Cyclobenzaprine Dosage

Usual Adult Dose for Muscle Spasm

Initial dose: 5 mg orally 3 times a day.
Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day.

Alternate doses include the 15 mg extended release capsule or 30 mg extended release capsule orally once a day.

Usual Geriatric Dose for Muscle Spasm

Initial dose: 5 mg, titrating slowly upward based on individual patient response.

Extended release formulations are not recommended for use in elderly patients.

Usual Pediatric Dose for Muscle Spasm

Pediatric patients 15 years of age and older:
Initial dose: 5 mg orally 3 times a day.
Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Mild hepatic impairment:
Immediate release: Initial dose: 5 mg, titrating slowly upward
Extended release: Not recommended

Moderate to severe hepatic impairment:
Not recommended

Precautions

Safety and effectiveness have not been established in pediatric patients less than 15 years of age.

Dialysis

Data not available

Other Comments

Use of cyclobenzaprine for periods longer than 2 to 3 weeks is not generally recommended.

See also...