was definitely a lifesaver while it worked.
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November 11, 2014 7:15 PM
Review by Retroesque (taken for 1 to 6 months):
For Depression: Started 12 weeks ago on 50mg stuck it out for 7 weeks - not much change and decided to step up to 100mg - 5 weeks later can say a change has arrived in the last 10 days and I am over the moon. I have refused medication all my life - this was a massive decision for me ... I wish now I'd done it years ago. Critical voice gone, anxiety close to gone, depression lifting, motivation returning - hope and dreams coming back. I now laugh, play jokes and manage stress 'normally'. I have to take care to get enough sleep - some days I am still really exhausted, but that is lifting. The side effects were as expected, dry mouth, need to eat regularly, headaches and perhaps a little sleep issues - but compared to life before they are well worth it.
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November 11, 2014 12:01 PM
Review by JeffR02:
For Depression: I've been on Pristiq for just over a month, and I don't have the desire to do anything. I have gone days without shaving or taking a bath. I feel like a zombie unable to make decisions or take care of myself and my home. I find myself seating all day on my sofa, and sleeping most of the day-My appetite has increased and now my weight gone up rapidly. After reading a recent post on this medication, I was shocked to learn that only one other person, has had the same experienced. I am quoting this medication, today.
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October 29, 2014 1:13 PM
Review by ElizaNYC:
For Depression: This medicine saved my sanity. I had crippling anxiety/panic attack disorder that forced me to take a year and a half off of college. I was a complete and total wreck. After a year and a half of rest/therapy I decided I was ready to go back to school, within 3 weeks I was totally crumbling, and was completely overwhelmed (anxiety disorder I had worked so hard to treat was rearing its ugly head). I was scared to try another med because my old one made me gain 55lbs (despite dieting), but at this point I was so desperate. My psychiatrist gave me Pristiq and BAM a week later I was like a different person. No more constant crying and confusion. Now 10 months later I am doing really well in school and have lost 40lbs.
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October 23, 2014 6:27 PM
Review by Bethkk (taken for less than 1 month):
For Major Depressive Disorder: I took Pristiq for one day. It was the most distressing experience ever. For about 48 hours, had blurry vision, jumpy eyes, dizziness, sweating, and kept changing moods every 5 minutes. First was crying, then felt high and was starring into space. Have taken Lexapro before and never felt anything remotely close to this horrible. This medicine was not for me.
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October 22, 2014 6:45 AM
Review by odat:
For Depression: Went from 50mg to 100mg. After 3 weeks on 50mg trying to adjust. Not getting results with tears or compulsive behavior like eating. Side effects of face flushing and hot flashes, anxiety is worse. It hasn't been 30 days on the change yet. Feel crazy.
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September 24, 2014 9:49 PM
Review by Anonymous:
For Depression: I want to share my experience because I was terrified when I first started Pristiq. It was the first time I'd taken an antidepressant following a severe depressive episode. I read so many negative things about Pristiq and people over analysing it. It took 6 weeks to work and yes I had dry mouth, headaches and nausea but they passed after a few days. The anxiety went away gradually and I felt like I could control it again. The depression lifted too and I could function. I went cold turkey to come off it (Dr supervised) and yep side effects but no big deal. The brain zaps were full on but they lasted about 4 days. I feel great. Of course I'm doing lots of exercise and eating well too...but Pristiq helped.
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August 19, 2014 6:04 PM
Review by Root Beer Girl (taken for 6 months to 1 year):
For Depression: This medicine has been very helpful to me. I started having extreme anxiety when I started taking Latuda. For two years I dealt with depression, severe anxiety and killer side effects from the SSRI (avoid them). In 2014 I finally said "ENOUGH!" I was a little scared to try a different medicine but life was so terrible I was willing to get some relief. I did not have any side effects when started taking the medicine. Pristiq has given some of my life back. I can function at the day program (which was in jeopardy before Pristiq) I highly recommend this medicine for those who suffer from depression and anxiety, at lease give it a try.
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August 17, 2014 2:48 AM
Review by Diggster (taken for 6 months to 1 year):
For Depression: Was on Pristiq about a year ago, got of it due to, being totally grey, NO highs - No lows limited high happy moments. I know its supposed to level your moods. But I wanted off it. I weaned myself of it by buying a steel bladed pill cutter, cut the pill into
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August 16, 2014 8:26 AM
Review by Anonymous (taken for 1 to 6 months):
For Depression: Bad withdrawal symptoms when trying to quit. I had horrible depression when trying to wean off. Also didn't like how I felt on it. Took my imagination away, ability to day dream. Gave me high blood pressure. You must get on medicines for high blood pressure. So either stop Pristiq or get high blood pressure meds if you need it.
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July 31, 2014 4:56 AM
Review by livebyfaith (taken for less than 1 month):
For Depression: I used Pristiq to treat anxiety/panic/depression after trying a few other meds that didn't work well a few years ago. Cymbalta was one that did work better when trying to find the right one but not quite as well. I eventually switched to Prozac due to cost, after that worked well for a year or two and eventually tapered off medicines all together. Had another episode and tried Prozac again and then Celexa, neither of which worked well. I just switched back to Pristiq and feel like I can literally tell the difference after only a day. I do know you need to take each day and at the same time to avoid withdrawal symptoms but I was able to get off it pretty easy in the past by switching to Prozac and then tapering. Hoping for the best!
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July 28, 2014 2:20 PM
Review by amybintn:
For Depression: I've been taking 50 mg Pristiq in combination with 300 mg Wellbutrin for two weeks, and it's the best I've tried. This week I've been able to handle family and work issues with a sense of hope and able to focus rather than anxiety/ worrying, and that's awesome. I had been taking Prozac and Wellbutrin for years but felt it wasn't working. I tried everything but other meds didn't work or had bad side effects. This made me queasy at first, but my dr. had said that would get better, and it did. I take it at night because in the morning, it makes me tired. So don't give up! There is hope. Hang in there.
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July 26, 2014 1:52 PM
Review by Jewish man:
For Major Depressive Disorder: I have fought depression for a long time and this is the first time in years that something has worked. I lost everything but now I can rebuild my life. Pristiq has been a miracle. I have taken many medicines and I was 100% sure nothing would work. Now with Gods help I have a new life. I felt nothing for first few weeks but after a month I'm alive. Thank you for developing this miracle. All the best. PLEASE BELIEVE ME, BEFORE THIS I WAS SURE NOTHING WOULD WORK AND I WAS SUICIDAL. FEW WEEKS AGO I WOULD HAVE TOLD LIVING IS THE WORST THING POSSIBLE BUT NOW IT WORKS, MY BRAIN DOES NOT WANT TO SLEEP ALL WEEK AND LOOSE EVERYTHING AND BE HOMELESS. PLEASE DON'T GIVE UP. YOU ARE HERE FOR A PURPOSE.
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July 24, 2014 4:15 AM
Review by Kristylyn:
For Major Depressive Disorder: I'm on 200 mg a day... It worked for the first few years but of late I'm not doing so well
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July 12, 2014 5:11 AM
Review by Alicemcn5:
For Depression: Diagnosed with Cyclothymia, as severely depressed and adult ADHD. Been on Pristiq for 2 years, before that Cymbalta. Although both worked well, Pristiq has helped much more (no meds for ADHD). Had to have the dosage raised today because I must have hit a plateau and started feeling bad again. Doc says the higher dosage for six weeks should help get me back on track and then I can take the regular dose again. For anyone that has quit these medicines cold turkey, please don't do it, can cause seizures/psychotic episodes, talk to doctor. I'll be on these meds or something all my life, so feeling better-no complaints. I'm actually nicer on Pristiq and since I don't take anything for ADHD I'm still very interesting too.
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July 11, 2014 5:16 PM
Learn more about
Micromedex® Care Notes:
- Depression After Spinal Cord Injury
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- Depression, Ambulatory Care
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Drugs.com Health Center:
More about Pristiq (desvenlafaxine)
- Other brands: Khedezla