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Cyclobenzaprine for Fibromyalgia User Reviews

Brand names: Amrix Comfort Pac with Cyclobenzaprine

Cyclobenzaprine has an average rating of 7.7 out of 10 from a total of 51 reviews for the off-label treatment of Fibromyalgia. 78% of reviewers reported a positive experience, while 16% reported a negative experience.

Cyclobenzaprine rating summary

7.7/10 average rating

51 ratings from 57 user reviews.

Compare all 27 medications used in the treatment of Fibromyalgia.

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Reviews for Cyclobenzaprine

  • Tammy
  • January 10, 2015

Flexeril (cyclobenzaprine) "Finally! Something that actually works. I've been diagnosed with fibromyalgia almost 2 years ago now and have been on Lyrica and Cymbalta with little relief. My doctor added Flexeril 3 days ago and I am in heaven! I have not felt rested in a very long time and my pain seems to be diminished somewhat. I really feel good and have actually smiled ALL day today. I sure hope this keeps up! Yay for Flexeril!"

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  • Anonymous
  • April 15, 2012

Flexeril (cyclobenzaprine) "It was very helpful for the spasms in my neck, shoulders, back, and hips. It took awhile before the muscles released. I weaned myself off the medicine and within 2 weeks was experiencing severe pain again. I'm back on now. I take 10 mg at night. It does make me tired in the morning but its worth it. I would recommend this for back pain and spasms. It helps to take it consistently."

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98 Report
  • Monda...
  • Taken for less than 1 month
  • March 14, 2020

"Stated taking cyclobenzaprine at a dose 5mg about 3 weeks ago for Fibro. Huge improvement. I'm back to playing pool and on the treadmill every 2nd day instead of being laid up and taking it easy for 2-3 days or longer. Showed the physical activity data from my phone to my doctor. He was sold on it. I am too. I've had 3 heart attacks (familial cholestemia) genetics. I need to be more active. Yeah I'm pleased with the reduction in my pain 30-50%. Still there but way more manageable and my mental health has definitely swung to a more happier outlook."

8 / 10
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43 Report

Frequently asked questions

  • MereR...
  • March 26, 2015

"I was diagnosed with fibromyalgia 7 years ago. I've taken this at night for probably 6 years now. It makes all the difference for me. It allowed me to start working out 5 years ago. I went from walking in a pool to running now, and I've even done several 5ks. A couple years ago I had another neurological pain condition develop that required me to take muscle relaxers during the day as well too. So I was put on a lighter weight (baclofen) muscle relaxer for during the day and to replace this at night. Within a few days of going off of this, I was so stiff I could barely walk. I ended up back on this for my evening dose, and within a couple days I was back to normal activity. So for me at least, this has worked better then anything."

10 / 10
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  • Anonymous
  • March 5, 2009

Flexeril (cyclobenzaprine) "Non-Restorative Sleep Disorder - After months of agony, the rheumatologist tried Flexeril on a 10 mg, once a day (before bed) regimen. Within a week, I felt better. Within two weeks, the symptoms were gone. Symptoms included: extreme fatigue, pain & swelling in both knees, pain & swelling in one wrist to the extent that the wrist was becoming deformed in appearance."

10 / 10
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97 Report

Are you taking this medicine?

  • Amary...
  • Taken for 5 to 10 years
  • July 25, 2016

"I have been on this medication off and on for several years and have had Fibromyalgia for over 20 years. Cyclobenzaprine along with Lyrica have allowed me to live a somewhat normal life. I get a far more restful sleep and am able to sleep through the night instead of waking every hour or so. My previous Doctor retired and it took me almost 2 years to find another . For 18 of those months I was without medications,( walk in clinics would not prescribe these medications) my quality of life diminished and I came very close to losing my job. Once I found a new Doctor and I was back on my medications, within a few weeks I was able to function again. For me Cyclobenzaprine and Lyrica have been the perfect combo to help manage my FM"

9 / 10
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55 Report
  • hurting...
  • December 20, 2011

Flexeril (cyclobenzaprine) "I took this and I found rest. True rest. I have been given so many scripts, none did anything for the tight muscle pain, or the seizing of my muscles, which I thought was it for me forever. I have been given extended release medicines for sleep, and nothing. It took a while for me to realize I was not sleeping at night because of my muscles not relaxing. I took this at 8 p.m. last night, and fell asleep, I woke up at like 12:45, My habit from long term spasms...but then I went right back to bed. Then I woke up, {I swear it was just because of habit again} at 3:45, I fell right back asleep. I finally woke up at 5:50 a.m for good. I could not tell you the last time I slept all night, and 6 in the morning is the latest I have slept in yrs. I have tried all types of medicines."

10 / 10
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More FAQ

  • Unres...
  • November 16, 2015

"Had fibromyalgia for over 10 years, very unrestful sleep. 2.5-5.0 mg of Cyclobenzaprine at night changed everything. I'm now able to get into deep sleep and stay there for 8 hours. Makes a world of difference in the pain and depression. Restful sleep is key to MANY disorders."

10 / 10
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51 Report
  • Anonymous
  • March 5, 2010

Amrix (cyclobenzaprine) "I was given this medication for fibromyalgia. Now at 21 years of age I am having heart problems. The first medication they took me off of after the heart problems surfaced was Amrix. Upon further research and communication with Amrix representatives I found that this medication is not supposed to be used for over a period of 3 weeks. Something my doctors obviously were unaware of. Just letting everyone out there know in case they find themselves in a similar situation."

2 / 10
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  • psymo...
  • Taken for 6 months to 1 year
  • December 9, 2016

"I have many debilitating conditions and have tried almost everything. My sensitive stomach only tolerates certain meds, such as Tramadol and cyclobenzaprine (Flexeril). I take 5mg early evening, sleep better than I have in years, and wake up the next day feeling better than I did before taking it. It's so nice to finally have some days where I do not wake up in debilitating pain, after a night of tossing and turning! I do not notice any side effects except for constipation, but I have IBS-C anyway so it's nothing new to me. If you have a lot of fibromyalgic or rheumatic pain, this is definitely worth a try. A little pill that does a lot!"

9 / 10
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  • Mckme
  • November 10, 2015

"I have always experienced a "bruising" type sensation when the least amount of pressure is applied to my fleshy areas, especially my legs and arms. I wrote this off as "just weird me". Additionally - I am extremely and overly TACTILE! One tiny invisible seam on the neck of a clothing tag can completely THROW ME OVER THE EDGE until it's cut out, ripped out or simply trashed! Same with sock seams...SOMETIMES EVERY INCH OF MY SKIN FELT BRUISED (which was not uncommon)- I did a simple Google search & FIBROMYALGIA popped up! Every symptom: incl. traumatic childhood causing dopamine receptors to "warp"- WAS ME..My psych put me on CYCLOBENZAPRINE 10mg up to 2x day. I take 1 at bedtime & I am FINALLY ABLE TO SLEEP!!!"

9 / 10
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  • DOODL...
  • August 27, 2010

Flexeril (cyclobenzaprine) "I have Fibromyalgia and compression fractures in my lower back and neck from an automobile accident. I have tried everything for pain and stiffness. I changed doctors and she gave me a prescription for Flexeril 10mg to take at bedtime to help me sleep. For me, this is the best medication I have tried. I had to cut the pills in quarters however because the 10mg was too strong."

9 / 10
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  • finally...
  • Taken for less than 1 month
  • November 20, 2013

"After years of suffering a Rheumatologist finally diagnosed fibromyalgia. He prescribed Flexeril 5 mg. at bedtime. I had forgotten what it feels like to actually be rested in the morning! MUCH less pain the next day as well as not waking up to spasms during the night. The only problem I have with it is constipation, but I started Forteo injections for osteoporosis at the same time which can also be constipating, so I can't blame the Flexeril entirely."

9 / 10
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  • boopt...
  • December 2, 2009

Flexeril (cyclobenzaprine) "I have had fibromyalgia for over 15 years. When my muscles feel extremely "tight"``I definitely hurt more. Thank God for Flexeril! I take 10 mg before bed and this helps me to sleep and feel less muscle pain. I tried to live without this medicine for 1 week and my pain level went up considerably and much more muscle spasms and tightness. I do have a dry mouth especially after I wake up. I do work night shifts as a nurse...this helps me to get better sleep in turn making me feel better after I get up. "

9 / 10
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  • Angel
  • Taken for 10 years or more
  • December 29, 2018

"Using the elimination diagnosis 'protocol' I was determined to have fibromyalgia in 2007. Flexeril, 10mg 3 times per day, has been part of my treatment regardless of the actual pain reliever prescribed since the beginning. My doctor suddenly determines that Flexeril is not safe with my low dosage of pain medication (300 mg Tramadol total per day) and dropped me to 10 mg of Flexeril per day. It is very evident to me that Flexeril contributed significantly to the reduction/elimination of the throbbing nerve pain that the 'opioid' I am taking does not touch. 12 years at 30 mg per day in three 10 mg doses resulted in zero side effects and a better quality of life compared to the current lower dosage."

10 / 10
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  • hubble
  • Taken for 6 months to 1 year
  • October 3, 2018

"After trying a bunch of medications over the course of a couple years, I found the Chronic Pain & Fatigue Research center I've been on gapapentin, pregabalin, hydrocodone, methotrexate, doxepin, high levels of NSAIDs, SNRIs, SSRIs, etc, but nothing has been as effective as Dr recommendation of Flexeril (cyclobenzaprine) 5mg/daily. It has relatively few side effects out of drugs I've tried for fibro. If you're not getting the results you'd like, work with your physician to get off opiates and try this, or one of the others Dr. Clauw references in his talks. It has seriously saved my quality of life."

10 / 10
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  • Brook...
  • February 7, 2012

Flexeril (cyclobenzaprine) "Flexeril worked GREAT for the first few months I was on it. It totally got rid of the pain between each shoulder blade and spine, and helped the rest of my back as well. I was taking 10 mg once a night, but I was prescribed to take it 3 times daily (I like to make my pain meds last as long as I can). This pill was like a miracle to me. But overnight, it completely stopped working. There wasn't no decrease in the effectiveness before it stopped working at all, it just stopped with no warning. Every few days, I would take one to see if it'd work, but no such luck. A few months later, I tried taking one, didn't work, so I took another one like an hour later and still nothing. But I tend to have a high tolerance to all pain meds. Try it out!"

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  • Anonymous
  • November 25, 2009

Flexeril (cyclobenzaprine) "Helps overall but leaves me with a terrible hung-over type grogginess until mid-afternoon the next day. Doctor said it should go away after a week but no luck - still had the next day druggy haze feeling even after 3 weeks on it. I do still use it occasionally for bad shoulder or back spasms but not everyday for my fibromyalgia anymore."

6 / 10
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  • Anonymous
  • November 7, 2009

Flexeril (cyclobenzaprine) "Knocks me out! Which allows me to sleep, at least for a few hours until it wears off. I could not take this during times I need to remain awake, but when I want to be able to fall asleep, it is wonderful!"

8 / 10
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  • Knotl...
  • Taken for less than 1 month
  • April 15, 2016

"Experience chronic neck/upper body muscle tension after 3 cervical surgeries including fusion w/ plates (c567) & Artificial discs (c3&4). Have disc issues w L5- S1, too. Also diagnosed recently w/ fibromyalgia (but probably had it for many hrs prior). This drug relieved the chronic pain of muscle tension (spasms, knots) . Took 10 mg at bedtime initially. Best sleep ever but I could have slept 14 hrs! I woke up very drowsy. Instead take only 5 mg early in evening. No other side effects. I take only as needed as a precaution."

9 / 10
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  • MauiJan
  • Taken for 1 to 6 months
  • March 16, 2016

"Finally, like the other lady said, something for Fibromyalgia that totally works. The longer you take it (3.5 months at this time) the less pain I have had. It has been wonderful not having pain. I do experience sleepiness and need more sleep but with Fibro, you do anyway. Unfortunately, my heart rate has been steadily climbing. "

10 / 10
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28 Report
  • Lizzi...
  • July 23, 2015

"Cyclobenzaprine actually CAUSES me to feel joint pain plus overall fatigue, far beyond what fibromyalgia does. A few days after taking this, I noticed feeling depression out of nowhere, getting short of breath quickly (I'm fairly young & work out 5-6 days a week for 60-70 minutes a day, so this abnormal for me), my chest felt tight, my body was stiff as a board. I dropped this & just one day later I felt completely back to my normal self."

1 / 10
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  • Anonymous
  • September 26, 2010

Flexeril (cyclobenzaprine) "This muscle relaxer is very good at relaxing my muscle if taken for several days; it is slow acting. The negative side is that my doctor only lets me take it when I have a flare-up, so I have to take it about 4 days before I get any relief and then when I stop taking it, it stays in my system for about 3 days and then I go right back to my normal baseline level of pain. I wish I could take it everyday because I feel so much less pain overall when I have it built up in my system."

7 / 10
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  • def
  • January 6, 2015

"My true experience with (Flexeril) is very positive.It will reduce your Flare-ups. I have Chronic Myofascial pain Syndrome and Post-Traumatic Fibromyalgia. I received this Disability from a (Auto Accident). Post means (Trauma). It is wise to make sure you are with the proper Practitioner. Not everyone is capable of treating this painful illness."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 15, 2012

"I have had severe pain and heat in my hips, legs and feet. The rest of my body was also very uncomfortable. The cyclobenzaprine has really brought the continual pain down and the "heat" has also tapered. I can now get some sleep. It still flares when I exercise too hard, but it is much less severe."

9 / 10
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33 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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